Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Marina Skrygan"'
Autor:
Thilo Gambichler, Jonas Rüth, Silke Goesmann, Stefan Höxtermann, Marina Skrygan, Laura Susok, Jürgen C. Becker, Oliver Overheu, Wolfgang Schmidt, Anke Reinacher-Schick
Publikováno v:
Viruses, Vol 16, Iss 5, p 810 (2024)
In patients with COVID-19, broad panels of immune checkpoint molecules (ICPMs) and the purinergic signaling have not been studied in parallel. We aimed to perform in-depth immunophenotyping of major cell subsets present in human peripheral blood of C
Externí odkaz:
https://doaj.org/article/878c6a3945914e50a4b3dfc8f93469e1
Autor:
Milan Barras, Lutz Schmitz, Chris Braumann, Waldemar Uhl, Marina Skrygan, Marie Buchholz, Thomas Meyer, Eggert Stockfleth, Thomas Müller, Jürgen C. Becker, Thilo Gambichler
Publikováno v:
Dermato, Vol 3, Iss 1, Pp 85-96 (2023)
Advanced cutaneous squamous cell carcinoma (cSCC) can be a life-threatening disease for which effective and safe treatment in advanced stages is very limited. GP-2250 has been recently proven to have—in vitro and in vivo—antineoplastic effects on
Externí odkaz:
https://doaj.org/article/177e1cb6819e4d4dbc50587f72c8654d
Autor:
Thilo Gambichler, Friederike Harnischfeger, Marina Skrygan, Britta Majchrzak-Stiller, Marie Buchholz, Thomas Müller, Chris Braumann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15336 (2023)
Enhanced glycolysis (Warburg effect) driven by the BRAF oncogene, dysregulated GAPDH expression, and activation of the PI3K/AKT/mTOR signaling pathway may significantly contribute to the resistance-targeted therapy of BRAF-mutated melanomas. Therefor
Externí odkaz:
https://doaj.org/article/c407409a07a4479d80c656c150d8662f
Autor:
Thilo Gambichler, Nomun Ganjuur, Andrea Tannapfel, Markus Vogt, Lisa Scholl, Nessr Abu Rached, Stefanie Bruckmüller, Marina Skrygan, Jürgen C. Becker, Heiko U. Käfferlein, Thomas Brüning, Kerstin Lang
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3316-3322 (2021)
There exist relatively sparse and conflicting data on high-level microsatellite instability (MSI-H) and deficient mismatch repair (dMMR) in cutaneous malignancies. We aimed to determine the expression profiles of MMR proteins (MSH2, MSH6, MLH1, and P
Externí odkaz:
https://doaj.org/article/ccad12df51d149358f3ee99d9de685d7
Autor:
Thilo Gambichler, Lyn G. Brüggestrat, Marina Skrygan, Christina H. Scheel, Laura Susok, Jürgen C. Becker
Publikováno v:
Cancers, Vol 15, Iss 2, p 547 (2023)
Merkel cell carcinoma (MCC) is a rare, difficult-to-treat skin cancer once immunotherapy has failed. MCC is associated either with the clonal integration of the Merkel cell polyomavirus (MCPyV) or mutagenic UV-radiation. Fumaric acid esters, includin
Externí odkaz:
https://doaj.org/article/cf6e38e4d325473fa0f596d8837be56a
Autor:
Thilo Gambichler, Nessr Abu Rached, Andrea Tannapfel, Jürgen C. Becker, Markus Vogt, Marina Skrygan, Ulrike Wieland, Steffi Silling, Laura Susok, Markus Stücker, Thomas Meyer, Eggert Stockfleth, Klaus Junker, Heiko U. Käfferlein, Thomas Brüning, Kerstin Lang
Publikováno v:
Cancers, Vol 13, Iss 11, p 2524 (2021)
We aimed to assess for the first time the mismatch repair (MMR) protein expression in Merkel cell carcinoma (MCC). Immunohistochemistry was performed for MLH1, MSH2, MSH6, and PMS2 on patients’ tumor tissue (n = 56), including neighbored healthy co
Externí odkaz:
https://doaj.org/article/4223a99545354838ade179f259bbce8b
Publikováno v:
Cancers, Vol 13, Iss 9, p 2090 (2021)
To date, the skin remains the most common cancer site among Caucasians in the western world. The complex, layered structure of human skin harbors a heterogenous population of specialized cells. Each cell type residing in the skin potentially gives ri
Externí odkaz:
https://doaj.org/article/d27715dc30b9498f9a7acf4b4e630ad6
Publikováno v:
Advances in Dermatology and Allergology, Vol 34, Iss 4, Pp 299-305 (2017)
Introduction: Apart from neutrophils, other immune cells may play a significant pathogenetic role in cutaneous leukocytoclastic vasculitis (CLV). Aim: To investigate lymphocytes and related immunological factors in patients with CLV requiring systemi
Externí odkaz:
https://doaj.org/article/1c88e5f6eded457ca7d27140eaa9ec83
Autor:
Thilo Gambichler, Silke Goesmann, Vera Korte, Marina Skrygan, Friederike Harnischfeger, Christina H Scheel, Nazha Hamdani, Heidi Budde, Marcel Sieme, Jüergen C Becker, Wolfgang Schmidt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38a100a2be7d18281f59119460b0678
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151312569
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151312569
Autor:
Lisa Scholl, Heidi Budde, N. Abu Rached, Marcel Sieme, Heinrich Dickel, Martin Doerler, Nazha Hamdani, N. Ganjuur, B Behle, Thilo Gambichler, L Pfeiffer, Christina Scheel, Marina Skrygan, René Stranzenbach, Jürgen C. Becker, L. Ocker
Publikováno v:
The British Journal of Dermatology
Dear Editor, Growing evidence suggests that SARS‐CoV‐2 vaccination is associated with a variety of cutaneous reactions, also including autoimmune‐mediated conditions such as autoimmune blistering diseases such as bullous pemphigoid (BP).1,2 We