Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Marina Tinel"'
Autor:
Dominique Pessayre, Alain Berson, Claude Wolf, Alain Grodet, Sophie C. Cazanave, Gérard Feldmann, Marina Tinel, Veronique Descatoire
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 318:444-454
Like other nonsteroidal anti-inflammatory drugs, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide) triggers hepatitis in a few recipients. Although nimesulide has been shown to uncouple mitochondrial respiration and cause hepatocyte necrosis in the
Autor:
Nathalie Vadrot, Gérard Feldmann, Véronique Descatoire, Alain Grodet, Jean Paul Thénot, Marina Tinel, Alain Berson, Dominique Pessayre
Publikováno v:
Hepatology. 39:655-666
The hepatotoxicity of several drugs is increased by mild viral infections. During such infections, death receptor ligands are expressed at low levels, and most parenchymal cells survive. We tested the hypothesis that subliminal death receptor stimula
Autor:
Marie-Pierre Junier, Patrick A. Dreyfus, Camila V. Esguerra, Muriel Coulpier, Marina Tinel, Mathias Bähr, Pascal Legendre
Publikováno v:
1998, 12 (3), pp.168-177. ⟨10.1006/mcne.1998.0708⟩
Motoneuronal degenerative diseases are characterized by their progressivity; once affected, the motoneurons remain in altered states during an intermediate phase of degeneration prior to their final disappearance. Whether this survival period coincid
Autor:
Marina Tinel, Michel Maratrat, Gerard Feldmann, Anne-Marie Durand-Schneider, J. Loeper, Marie-Anne Robin, Philippe Beaune, F. Ballet, Dominique Pessayre
Publikováno v:
Gastroenterology. 108:1110-1123
Background/Aims: Autoantibodies against cytochrome P450 are found in some forms of autoimmune hepatitis. Cytochrome P450 is synthesized and mainly located in the endoplasmic reticulum but may also be expressed on the plasma membrane of hepatocytes. V
Autor:
Isabelle Larosche, Marie-Anne Robin, Sophie C. Cazanave, Nathalie Vadrot, Marina Tinel, Dominique Pessayre, Philippe Lettéron, Gérard Feldmann, Véronique Descatoire, Alain Berson
Publikováno v:
Toxicology and applied pharmacology. 231(3)
Fas stimulation recruits neutrophils and activates macrophages that secrete tumor necrosis factor-alpha (TNF-alpha), which aggravates Fas-mediated liver injury. To determine whether nonsteroidal anti-inflammatory drugs modify these processes, we chal
Autor:
Philippe Lettéron, Jacques Belghiti, Dominique Larrey, Marina Tinel, J. Loeper, Patrick Maurel, Dominique Pessayre
Publikováno v:
Biochemical Pharmacology. 40:545-550
Incubation of [ 14 C]tianeptine (0.5 mM) with human liver microsomes and a NADPH-generating system resulted in the in vitro covalent binding of a tianeptine metabolite to microsomal proteins. This covalent binding required oxygen and NADPH. It was de
Autor:
Marina Tinel, Philippe Beaune, Alain Berson, Johny Elkahwaji, Dominique Pessayre, Thierry Cresteil
Publikováno v:
Journal of hepatology. 39(2)
Background/Aims : Several cytochromes P450 (CYPs) are expressed in differentiated hepatocytes, but downregulated in growth-stimulated cells. We determined the signals involved in CYP downregulation by epidermal growth factor (EGF). Methods : Rat hepa
Autor:
Claude Degott, Caroline Maisonneuve, Richard Nguyen, Alain Grodet, Marina Tinel, Christine Demeilliers, Dominique Pessayre, Bernard Fromenty, Philippe Lettéron, Abdellah Mansouri, Gérard Feldmann
Publikováno v:
Gastroenterology
Gastroenterology, 2002, 123 (4), pp.1278-1290. ⟨10.1053/gast.2002.35952⟩
Gastroenterology, WB Saunders, 2002, 123 (4), pp.1278-1290. ⟨10.1053/gast.2002.35952⟩
Gastroenterology, 2002, 123 (4), pp.1278-1290. ⟨10.1053/gast.2002.35952⟩
Gastroenterology, WB Saunders, 2002, 123 (4), pp.1278-1290. ⟨10.1053/gast.2002.35952⟩
Background & Aims: A single dose of alcohol causes transient hepatic mitochondrial DNA (mtDNA) depletion in mice followed by increased mtDNA synthesis and an overshoot of mtDNA levels. We determined the effect of repeated alcohol binges on hepatic mt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badbfc7596e326449653c82513e94c99
https://hal.science/hal-02185534
https://hal.science/hal-02185534
Autor:
Mounia Lekehal, Gérard Feldmann, Nathalie Vadrot, Delphine Haouzi, Marina Tinel, Alain Moreau, Dominique Pessayre, Philippe Lettéron, Laure Caussanel, Daniel Fau
Publikováno v:
Hepatology
Hepatology, Wiley-Blackwell, 2001, 33, pp.1181-1188. ⟨10.1053/jhep.2001.24235⟩
Hepatology, Wiley-Blackwell, 2001, 33, pp.1181-1188. ⟨10.1053/jhep.2001.24235⟩
Glutathione depletion either decreased or increased death-receptor–mediated apoptosis in previous studies. Comparison of the durations of glutathione depletion before death-receptor stimulation in these studies might suggest a different effect of p
Autor:
Marie-Pierre Junier, Marina Tinel, Alexander G. Rabchevsky, Juno M. Weinitz, Muriel Coulpier, C. Fages
Publikováno v:
HAL
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 1998, 18 (24), pp.10541-10552
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 1998, 18 (24), pp.10541-10552
International audience; TGFalpha is a member of the epidermal growth factor (EGF) family with which it shares the same receptor, the EGF receptor (EGFR). Synthesis of TGFalpha and EGFR in reactive astrocytes developing after CNS insults is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2cce40066b1606dae5fcdfde67e958
https://hal.inrae.fr/hal-02696118
https://hal.inrae.fr/hal-02696118