Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marina V. Fridman"'
Autor:
Eleonora A. Braga, Marina V. Fridman, Alexey M. Burdennyy, Vitaly I. Loginov, Alexey A. Dmitriev, Irina V. Pronina, Sergey G. Morozov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13617 (2023)
Long non-coding RNAs (lncRNAs) are crucial players in the pathogenesis of non-small-cell lung cancer (NSCLC). A competing binding of lncRNAs and mRNAs with microRNAs (miRNAs) is one of the most common mechanisms of gene regulation by lncRNAs in NSCLC
Externí odkaz:
https://doaj.org/article/d0d4a97b00bb41ef80fd49843eaa332f
Autor:
Sergey Abramov, Alexandr Boytsov, Daria Bykova, Dmitry D. Penzar, Ivan Yevshin, Semyon K. Kolmykov, Marina V. Fridman, Alexander V. Favorov, Ilya E. Vorontsov, Eugene Baulin, Fedor Kolpakov, Vsevolod J. Makeev, Ivan V. Kulakovskiy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Single-nucleotide variants in enhancers or promoters may affect gene transcription by altering transcription factor binding sites. Here the authors present a meta-analysis empowered by a new statistical method covering thousands of ChIP-Seq experimen
Externí odkaz:
https://doaj.org/article/fb8abbc7f0654d9bb7b8ee5f2d4d9a03
Autor:
Eleonora A. Braga, Marina V. Fridman, Alexey M. Burdennyy, Elena A. Filippova, Vitaly I. Loginov, Irina V. Pronina, Alexey A. Dmitriev, Nikolay E. Kushlinskii
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13620 (2022)
A decrease in the miR-124 expression was observed in various epithelial cancers. Like a classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. Epigenetic mechanisms play a significant role in the regulation of miR-1
Externí odkaz:
https://doaj.org/article/489f445ea2184974824f0c4667552b3d
Autor:
Irina V. Pronina, Leonid A. Uroshlev, Alexey A. Moskovtsev, Danila M. Zaichenko, Elena A. Filippova, Marina V. Fridman, Alexey M. Burdennyy, Vitaly I. Loginov, Tatiana P. Kazubskaya, Nikolay E. Kushlinskii, Alexey A. Dmitriev, Eleonora A. Braga, Olga I. Brovkina
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 824 (2022)
Ovarian cancer (OC) is one of the most common types of cancer among malignancies of the female reproductive system. This pathology is asymptomatic until advanced stages and has a poor prognosis. Our study aimed to search for lncRNA–miRNA–mRNA com
Externí odkaz:
https://doaj.org/article/e2feb5d664f646bc98c2ddd736ffa30f
Autor:
Vitaly I. Loginov, Irina V. Pronina, Elena A. Filippova, Alexey M. Burdennyy, Svetlana S. Lukina, Tatiana P. Kazubskaya, Leonid A. Uroshlev, Marina V. Fridman, Olga I. Brovkina, Natalya V. Apanovich, Alexander V. Karpukhin, Ivan S. Stilidi, Nikolay E. Kushlinskii, Alexey A. Dmitriev, Eleonora A. Braga
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1300 (2022)
Our work aimed to differentiate 20 aberrantly methylated miRNA genes that participate at different stages of development and metastasis of ovarian carcinoma (OvCa) using methylation-specific qPCR in a representative set of clinical samples: 102 prima
Externí odkaz:
https://doaj.org/article/eb0dfe6fd4544a549de064b8c70fc2a0
Autor:
Eleonora A. Braga, Marina V. Fridman, Elena A. Filippova, Vitaly I. Loginov, Irina V. Pronina, Alexey M. Burdennyy, Alexander V. Karpukhin, Alexey A. Dmitriev, Sergey G. Morozov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11193 (2021)
The fundamental novelty in the pathogenesis of renal cell carcinoma (RCC) was discovered as a result of the recent identification of the role of long non-coding RNAs (lncRNAs). Here, we discuss several mechanisms for the dysregulation of the expressi
Externí odkaz:
https://doaj.org/article/68eed44f53564d2f8941fb8c8b2e4be9
Autor:
Elena A. Filippova, Marina V. Fridman, Alexey M. Burdennyy, Vitaly I. Loginov, Irina V. Pronina, Svetlana S. Lukina, Alexey A. Dmitriev, Eleonora A. Braga
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6810 (2021)
Long noncoding RNAs (lncRNAs) have been identified as contributors to the development and progression of cancer through various functions and mechanisms. LncRNA GAS5 is downregulated in multiple cancers and acts as a tumor suppressor in breast cancer
Externí odkaz:
https://doaj.org/article/de2e3dd56cff488fa51c5e6097ccef17
Autor:
Eleonora A. Braga, Marina V. Fridman, Vitaly I. Loginov, Alexey A. Dmitriev, Sergey G. Morozov
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has resulted in the search for new biomarkers. Epigenetic regulatory mechani
Externí odkaz:
https://doaj.org/article/bd227e8c5e054107980efb8b95f41850
Autor:
Eleonora A. Braga, Marina V. Fridman, Alexey A. Moscovtsev, Elena A. Filippova, Alexey A. Dmitriev, Nikolay E. Kushlinskii
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8855 (2020)
Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of regulatory long non-coding RNAs (lncRNAs) competing with protein-coding m
Externí odkaz:
https://doaj.org/article/ae4cf001771a4c59a6f13006561ed2ac
Autor:
Marina A Afanasyeva, Lidia V Putlyaeva, Denis E Demin, Ivan V Kulakovskiy, Ilya E Vorontsov, Marina V Fridman, Vsevolod J Makeev, Dmitry V Kuprash, Anton M Schwartz
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172681 (2017)
We studied functional effect of rs12722489 single nucleotide polymorphism located in the first intron of human IL2RA gene on transcriptional regulation. This polymorphism is associated with multiple autoimmune conditions (rheumatoid arthritis, multip
Externí odkaz:
https://doaj.org/article/1b53b0d793e748d19e0ebb55e673d7eb