Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Marina V. Fridman"'
1
Akademický článek
Landscape of allele-specific transcription factor binding in the human genome
Autor: Sergey Abramov, Alexandr Boytsov, Daria Bykova, Dmitry D. Penzar, Ivan Yevshin, Semyon K. Kolmykov, Marina V. Fridman, Alexander V. Favorov, Ilya E. Vorontsov, Eugene Baulin, Fedor Kolpakov, Vsevolod J. Makeev, Ivan V. Kulakovskiy
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Single-nucleotide variants in enhancers or promoters may affect gene transcription by altering transcription factor binding sites. Here the authors present a meta-analysis empowered by a new statistical method covering thousands of ChIP-Seq experimen
Externí odkaz: https://doaj.org/article/fb8abbc7f0654d9bb7b8ee5f2d4d9a03
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2
Akademický článek
Dysregulation of lncRNA–miRNA–mRNA Interactome as a Marker of Metastatic Process in Ovarian Cancer
Autor: Irina V. Pronina, Leonid A. Uroshlev, Alexey A. Moskovtsev, Danila M. Zaichenko, Elena A. Filippova, Marina V. Fridman, Alexey M. Burdennyy, Vitaly I. Loginov, Tatiana P. Kazubskaya, Nikolay E. Kushlinskii, Alexey A. Dmitriev, Eleonora A. Braga, Olga I. Brovkina
Publikováno v: Biomedicines, Vol 10, Iss 4, p 824 (2022)
Ovarian cancer (OC) is one of the most common types of cancer among malignancies of the female reproductive system. This pathology is asymptomatic until advanced stages and has a poor prognosis. Our study aimed to search for lncRNA–miRNA–mRNA com
Externí odkaz: https://doaj.org/article/e2feb5d664f646bc98c2ddd736ffa30f
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3
Akademický článek
Molecular Mechanisms in Clear Cell Renal Cell Carcinoma: Role of miRNAs and Hypermethylated miRNA Genes in Crucial Oncogenic Pathways and Processes
Autor: Eleonora A. Braga, Marina V. Fridman, Vitaly I. Loginov, Alexey A. Dmitriev, Sergey G. Morozov
Publikováno v: Frontiers in Genetics, Vol 10 (2019)
Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has resulted in the search for new biomarkers. Epigenetic regulatory mechani
Externí odkaz: https://doaj.org/article/bd227e8c5e054107980efb8b95f41850
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4
Regulation of the Key Epithelial Cancer Suppressor miR-124 Function by Competing Endogenous RNAs
Autor: Eleonora A. Braga, Marina V. Fridman, Alexey M. Burdennyy, Elena A. Filippova, Vitaly I. Loginov, Irina V. Pronina, Alexey A. Dmitriev, Nikolay E. Kushlinskii
Publikováno v: International journal of molecular sciences. 23(21)
A decrease in the miR-124 expression was observed in various epithelial cancers. Like a classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. Epigenetic mechanisms play a significant role in the regulation of miR-1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91c1677f71532a6fdafa8a0fa54810d
https://pubmed.ncbi.nlm.nih.gov/36362406
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5
Akademický článek
The single nucleotide variant rs12722489 determines differential estrogen receptor binding and enhancer properties of an IL2RA intronic region.
Autor: Marina A Afanasyeva, Lidia V Putlyaeva, Denis E Demin, Ivan V Kulakovskiy, Ilya E Vorontsov, Marina V Fridman, Vsevolod J Makeev, Dmitry V Kuprash, Anton M Schwartz
Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0172681 (2017)
We studied functional effect of rs12722489 single nucleotide polymorphism located in the first intron of human IL2RA gene on transcriptional regulation. This polymorphism is associated with multiple autoimmune conditions (rheumatoid arthritis, multip
Externí odkaz: https://doaj.org/article/1b53b0d793e748d19e0ebb55e673d7eb
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6
Akademický článek
Ten Hypermethylated lncRNA Genes Are Specifically Involved in the Initiation, Progression, and Lymphatic and Peritoneal Metastasis of Epithelial Ovarian Cancer.
Autor: Braga, Eleonora A.1 (AUTHOR) eleonora10_45@mail.ru, Burdennyy, Alexey M.1 (AUTHOR) danilamihailovich@mail.ru, Uroshlev, Leonid A.2 (AUTHOR) leoniduroshlev@gmail.com, Zaichenko, Danila M.1 (AUTHOR) p.lenyxa@yandex.ru, Filippova, Elena A.1 (AUTHOR) sveta_sergeevna349@mail.ru, Lukina, Svetlana S.1 (AUTHOR) zolly_sten@mail.ru, Pronina, Irina V.1 (AUTHOR) astafevayr@gmail.com, Astafeva, Iana R.1 (AUTHOR) loginov7w@gmail.com, Fridman, Marina V.2 (AUTHOR) marina-free@mail.ru, Kazubskaya, Tatiana P.3 (AUTHOR) oncogen5@ronc.ru, Loginov, Vitaly I.1 (AUTHOR) alexey.moscovtsev@gmail.com, Dmitriev, Alexey A.4 (AUTHOR) alex_245@mail.ru, Moskovtsev, Aleksey A.1,3,5 (AUTHOR) kne3108@gmail.com, Kushlinskii, Nikolay E.3 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11843. 32p.
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7
Akademický článek
Various LncRNA Mechanisms in Gene Regulation Involving miRNAs or RNA-Binding Proteins in Non-Small-Cell Lung Cancer: Main Signaling Pathways and Networks.
Autor: Braga, Eleonora A.1,2 (AUTHOR) burdennyy@gmail.com, Fridman, Marina V.3 (AUTHOR) marina-free@mail.ru, Burdennyy, Alexey M.1 (AUTHOR) loginov7w@gmail.com, Loginov, Vitaly I.1,2 (AUTHOR) zolly_sten@mail.ru, Dmitriev, Alexey A.4 (AUTHOR) alex_245@mail.ru, Pronina, Irina V.1 (AUTHOR) sergey_moroz@list.ru, Morozov, Sergey G.1 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 17, p13617. 34p.
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8
Akademický článek
Regulation of the Key Epithelial Cancer Suppressor miR-124 Function by Competing Endogenous RNAs.
Autor: Braga, Eleonora A.1,2 (AUTHOR) eleonora10_45@mail.ru, Fridman, Marina V.3 (AUTHOR), Burdennyy, Alexey M.1 (AUTHOR), Filippova, Elena A.1 (AUTHOR), Loginov, Vitaly I.1,2 (AUTHOR), Pronina, Irina V.1 (AUTHOR), Dmitriev, Alexey A.4 (AUTHOR), Kushlinskii, Nikolay E.5 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 21, p13620. 25p.
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