Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marina Shamis"'
Autor:
Fernando Albericio, Gerardo A. Acosta, Yoav Luxembourg, Prabhakar Cherkupally, Hortensia Rodríguez, Lidia Nieto-Rodriguez, Jan Spengler, Rafel Prohens, Marina Shamis, Ramon Subiros-Funosas, Sherine N. Khattab, Ayman El-Faham
Publikováno v:
European Journal of Organic Chemistry. 2013:6372-6378
Here we present a new formulation of the recently introduced OxymaPure additive for peptide bond formation, in which the N-hydroxylamine group is replaced by a potassium salt. The complete suppression of its acidity converts KOxyma into the most suit
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:1172-1175
Fast and convenient methods are required for the detection of novel catalysts. We have developed a new assay to allow direct visualization of retro-aldol retro-Michael catalytic activity and have demonstrated it with catalytic antibody 38C2. The assa
Publikováno v:
Angewandte Chemie. 117:726-730
Publikováno v:
Journal of the American Chemical Society. 126:1726-1731
Self-immolative dendrimers have recently been developed and introduced as a potential platform for a multi-prodrug. These unique structural dendrimers can release all of their tail units, through a self-immolative chain fragmentation, which is initia
Publikováno v:
Angewandte Chemie. 115:4632-4637
An appropriate dendrimer could be structur-allydesignedtoreleaseallofitstailmoleculeswithasinglecleavageeventatthedendrimer'score.Hereweproposethedesign and synthesis of a novel dendritic structure with atriggerthatcaninitiatethefragmentationoftheden
Publikováno v:
Inorganic Chemistry Communications. 4:177-179
Two trianionic amine triphenolate ligands are introduced and their isopropoxide Ti(IV) complexes synthesized. The two complexes are mononuclear and C3-symmetrical on the NMR timescale. High barriers to inversion ( ΔG ‡ >65 KJ mol −1 ) between th
Autor:
Doron Shabat, Marina Shamis
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 13(16)
Self-immolative dendrimers are a unique class of molecules that are able to disassemble upon undergoing a specific triggering reaction through domino-like fragmentations. We have designed and synthesized a novel AB(6) self-immolative dendritic adapto
Bacteriophages have been used for more than a century for (unconventional) therapy of bacterial infections, for half a century as tools in genetic research, for 2 decades as tools for discovery of specific target-binding proteins, and for nearly a de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a157c5bee1ff5d13dd795da6bbc4d5
https://europepmc.org/articles/PMC1479106/
https://europepmc.org/articles/PMC1479106/
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 10(11)
"Chemical adaptor systems" are molecules used to link different functionalities, based on unique reactivity that allows controlled fragmentation. Two different mechanistic reactivities were used to prepare chemical adaptor systems. The first is based
Autor:
Noam Shomron, Neta Pessah, Hong Xin, Gil Ast, Katherine S. Bowdish, Doron Shabat, Mika Reznik, Ferda Yantiri, Marina Shamis
Publikováno v:
Bioorganicmedicinal chemistry. 12(8)
Two new prodrugs of CPT were synthesized, based on carbamate linkages between the 20-hydroxy group of CPT and a linker designed to be enzymatically removed by either Penicillin-G-Amidase or catalytic antibody 38C2. Cell growth inhibition assays showe