Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Marina Trombetta Lima"'
Autor:
Angelica Sabogal, Alejandro Marmolejo, Marina Trombetta Lima, Asmaa Oun, Tingting Chen, Jari Koistinaho, Šarka Lehtonen, Arjan Kortholt, Barbara Bakker, Bart Eggen, Erik Boddeke, Amalia Dolga
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S254-S255 (2023)
Externí odkaz:
https://doaj.org/article/857f9ccf5da049a092ed81bdbafca19b
Autor:
Mohammad Khoonkari, Dong Liang, Marina Trombetta Lima, Tjitze van der Land, Yuanke Liang, Jianwu Sun, Amalia Dolga, Marleen Kamperman, Patrick van Rijn, Frank A. E. Kruyt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6520 (2022)
Glioblastoma multiforme (GBM) is the most aggressive brain tumor in adults. In addition to genetic causes, the tumor microenvironment (TME), including stiffening of the extracellular matrix (ECM), is a main driver of GBM progression. Mechano-transduc
Externí odkaz:
https://doaj.org/article/d4c230a0f0bc494ea2d21b7041a9b3ac
Autor:
Marina Trombetta Lima
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Glioblastoma multiforme (G BM), ou astrocitoma grau IV, é o tumor mais comum e letal do sistema nervoso central. Uma de suas características mais marcantes é seu alto potencial invasivo do tecido normal adjacente. Neste processo, o remodelamento d
Autor:
Isabele F. Moretti, Antonio M. Lerario, Marina Trombetta-Lima, Paula R. Sola, Roseli da Silva Soares, Sueli M. Oba-Shinjo, Suely K. N. Marie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Glioblastoma (GBM) is the most aggressive brain primary malignancy. Toll-like receptor 4 (TLR4) has a dual role in cell fate, promoting cell survival or death depending on the context. Here, we analyzed TLR4 expression in different grades of
Externí odkaz:
https://doaj.org/article/dbd539efc27248eda907583955f9ce84
Autor:
Juliane, Rizzi, Tatiana Rojo, Moro, Sheila Maria Brochado, Winnischofer, Guilherme Augusto, Colusse, Camila Silva, Tamiello, Marina, Trombetta-Lima, Guilhermina Rodrigues, Noleto, Amalia M, Dolga, Maria Eugênia Rabello, Duarte, Miguel Daniel, Noseda
Publikováno v:
International Journal of Biological Macromolecules. 224:584-593
Several polysaccharides are considered to be "biological response modifiers" (BRM) - these refer to biomolecules that augment immune responses and can be derived from a variety of sources. Microalgae produce a diverse range of polysaccharides and cou
Autor:
Nshunge Musheshe, Asmaa Oun, Angélica María Sabogal-Guáqueta, Marina Trombetta-Lima, Sarah C. Mitchel, Ahmed Adzemovic, Oliver Speek, Francesca Morra, Christina H. J. T. van der Veen, Frank Lezoualc’h, Xiaodong Cheng, Martina Schmidt, Amalia M. Dolga
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 314 (2022)
Exchange proteins directly activated by cAMP (Epac) proteins are implicated in a wide range of cellular functions including oxidative stress and cell survival. Mitochondrial-dependent oxidative stress has been associated with progressive neuronal dea
Externí odkaz:
https://doaj.org/article/009fc53d16c244329256a53ee1ef32d8
Autor:
Gabriel Levin, Tatiane Maldonado Coelho, Nathali Guimarães Nóbrega, Marina Trombetta-Lima, Mari Cleide Sogayar, Ana Claudia Oliveira Carreira
Publikováno v:
Reproductive Biology and Endocrinology, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Matrix metalloproteinases (Mmps) and their tissue inhibitors (Timps) are widely recognized as crucial factors for extracellular matrix remodeling in the ovary and are involved in follicular growth, ovulation, luteinization, and lu
Externí odkaz:
https://doaj.org/article/5742b11628b4451d8c012f6ca4ef15da
Autor:
Greeshma Jain, Marina Trombetta-Lima, Irina Matlahov, Hennrique Taborda Ribas, Amalia M. Dolga, Patrick C.A. van der Wel
Huntington’s disease (HD) is a neurodegenerative disorder caused by the expansion of the polyglutamine (polyQ) segment in the exon 1 of the huntingtin (HttEx1) protein. This polyQ expansion leads to protein misfolding and the formation of β-sheet-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aacfd040c383509b36aec419001a05e1
https://doi.org/10.1101/2023.04.24.537565
https://doi.org/10.1101/2023.04.24.537565
Autor:
Angelica Maria Sabogal-Guaqueta, Alejandro Marmolejo-Garza, Marina Trombetta Lima, Asmaa Oun, Jasmijn Hunneman, Tingting Chen, Jari Koistinaho, Sarka Lehtonen, Arjan Kortholt, Barbara M. Bakker, Bart J.L. Eggen, Erik Boddeke, Amalia Dolga
Metabolic reprogramming is a hallmark of the immune cells in response to inflammatory stimuli. This metabolic process involves a switch from oxidative phosphorylation (OXPHOS) to glycolysis, or alterations in other metabolic pathways. However, most o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ad3968ecb5ae6759bcf92cbb4b113cf
https://doi.org/10.1101/2023.03.10.531955
https://doi.org/10.1101/2023.03.10.531955
Autor:
Asmaa Oun, Emmy Hoeksema, Ahmed Soliman, Famke Brouwer, Fabiola García-Reyes, Henderikus Pots, Marina Trombetta-Lima, Arjan Kortholt, Amalia M. Dolga
Publikováno v:
International Journal of Molecular Sciences, 24(2):1644. MDPI AG
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1644
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1644
Dysfunction of the immune system and mitochondrial metabolism has been associated with Parkinson’s disease (PD) pathology. Mutations and increased kinase activity of leucine-rich repeat kinase 2 (LRRK2) are linked to both idiopathic and familial PD