Anti-inflammatory effect of interleukin-6 highly enriched in secretome of two clinically relevant sources of mesenchymal stromal cells

Autor: Marianne Dedier, Brice Magne, Muriel Nivet, Sébastien Banzet, Marina Trouillas

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Despite several advances in the field of regenerative medicine, clinical management of extensive skin wounds or burns remains a major therapeutic issue. During the past few years, Mesenchymal Stromal Cells (MSCs) have emerged as a novel therapeutic t

Externí odkaz: https://doaj.org/article/a5606f201a72404ca4be5803678d02d6

Development of extracellular vesicle-based medicinal products: A position paper of the group 'Extracellular Vesicle translatiOn to clinicaL perspectiVEs – EVOLVE France'

Autor: Emilie Velot, Marina Trouillas, Joël Chopineau, J. Peltzer, Sophie Brouard, Olivier Favre-Bulle, Jérôme Larghero, Tristan Montier, Amanda K. A. Silva, Florence Gazeau, Phlippe Mauduit, Jean-Hugues Trouvin, Arnaud Bianchi, Noëlle Mathieu, Christian Jorgensen, Matti Ullah, Kelly Aubertin, Philippe Menasché, Surendar Arumugam, Jolanda Spadavecchia, C. Aussel, Danièle Noël, Wilfrid Boireau, M. Dedier, Sébastien Jauliac, Sébastien Banzet, Jean-Marie Bach, Antoine Monsel, Max Piffoux, Kondareddy Cherukula, Marie Morille, Célia Ravel, Christophe Martinaud, Chantal M. Boulanger, Claire Wilhelm, Mathilde Mosser, Olivier Blanc-Brude, Nicolas Sailliet, Pierre-Emmanuel Rautou, Nathalie Luciani, Isabelle Raymond-Letron, Céline Elie-Caille, Gabriel Rahmi, Anna C. Sebbagh

Publikováno v: Advanced Drug Delivery Reviews
Advanced Drug Delivery Reviews, Elsevier, 2021, 179, pp.114001. ⟨10.1016/j.addr.2021.114001⟩
Advanced Drug Delivery Reviews, 2021, 179, pp.114001. ⟨10.1016/j.addr.2021.114001⟩

International audience; Extracellular vesicles (EV) are emergent therapeutic effectors that have reached clinical trial investigation. To translate EV-based therapeutic to clinic, the challenge is to demonstrate quality, safety, and efficacy, as requ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607492892c07dcbf68c27bb32eea9b55
https://hal.archives-ouvertes.fr/hal-03412034

A comparative analysis of IL-1β-primed MSC derived from two sources with a focus on wound healing potential

Autor: Sébastien Banzet, M. Dedier, Muriel Nivet, J. Peltzer, Brice Magne, Marina Trouillas

Publikováno v: Cytotherapy. 23:S49-S50

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3094d1342cdef073993140b7d5bd88e0
https://doi.org/10.1016/s1465324921003297

Interest of interleukin-1β priming on various sources of MSC for wound healing: role of interleukin-6, a MSC secreted factor

Autor: Muriel Nivet, J. Peltzer, Sébastien Banzet, Marina Trouillas, Brice Magne, M. Dedier

Publikováno v: Cytotherapy. 22:S109-S110

Background & Aim Deep and extensive skin wounds and burns are treated with autologous Split-Thickness Skin Grafts, with a possible combination of adjuvant therapy, or grafted with Cultured Epidermal Autografts (CEAs) when donor sites are limited. Des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a8481f7c552105b24fda3ed880f5294
https://doi.org/10.1016/j.jcyt.2020.03.197

IL-1β–Primed Mesenchymal Stromal Cells Improve Epidermal Substitute Engraftment and Wound Healing via Matrix Metalloproteinases and Transforming Growth Factor-β1

Autor: Muriel Nivet, Bernard Coulomb, M. Dedier, Jean-Jacques Lataillade, Marina Trouillas, Brice Magne, Sébastien Banzet

Publikováno v: Journal of Investigative Dermatology. 140:688-698.e21

Since the 1980s, deep and extensive skin wounds and burns are treated with autologous split-thickness skin grafts, or cultured epidermal autografts, when donor sites are limited. However, the clinical use of cultured epidermal autografts often remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc1aad8d5b5a71df293f9e94961c2f0
https://doi.org/10.1016/j.jid.2019.07.721