Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Marina V. Aksenova"'
Autor:
Marina V. Aksenova
Publikováno v:
Актуальные проблемы филологии и педагогической лингвистики, Iss 3, Pp 170-176 (2018)
The subject of the article is the genre of travelogue that has not yet a final definition in modern literature study. History of the genre, as well as such literary phenomenon as literary travel are examined. Development of the genre is briefly chara
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37540 (2012)
HIV-1 viral protein Tat partially mediates the neural dysfunction and neuronal cell death associated with HIV-1 induced neurodegeneration and neurocognitive disorders. Soy isoflavones provide protection against various neurotoxic insults to maintain
Externí odkaz:
https://doaj.org/article/c0118806d6164099bd7e3b3233cbb9f1
Autor:
Michael Shtutman, Hao Ji, Edsel A. Peña, Vitali Sikirzhytski, Eugenia V. Broude, Michael D. Wyatt, Biyun Cui, Justin Sybrand, Jun Zhu, Diana Odhiambo, Jill R. Turner, Ilya Safro, Sofia Lizzaraga, Marina V. Aksenova, Mathew Lucius
HIV-1 Associated Neurocognitive Disorder (HAND) is commonly seen in HIV-infected patients. Viral proteins including Tat cause neuronal toxicity and is worsened by drugs of abuse. To uncover potential targets for anti-HAND therapy, we employed a liter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2740faa05d1b70315e9d10b96f41ee36
Autor:
Eugenia V. Broude, Gabrielle H. Levon, Vitali Sikirzhytski, Matthew D Lucius, B. Celia Cui, Michael Shtutman, Sofia B. Lizarraga, Marina V. Aksenova, Zachary T. Mack, Michael D. Wyatt, Diana Odhiambo, Charlotte Pollack
Publikováno v:
Biochem Pharmacol
Stress granules (SGs) are non-membranous cytosolic protein-RNA aggregates that process mRNAs through stalled translation initiation in response to cellular stressors and in disease. DEAD-Box RNA helicase 3 (DDX3) is an active target of drug developme
Publikováno v:
Experimental Neurology. 248:228-235
HIV-1 enters the central nervous system early in infection; although HIV-1 does not directly infect neurons, HIV-1 may cause a variety of neurological disorders. Neuronal loss has been found in HIV-1, but synaptodendritic injury is more closely assoc
Filamentous actin protein (F-actin) plays a major role in spinogenesis, synaptic plasticity, and synaptic stability. Changes in dendritic F-actin rich structures suggest alterations in synaptic integrity and connectivity. Here we provide a detailed p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0308fa01b037ad542ea6b710eeadaba9
https://europepmc.org/articles/PMC4781749/
https://europepmc.org/articles/PMC4781749/
Publikováno v:
Journal of Neuroimmune Pharmacology. 7:599-608
The interactive effects of HIV-1 infection and methamphetamine (METH) abuse in producing cognitive dysfunction represent a serious medical problem; however, the neural mechanisms underlying this interactive neurotoxicity remain elusive. In this study
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Frontiers in Microbiology
Frontiers in Microbiology
Illicit drugs, such as cocaine, are known to increase the likelihood and severity of HIV-1 associated neurocognitive disorders (HAND). In the current studies synaptic integrity was assessed following exposure to low concentrations of the HIV-1 viral
Publikováno v:
Neuroscience Letters. 475:174-178
Since the beginning of the highly active antiretroviral therapy (HAART) era, epidemiological evidence indicates an increasing incidence of Alzheimer's (AD)-like brain pathology in aging HIV patients. Emerging evidence warns of potential convergent me
Publikováno v:
Experimental Neurology. 219:586-590
This study reports that the cysteine 22 → glycine 22 substitution in the HIV-1 Tat 1–86 B significantly attenuates its neurotoxicity. Consistent with previous studies, direct interactions of rat hippocampal cells with Tat 1–86 B were shown to c