Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marina Senek"'
Publikováno v:
Informatics in Medicine Unlocked, Vol 9, Iss C, Pp 11-17 (2017)
Objectives: The aim of this paper is to investigate whether a smartphone-based system can be used to quantify dexterity in Parkinson's disease (PD). More specifically, the aim was to develop data-driven methods to quantify and characterize dexterity
Externí odkaz:
https://doaj.org/article/1436fb37ea9d4f608d588dc89060bf8b
Publikováno v:
Journal of Parkinson's Disease. 10:1529-1534
Background: Levodopa/carbidopa intestinal gel (LCIG) infusion is an efficacious treatment of motor and non-motor fluctuations in people with Parkinson’s disease (PD). Real-life use of the treatment is not previously studied. Objective: The aims of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1759f905a022c085e24305ee215d87de
https://doi.org/10.3233/jpd-202114
https://doi.org/10.3233/jpd-202114
Publikováno v:
IEEE Journal of Biomedical and Health Informatics. 24:111-119
Parkinson's disease (PD) is a degenerative, progressive disorder of the central nervous system that mainly affects motor control. The aim of this study was to develop data-driven methods and test their clinimetric properties to detect and quantify PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96da6a1ca448714db908f62eacaffbdd
https://doi.org/10.1109/jbhi.2019.2898332
https://doi.org/10.1109/jbhi.2019.2898332
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Levodopa-entacapone-carbidopa intestinal gel (LECIG) provides continuous drug delivery through intrajejunal infusion. The aim of this study was to characterize the population pharmacokinetics of levodopa following LECIG and levodopa-carbidopa intesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b136d54adbab93f483406afeb38368c
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-430221
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-430221
Publikováno v:
European Journal of Clinical Pharmacology
Objectives Low dose, dispersible, levodopa/carbidopa microtablets with an automatic dose dispenser have been developed to facilitate individualized levodopa treatment. The aim of this study was to characterize the pharmacokinetics (PK) of levodopa an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d1200bdb9f706e08a34587d791bb09
https://doi.org/10.1007/s00228-018-2497-2
https://doi.org/10.1007/s00228-018-2497-2
Autor:
Radu Constantinescu, Jerker Westin, Sten-Magnus Aquilonius, Alexander Medvedev, Jack Spira, Mevludin Memedi, Fredrik Ohlsson, Håkan Askmark, Anders Ericsson, Filip Bergquist, Marina Senek, Dag Nyholm, Sara Lycke
Publikováno v:
European Journal of Clinical Pharmacology
Background Motor function assessments with rating scales in relation to the pharmacokinetics of levodopa may increase the understanding of how to individualize and fine-tune treatments. Objectives This study aimed to investigate the pharmacokinetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a50b078b8b14338cf00a8d683366a6
http://europepmc.org/articles/PMC5384948
http://europepmc.org/articles/PMC5384948
Publikováno v:
Movement Disorders. 32:283-286
BackgroundThe addition of oral entacapone to levodopa-carbidopa intestinal gel treatment leads to less conversion of levodopa to 3-O-methyldopa, thereby increasing levodopa plasma concentration. Th ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1714b856979b9e81f7df6e915c2ef3d9
https://doi.org/10.1002/mds.26855
https://doi.org/10.1002/mds.26855
Autor:
Dongni Johansson, Ilias Thomas, Jack Spira, Dag Nyholm, Filip Bergquist, Alexander Medvedev, Anders Johansson, Fredrik Ohlsson, Anders Ericsson, Mevludin Memedi, Marina Senek, Jerker Westin
Publikováno v:
Parkinsonismrelated disorders. 64
A treatment response objective index (TRIS) was previously developed based on sensor data from pronation-supination tests. This study aimed to examine the performance of TRIS for medication effects in a new population sample with Parkinson's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67453197098750af8fc45ec62ce286db
https://pubmed.ncbi.nlm.nih.gov/30935826
https://pubmed.ncbi.nlm.nih.gov/30935826
Autor:
Ilias, Thomas, Jerker, Westin, Moudud, Alam, Filip, Bergquist, Dag, Nyholm, Marina, Senek, Mevludin, Memedi
Publikováno v:
IEEE journal of biomedical and health informatics. 22(5)
The goal of this study was to develop an algorithm that automatically quantifies motor states (off, on, dyskinesia) in Parkinson's disease (PD), based on accelerometry during a hand pronation-supination test. Clinician's ratings using the Treatment R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42aa6d8850015645b3bc120c02ac243d
https://pubmed.ncbi.nlm.nih.gov/29989996
https://pubmed.ncbi.nlm.nih.gov/29989996
Publikováno v:
International journal of medical informatics. 112
Background and objective To achieve optimal effect with continuous infusion treatment in Parkinson’s disease (PD), the individual doses (morning dose and continuous infusion rate) are titrated by trained medical personnel. This study describes an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7653e0196c8e8c68fe61ed7fa6c87a6
https://pubmed.ncbi.nlm.nih.gov/29500011
https://pubmed.ncbi.nlm.nih.gov/29500011