Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Marina Zvartau-Hind"'
Autor:
Carly Barnett, Alexander Kurz, Gareth Maher-Edwards, Diane Boswell, Michael Gold, Beth Safirstein, Juan Paul Schronen, Carolyn Watson, John A. Ascher, Manuel Fernandez, John T. Davies, Orazio Zanetti, Marina Zvartau-Hind
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Background Two previous studies of SB742457, a 5-hydroxytryptamine (5-HT 6 ) receptor antagonist, suggested the efficacy of improvements in cognition and global outcome in Alzheimer's disease (AD). Methods Two randomized, placebo-controlled trials in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20efebd3530e4592d4f181315eff4299
https://doi.org/10.1016/j.trci.2015.04.001
https://doi.org/10.1016/j.trci.2015.04.001
Autor:
Barbara Jeter, William A. Hallett, Marina Zvartau-Hind, Michael Gold, Paul M. Matthews, Julian C. Matthews, Eric M. Reiman, Graham E. Searle, Dan Bandy, Andy Brown, Mary Castiglia, Ian J. Dixon, Sofia Tzimopoulou, Nick P. Bird, Thomas E. Nichols, Kewei Chen, Vincent J. Cunningham, Brandon Whitcher, Robert Lai, Narinder Lotay, Eugenii A. Rabiner, Prafull Mistry
Publikováno v:
Journal of Alzheimer's Disease. 22:1241-1256
Here we report the first multi-center clinical trial in Alzheimer's disease (AD) using fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) measures of brain glucose metabolism as the primary outcome. We contrasted effects of 12 months trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b62062158825256b0a423f7df4164a1
https://doi.org/10.3233/jad-2010-100939
https://doi.org/10.3233/jad-2010-100939
Autor:
Gary E. Landreth, Suzanne Craft, Ülla Linnamägi, Sally Egginton, Sharon Sawchak, Marina Zvartau-Hind, Claire Alderton, Michael Gold, Ann M. Saunders, Michael C. Irizarry
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 30:131-146
Background/Aims: A phase II study of the peroxisome proliferator-activated receptor-γ agonist rosiglitazone extended release (RSG XR) in mild-to-moderate Alzheimer’s disease (AD) detected a treatment benefit to cognition in apolipoprotein E(APOE)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e364c78d2572c1be6bea8c237d9ba75f
https://doi.org/10.1159/000318845
https://doi.org/10.1159/000318845
Autor:
Marc E. Risner, Jill F.B. Altman, Suzanne Craft, George C. Ormandy, Marina Zvartau-Hind, Allen D. Roses, David A. Hosford, I M Foley, Ann M. Saunders
Publikováno v:
The Pharmacogenomics Journal. 6:246-254
Mild-to-moderate AD patients were randomized to placebo or rosiglitazone (RSG) 2, 4 or 8 mg. Primary end points at Week 24 were mean change from baseline in AD Assessment Scale-Cognitive (ADAS-Cog) and Clinician's Interview-Based Impression of Change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b741eb6d5b8e0c7dcd3c9034db5c3954
https://doi.org/10.1038/sj.tpj.6500369
https://doi.org/10.1038/sj.tpj.6500369
Publikováno v:
Expert Review of Neurotherapeutics. 2:285-294
The 'Decade of the Brain' (1990-2000) saw unprecedented advances in neurosciences including multiple sclerosis. It could have not been more aptly named, as it produced a shift in the paradigm of multiple sclerosis management, making multiple sclerosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb93a6564abd242b9a03794703487a20
https://doi.org/10.1586/14737175.2.3.285
https://doi.org/10.1586/14737175.2.3.285
Autor:
Rana K. Zabad, Christina Caon, Robert P. Lisak, Omar Khan, Marina Zvartau-Hind, Alexandros Tselis
Publikováno v:
CNS Drugs. 16:563-578
The past decade has seen unprecedented advances in the development of disease-modifying therapies for relapsing-remitting multiple sclerosis (RRMS), a disease that has a worldwide prevalence of two million patients. Four agents with the ability to mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ba799cf02af58c56fb75ff3a452c40
https://doi.org/10.2165/00023210-200216080-00005
https://doi.org/10.2165/00023210-200216080-00005
Autor:
Christina Caon, Alexandros Tselis, James Y. Garbern, Deena Lisak, John Kamholz, Moeen U Din, Marina Zvartau-Hind, Robert P. Lisak, Omar Khan, Mickey Cochran
Publikováno v:
Multiple Sclerosis Journal. 7:185-188
Fourteen consecutive clinically definite relapsing-remitting multiple sclerosis (MS) patients were treated with monthly intravenous cyclophosphamide (CTX) for 6 months. All had experienced severe clinical deterioration during the 12 months prior to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5753f3bd6c6583d72139d651c95be08a
https://doi.org/10.1177/135245850100700309
https://doi.org/10.1177/135245850100700309
Publikováno v:
Neurology. 60:323-325
Intercaudate nucleus ratio (ICR) is a linear measure of brain atrophy that does not require software application and is independent of image acquisition techniques. The authors examined the relationship between ICR and disability in 190 patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf122f10dc6fd2a40fbc3af607e2c65
https://doi.org/10.1212/01.wnl.0000042094.91478.4a
https://doi.org/10.1212/01.wnl.0000042094.91478.4a
Autor:
Gwen Adshead, Stephen Attard, Jeremy Berman, Sadgun Bhandari, Rahul Bhattacharya, Kamaldeep Bhui, Peter Byrne, David J. Castle, Heather A. Church, Anthony Cleare, John Cookson, John M. Cooney, Frances Connan, Aiden Corvin, Michael Crawford, Ross A. Dunne, Abebaw Fekadu, Peter Fitzgerald, Stuart Foyle, Michael Gill, Stephen Ginn, Nick Goddard, Claire Henderson, Matthew Hotopf, Assen V. Jablensky, Caroline Jacob, Shaloo Jain, Jelena Jankovic Gavrilovic, Mark Jones, Nicola Kalk, John E. Kraus, William Lee, Anne Lingford-Hughes, James V. Lucey, Paul Mackin, Declan M. McLoughlin, Carine Minne, Joanna Moncrieff, Stirling Moorey, Jean O'Hara, Michael F. O'Neill, Oyedeji Oyebode, Lisa A. Page, Catherine Penny, Michael Phelan, Martin Prince, Lena Rane, Kylie D. Reed, Ajit Shah, Thordur Sigmundsson, Shubuladè Smith, Shankarnanarayan Srinath, Julian Stern, Sue Stuart-Smith, Susannah Whitwell, Séan Whyte, Adam Winstock, Pádraig Wright, Allan Young, Marina Zvartau-Hind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff901283820f5f204529a522feae74a
https://doi.org/10.1016/b978-0-7020-3397-1.00041-0
https://doi.org/10.1016/b978-0-7020-3397-1.00041-0
