Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marina Svicevic"'
Autor:
Djordje Nedic, Henk Granzier, Srboljub M. Mijailovich, Michael A. Geeves, Thomas C. Irving, Marina Svicevic, Boban Stojanovic
Publikováno v:
The Journal of General Physiology
The contractility of striated muscle can be modulated by various mutations in nebulin and titin present in human disease. Mijailovich et al. perform computational simulations coupled with experimental observations to provide insights into the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5bea5acb8014ed2a14ece2d79910a4
http://europepmc.org/articles/PMC6504291
http://europepmc.org/articles/PMC6504291
Autor:
Milos Ivanovic, Ana Kaplarevic-Malisic, Srboljub M. Mijailovich, Marina Svicevic, Boban Stojanovic
Publikováno v:
The International Journal of High Performance Computing Applications. 33:885-896
Since multi-scale models of muscles rely on the integration of physical and biochemical properties across multiple length and time scales, they are highly processor and memory intensive. Consequently, their practical implementation and usage in real-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99bc996d3b375558579cc0b6747d8cda
https://doi.org/10.1177/1094342019833151
https://doi.org/10.1177/1094342019833151
Publikováno v:
International Journal of Numerical Methods for Heat & Fluid Flow. 27:2682-2695
Purpose The purpose of this paper is to improve the accuracy and stability of the existing solutions to 1D Stefan problem with time-dependent Dirichlet boundary conditions. The accuracy improvement should come with respect to both temperature distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ada6cf2239b05c7ac6b6212c57730e
https://doi.org/10.1108/hff-11-2016-0443
https://doi.org/10.1108/hff-11-2016-0443
Autor:
Leslie A. Leinwand, Marina Svicevic, Anastasia Karabina, Chloe A. Johnson, Michael A. Geeves, Srboljub M. Mijailovich, Jonathan Walklate, Carlos Vera
Publikováno v:
J Biol Chem
Striated muscle myosins are encoded by a large gene family in all mammals, including humans. These isoforms define several of the key characteristics of the different striated muscle fiber types, including maximum shortening velocity. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07a81f0e9d83e5b5a76259dcc343873
https://pubmed.ncbi.nlm.nih.gov/31387944
https://pubmed.ncbi.nlm.nih.gov/31387944
Autor:
Milovan Milivojevic, Srboljub Mijailovic, Milos Ivanovic, Boban Stojanovic, Ana Kaplarevic-Malisic, Djordje Nedic, Marina Svicevic, Nikola Milivojević, Visnja Simic
Publikováno v:
Journal of Serbian Society for Computational Mechanics (2016) 10(1):34-49
In previous decades a number of computational methods for calculation of very complex physical phenomena with a satisfactory accuracy have been developed. Most of these methods usually model only a single physical phenomenon, while their performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083f6eea72baad90b19b9e1eab0b1b92
https://doi.org/10.5937/jsscm1601034s
https://doi.org/10.5937/jsscm1601034s
Autor:
Richard J. Gilbert, Boban Stojanovic, Marina Svicevic, Ana Kaplarevic-Malisic, Srboljub M. Mijailovich
Publikováno v:
Journal of Computational Science
The investigation of healthy and diseased muscle behavior via in silico analysis requires the modeling of biophysical processes on multiple spatial and temporal scales. Owing to the complexity of the phenomena in question, simultaneous simulations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860a359b1a46e3ca098782fdcd29a055
https://doi.org/10.1016/j.jocs.2019.101062
https://doi.org/10.1016/j.jocs.2019.101062
Autor:
Leslie A. Leinwand, Masataka Kawana, Elizabeth Choe Yu, Kathleen M. Ruppel, Marina Svicevic, Carlos Vera, Srbolujub M. Mijailovich, Michael A. Geeves, James A. Spudich, Zoltan Ujfalusi
Dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) can cause arrhythmias, heart failure, and cardiac death. Here, we functionally characterized the motor domains of five DCM-causing mutations in human β-cardiac myosin. Kinetic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d6e19edeaa92f6cb261ba85a21c9f0
Autor:
Djordje Nedic, Srbolujub M. Mijailovich, Boban Stojanovic, Zoltan Ujfalusi, Jonathan Walklate, Michael A. Geeves, Marina Svicevic
Publikováno v:
Biophysical journal. 112(5)
Modeling the complete actin.myosin ATPase cycle has always been limited by the lack of experimental data concerning key steps of the cycle, because these steps can only be defined at very low ionic strength. Here, using human β-cardiac myosin-S1, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0870366e4dd3c7592155c27dd0583a7
https://pubmed.ncbi.nlm.nih.gov/28297657
https://pubmed.ncbi.nlm.nih.gov/28297657
Autor:
Boban Stojanovic, Srboljub M. Mijailovich, Djordje Nedic, Michael A. Geeves, Michael Regnier, Marina Svicevic
Publikováno v:
Biophysical Journal. 110(3)
Predicting the dynamic behaviour of a muscle fibre containing a heterogeneous mixture of isoforms (e.g. fast and slow isoforms mutant and wt protein) is difficult since responses may be non-linear. We have implemented in a computational platform MUSI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac89d8aa84ad53d9afa5b4b014dc603c
Autor:
Leslie A. Leinwand, Srbolujub M. Mijailovich, Carlos Vera, Michael A. Geeves, Marina Svicevic, Zoltan Ujfalusi
Publikováno v:
Biophysical Journal. 114:210a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5604c496c27dcc4ccd8616436e705460
https://doi.org/10.1016/j.bpj.2017.11.1178
https://doi.org/10.1016/j.bpj.2017.11.1178