Cell-Promoted Nanoparticle Aggregation Decreases Nanoparticle-Induced Hyperthermia under an Alternating Magnetic Field Independently of Nanoparticle Coating, Core Size, and Subcellular Localization

Autor: Patricia Hernández Flores, Raquel Mejías, José L Tajada-Herráiz, Marina Talelli, María del Puerto Morales, Domingo F. Barber, Maria Eugênia Fortes Brollo, Yadileiny Portilla

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Magnetic hyperthermia has a significant potential to be a new breakthrough for cancer treatment. The simple concept of nanoparticle-induced heating by the application of an alternating magnetic field has attracted much attention, as it allows the loc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417da0193ba6c6c81a55c475d41d093a
http://hdl.handle.net/10261/191989

Time-course assessment of the aggregation and metabolization of magnetic nanoparticles

Autor: Vanesa del Dedo, Eduardo Lorente-Sorolla, Laura Sanz-Ortega, José M. Rojas, Rocío Costo, Lucía Gutiérrez, Sonia Pérez-Yagüe, Marina Talelli, Domingo F. Barber, M. Puerto Morales, Gustavo B. da Silva, Helena Gavilán, Marzia Marciello

Publikováno v: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
Digital.CSIC. Repositorio Institucional del CSIC
instname
INIA: Repositorio de Resultados de Investigación del INIA

To successfully develop biomedical applications for magnetic nanoparticles, it is imperative that these nanoreagents maintain their magnetic properties in vivo and that their by-products are safely metabolized. When placed in biological milieu or int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41eef722f72db57444989dddcacd4447
https://hdl.handle.net/20.500.12792/3868

Polymeric micelles for cancer therapy: 3 C’s to enhance efficacy

Autor: Wim E. Hennink, Cristianne J.F. Rijcken, Marina Talelli, Twan Lammers

Publikováno v: Current Opinion in Solid State and Materials Science. 16:302-309

During the past few years, polymeric micelles (PM), which can accommodate various different hydrophobic anticancer agents within their core, have received substantial attention as EPR-targeted drug delivery systems for cancer therapy. PM can be modif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d56954d4f56f5bf42b90086619da3926
https://doi.org/10.1016/j.cossms.2012.10.003

Design of thermoresponsive polymeric gates with opposite controlled release behaviors

Autor: María Vallet-Regí, Eduardo Guisasola, Marina Talelli, Daniel Arcos, Alejandro Baeza

Publikováno v: E-Prints Complutense. Archivo Institucional de la UCM
instname
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid

Stimuli-responsive devices are novel tools widely studied in the nanomedicine research field. In this work, magnetic-responsive mesoporous silica nanoparticles (MMSNs) were coated with an engineered thermoresponsive co-polymer. Magnetic cores are use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f751cbb365d3cf64e6180df02f5028ca
http://eprints.ucm.es/41692/

Synthesis and Characterization of Biodegradable and Thermosensitive Polymeric Micelles with Covalently Bound Doxorubicin-Glucuronide Prodrug via Click Chemistry

Autor: Cristianne J.F. Rijcken, C.F. van Nostrum, Gert Storm, Hans W. Scheeren, K. Morita, Marina Talelli, Twan Lammers, Wim E. Hennink, R. W. M. Aben

Publikováno v: Bioconjugate Chemistry. 22:2519-2530

Doxorubicin is an anthracycline anticancer agent that is commonly used in the treatment of a variety of cancers, but its application is associated with severe side effects. Biodegradable and thermosensitive polymeric micelles based on poly(ethylene g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41567cbcef17c0907ae4075a1eb0c332
https://doi.org/10.1021/bc2003499