Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marine Cacheux"'
Autor:
Kevin N. Su, Yina Ma, Marine Cacheux, Zeki Ilkan, Nour Raad, Grace K. Muller, Xiaohong Wu, Nicole Guerrera, Stephanie L. Thorn, Albert J. Sinusas, Marc Foretz, Benoit Viollet, Joseph G. Akar, Fadi G. Akar, Lawrence H. Young
Publikováno v:
JCI Insight, Vol 7, Iss 8 (2022)
Metabolic stress is an important cause of pathological atrial remodeling and atrial fibrillation. AMPK is a ubiquitous master metabolic regulator, yet its biological function in the atria is poorly understood in both health and disease. We investigat
Externí odkaz:
https://doaj.org/article/89a8b570681a43d5b439e41dbe042fb5
Autor:
Lukas J. Motloch, Marine Cacheux, Kiyotake Ishikawa, Chaoqin Xie, Jun Hu, Jaume Aguero, Kenneth M. Fish, Roger J. Hajjar, Fadi G. Akar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Background SERCA2a gene transfer (GT) improves mechano‐electrical function in animal models of nonischemic heart failure Whether SERCA2a GT reverses pre‐established remodeling at an advanced stage of ischemic heart failure is unclear. We sought t
Externí odkaz:
https://doaj.org/article/35cb35932287459a889787e0ed9d9a8b
Autor:
Michael W. Rudokas, Marine Cacheux, Xiaohong Wu, Madelyn E. Hummel, Lawrence H. Young, Fadi G. Akar
Publikováno v:
Biophysical Journal. 122:380a-381a
Autor:
Lu Zhang, Chen-Leng Cai, Zeki Ilkan, Dongtak Jeong, Philip Bittihn, Fadi G. Akar, Marine Cacheux, Nour Raad, Delaine K. Ceholski, Roger J. Hajjar, Francesca Stillitano, Evangelia G. Kranias, Erik Kohlbrenner
Publikováno v:
Circulation
Background: Arginine (Arg) 14 deletion (R14del) in the calcium regulatory protein phospholamban (hPLN R14del ) has been identified as a disease-causing mutation in patients with an inherited cardiomyopathy. Mechanisms underlying the early arrhythmoge
Publikováno v:
Circulation Research. 131
AMP-activated protein kinase (AMPK), a master metabolic sensor, plays a central role in the regulation of mitochondrial (mito) function. AMPK activation inhibits mito fission potentially by modulating mito dynamics proteins, including dynamin-related
Publikováno v:
Circulation Research. 131
Atrial specific AMPK deletion leads to spontaneous onset of AF. Electrophysiological mechanisms underlying this heightened propensity remain unknown. We hypothesized that AMPK inactivation forms atrial triggered activity leading to atrial ectopy and
Autor:
Marine Cacheux, Fadi G Akar
Publikováno v:
European Heart Journal. 43:2157-2159
Publikováno v:
Cardiovascular Signaling in Health and Disease ISBN: 9783031083082
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989a2731b954d72c2df3a9eb009ffbb4
https://doi.org/10.1007/978-3-031-08309-9_6
https://doi.org/10.1007/978-3-031-08309-9_6
Autor:
Yassine Sassi, Benjamin Strauss, Marine Cacheux, Joseph G. Akar, Emerson Obus, Anthony S. Fargnoli, Lahouaria Hadri, Michael G. Katz, Fadi G. Akar, Malik Bisserier, James P. Hummel
Publikováno v:
Heart Rhythm
Background Electrophysiological (EP) properties have been studied mainly in the monocrotaline model of pulmonary arterial hypertension (PAH). Findings are confounded by major extrapulmonary toxicities, which preclude the ability to draw definitive co
Autor:
Nour Raad, Marine Cacheux, Ludovic Benard, Stefan Feske, Zeki Ilkan, Jean-Sébastien Hulot, Benjamin Strauss, Fadi G. Akar, Jun Hu
Publikováno v:
Circulation. Arrhythmia and Electrophysiology
Supplemental Digital Content is available in the text.
Background: STIM1 (stromal interaction molecule 1) is a calcium (Ca2+) sensor that regulates cardiac hypertrophy by triggering store-operated Ca2+ entry. Because STIM1 binding to phospholamb
Background: STIM1 (stromal interaction molecule 1) is a calcium (Ca2+) sensor that regulates cardiac hypertrophy by triggering store-operated Ca2+ entry. Because STIM1 binding to phospholamb