Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Marina Zenzola"'
Autor:
Claudia Carlucci, Luisa Pisano, Giuseppe Romanazzi, Renzo Luisi, Giovanna Parisi, Emanuela Capitanelli, Leonardo Degennaro, Marina Zenzola
Publikováno v:
Pure and Applied Chemistry. 88:631-648
Interest in molecular structures bearing four-membered heterocycles (FMHs) is growing due to the possibility to explore new regions of the chemical space and get new lead molecules. Our interest in the development of divergent synthesis of functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3e8773f5e0f51776b27f82c8ca3d81
https://doi.org/10.1515/pac-2016-0602
https://doi.org/10.1515/pac-2016-0602
Publikováno v:
Angewandte Chemie (International Ed. in English)
The transfer of nitrogen atoms is extremely valuable in the preparation of medicinal compounds. Here, a new system for NH transfer is developed to prepare sulfoximines, which are emerging as valuable motifs for drug discovery. This is achieved using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3b3959630c8c462a74a3e85cc6c223
http://europepmc.org/articles/PMC5074267
http://europepmc.org/articles/PMC5074267
Publikováno v:
The Journal of Organic Chemistry. 80:6391-6399
Sulfoximines are of considerable interest for incorporation into medicinal compounds. A convenient synthesis of N-protected sulfoximines is achieved, under mild conditions, by rhodium-catalyzed transfer of carbamates to sulfoxides. The first examples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0340acfd1728cedd83f455b7ece7c218
https://doi.org/10.1021/acs.joc.5b00844
https://doi.org/10.1021/acs.joc.5b00844
Autor:
Renzo Luisi, Carlo Franchini, Solomon Habtemariam, Leonardo Degennaro, Maria Maddalena Cavalluzzi, Giovanni Lentini, Annunziatina Laurino, Marina Zenzola, Rosanna Matucci
Alternative and complementary procedures were adopted for preparing 2-arylazetidine derivatives in moderate to good yields. Preliminary biological evaluation of 2-arylazetidines as ligands of nicotinic acetylcholine receptors allowed to identify chlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41cbe6ac2b8d933b14e75d44c95715a
http://hdl.handle.net/11365/1189877
http://hdl.handle.net/11365/1189877
Autor:
Leonardo Degennaro, Giuseppe Romanazzi, Sahra St John-Campbell, Renzo Luisi, James A. Bull, Stephen John Chawner, Claudia Carlucci, Arianna Tota, Marina Zenzola
Publikováno v:
Chemical communications (Cambridge, England). 53(2)
Direct synthesis of NH-sulfoximines from sulfides has been achieved through O and NH transfer in the same reaction, occurring with complete selectivity. The reaction is mediated by bisacetoxyiodobenzene under simple conditions and employs inexpensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6bfa768d9e6a29a44cf5573a21743b
https://pubmed.ncbi.nlm.nih.gov/27929152
https://pubmed.ncbi.nlm.nih.gov/27929152
Publikováno v:
ChemInform. 47
An extremely useful method for the conversion of variously substituted sulfoxides to sulfoximines using ammonium carbamate as nitrogen source is reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f28b70b348c390133887087dba86494
https://doi.org/10.1002/chin.201642094
https://doi.org/10.1002/chin.201642094
Autor:
Giovanna Parisi, Marina Zenzola, Laura Carroccia, Luisa Pisano, Leonardo Degennaro, Flavio Fanelli, Giuseppe Romanazzi, Renzo Luisi
Publikováno v:
ChemInform. 47
Starting from readily available C2-substituted thietane 1-oxides, a straightforward synthesis of new C2,C4-disubstituted thietane 1-oxides has been developed by using a lithiation/electrophilic trapping sequence. The chemical and configurational stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2ac8331f8147ebf74b126a0497e5c1
https://doi.org/10.1002/chin.201618105
https://doi.org/10.1002/chin.201618105
Autor:
Giovanna Parisi, Laura Carroccia, Renzo Luisi, Leonardo Degennaro, Giuseppe Romanazzi, Flavio Fanelli, Marina Zenzola, Luisa Pisano
Publikováno v:
The Journal of organic chemistry. 80(24)
Starting from readily available C2-substituted thietane 1-oxides, a straightforward synthesis of new C2,C4-disubstituted thietane 1-oxides has been developed by using a lithiation/electrophilic trapping sequence. The chemical and configurational stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b37c00fae297fee0cf88da0ea2e7138
https://pubmed.ncbi.nlm.nih.gov/26566011
https://pubmed.ncbi.nlm.nih.gov/26566011
Publikováno v:
ChemInform. 46
Sulfoximines are of considerable interest for incorporation into medicinal compounds. A convenient synthesis of N-protected sulfoximines is achieved, under mild conditions, by rhodium-catalyzed transfer of carbamates to sulfoxides. The first examples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cc6bfba86f790ea701efbf00b834b3
https://doi.org/10.1002/chin.201545102
https://doi.org/10.1002/chin.201545102
Autor:
Giuseppe Romanazzi, Piero Mastrorilli, Piera Trinchera, Leonardo Degennaro, Luisa Pisano, Marina Zenzola, Rosanna Rizzi, Renzo Luisi, Arianna Giovine, Laura Carroccia
Publikováno v:
ChemInform. 46
This work demonstrates how the directing ability of the azetidine ring could be useful for regioselective ortho-CH functionalization of aryl compounds. Robust polar organometallic (lithiated) intermediates are involved in this synthetic strategy. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7770905c72eb921784181cf148901c1b
https://doi.org/10.1002/chin.201511075
https://doi.org/10.1002/chin.201511075