Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marina W Shirkey"'
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina W. Shirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The beneficial effects attributed to Bifidobacterium are largely attributed to their immunomodulatory capabilities, which are likely to be species- and even strain-specific. However, their strain-specificity in direct and indirect immune mod
Externí odkaz:
https://doaj.org/article/f9fced7d73f84dbda470cc9023254a83
Autor:
Lushen Li, Long Wu, Allison Kensiski, Jing Zhao, Marina W. Shirkey, Yang Song, Wenji Piao, Tianshu Zhang, Zhongcheng Mei, Samuel J. Gavzy, Bing Ma, Vikas Saxena, Young S. Lee, Yanbao Xiong, Xiaofei Li, Xiaoxuan Fan, Reza Abdi, Jonathan S. Bromberg
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Fibroblastic reticular cells (FRCs) play important roles in tolerance by producing laminin α4 (Lama4) and altering lymph node (LN) structure and function. The present study revealed the specific roles of extracellular matrix Lama4 in regulating LN c
Externí odkaz:
https://doaj.org/article/7dc3ca9c1b604d50926310b2f242e3f7
Autor:
Wenji Piao, Lushen Li, Vikas Saxena, Jegan Iyyathurai, Ram Lakhan, Yigang Zhang, Isadora Tadeval Lape, Christina Paluskievicz, Keli L. Hippen, Young Lee, Emma Silverman, Marina W. Shirkey, Leonardo V. Riella, Bruce R. Blazar, Jonathan S. Bromberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The Programmed death-1 (PD-1) and its ligand PD-L1 are critical checkpoints in the regulation of immune responses. Here the authors implicate PD-L1 signalling at lymphatic endothelium in the regulation of transendothelial migration of T cells.
Externí odkaz:
https://doaj.org/article/95f1ec3c1b3240e0a0c30c1a91d6a299
Autor:
Lushen Li, Marina W. Shirkey, Tianshu Zhang, Wenji Piao, Xiaofei Li, Jing Zhao, Zhongcheng Mei, Yizhan Guo, Vikas Saxena, Allison Kensiski, Samuel J. Gavzy, Yang Song, Bing Ma, Jing Wu, Yanbao Xiong, Long Wu, Xiaoxuan Fan, Holly Roussey, Meng Li, Alexæander S. Krupnick, Reza Abdi, Jonathan S. Bromberg
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Lymph node (LN) fibroblastic reticular cells (FRCs) define LN niches and regulate lymphocyte homeostasis through producing diverse extracellular matrix (ECM) components. We examined the role of ECM laminin α4 (Lama4) using FRC-Lama4 conditional KO P
Externí odkaz:
https://doaj.org/article/5d83d9a7e25f41368b6d68caa9682d5e
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina W. Shirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/00c7b31813ef492b96cdb8838282af9f
Autor:
Samuel J Gavzy, Allison Kensiski, Vikas Saxena, Ram Lakhan, Lauren Hittle, Jegan Iyyathurai, Long Wu, Hima Dhakal, Zachariah L Lee, Lushen Li, Young Lee, Tianshu Zhang, Hnin W Lwin, Marina W Shirkey, Christina M Paluskievicz, Wenji Piao, Emmanuel F Mongodin, Bing Ma, Jonathan S Bromberg
Despite ongoing improvements in regimens to prevent allograft rejection, most cardiac and other types of allografts eventually succumb to chronic vasculopathy, interstitial fibrosis, or endothelial changes, and eventually graft failure. Adaptive immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3c47e6a79dfa7e80976ea8c5894a45
https://doi.org/10.1101/2022.10.13.511915
https://doi.org/10.1101/2022.10.13.511915
Autor:
Bing Ma, Samuel J. Gavzy, Vikas Saxena, Yang Song, Wenji Piao, Hnin Wai Lwin, Ram Lakhan, Jegan Iyyathurai, Lushen Li, Michael France, Christina Paluskievicz, Marina W. Shirkey, Lauren Hittle, Arshi Munawwar, Emmanuel F. Mongodin, Jonathan S. Bromberg
The beneficial effects attributed to Bifidobacterium are largely attributed to their immunomodulatory capabilities, which are likely to be species- and even strain-specific. However, their strain-specificity in direct and indirect immune modulation r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd25d66a9b0cb7c3b894ea2d93063b1
https://doi.org/10.21203/rs.3.rs-1805970/v1
https://doi.org/10.21203/rs.3.rs-1805970/v1
Autor:
Kyle D. Smith, Young Ho Lee, Wenji Piao, Qinshan Li, Keli L. Hippen, Yanbao Xiong, Vikas Saxena, Benjamin M. Cerel, Marina W. Shirkey, Nicholas Toney, Christina Paluskievicz, Reza Abdi, Bruce R. Blazar, Jonathan S. Bromberg, Tianshu Zhang, Thomas Simon, Lushen Li
Publikováno v:
J Clin Invest
Lymph node stromal cells (LNSCs) regulate immunity through constructing lymphocyte niches. LNSC-produced laminin α5 (Lama5) regulates CD4(+) T cells but the underlying mechanisms of its functions are poorly understood. Here we show that depleting La
Autor:
Wenji Piao, Lushen Li, Vikas Saxena, Jegan Iyyathurai, Ram Lakhan, Yigang Zhang, Isadora Tadeval Lape, Christina Paluskievicz, Keli L. Hippen, Young Lee, Emma Silverman, Marina W. Shirkey, Leonardo V. Riella, Bruce R. Blazar, Jonathan S. Bromberg
Publikováno v:
Nature communications. 13(1)
Programmed death-1 (PD-1) and its ligand PD-L1 are checkpoint molecules which regulate immune responses. Little is known about their functions in T cell migration and there are contradictory data about their roles in regulatory T cell (Treg) function
Autor:
Yanbao Xiong, Vikas Saxena, Wenji Piao, Jonathan S. Bromberg, Tianshu Zhang, Christina Paluskievicz, Lushen Li, Jing Zhao, Marina W. Shirkey, Reza Abdi
Publikováno v:
Transplantation. 104:S71-S71