Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marina Ruiz Grecco"'
Autor:
Cecilia Viviana Alvarado, María Fernanda Rubio, Pablo Nicolas Fernández Larrosa, Laura Carolina Panelo, Pablo Javier Azurmendi, Marina Ruiz Grecco, Giselle Astrid Martínez-Nöel, Mónica Alejandra Costas
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
RAC3 is a coactivator of glucocorticoid receptor and nuclear factor-κB (NF-κB) that is usually over-expressed in tumors and which also has important functions in the immune system. We investigated the role of the inflammatory response in the contro
Externí odkaz:
https://doaj.org/article/1f0b0417a8c6465f853a0c3f31924b5a
Autor:
Pablo N. Fernández Larrosa, Marina Ruiz Grecco, Cecilia V. Alvarado, Sabrina Micenmacher, Cristina Aguirre, Giselle Martínez Nöel, Mónica A. Costas, María Fernanda Rubio
Publikováno v:
Medicina (Buenos Aires), Vol 71, Iss 3, Pp 238-242 (2011)
Tanto la autofagia como la senescencia celular son procesos que, en principio, evitan el desarrollo tumoral impidiendo la proliferación de células dañadas. Sin embargo, la autofagia no siempre lleva a la muerte celular, sino que puede ser un mecan
Autor:
Cecilia V. Alvarado, Sabrina Micenmacher, Marina Ruiz Grecco, María F. Rubio, Nicolás Fernández Larrosa, Mónica A. Costas
Publikováno v:
Medicina (Buenos Aires), Vol 71, Iss 1, Pp 33-38 (2011)
RAC3 fue caracterizado originalmente como un coactivador de receptores nucleares que se encuentra en cantidades limitantes en células normales, aunque sobreexpresado en tumores y es además coactivador de NF-?B. Si bien se desconocen los mecanismos
Autor:
Giselle Astrid Martinez-Noel, Laura Panelo, Maria Fernanda Rubio, Marina Ruiz Grecco, Monica Alejandra Costas, Pablo Nicolas Fernandez Larrosa, Sabrina Micenmacher, Cecilia Viviana Alvarado
Publikováno v:
Cancer Sci
RAC3 is an oncogene naturally overexpressed in several tumors. Besides its role as coactivator, it can exert several protumoral cytoplasmic actions. Autophagy was found to act either as a tumor suppressor during the early stages of tumor development,
Autor:
Pablo N, Fernández Larrosa, Marina, Ruiz Grecco, Cecilia V, Alvarado, Sabrina, Micenmacher, Cristina, Aguirre, Giselle, Martínez Noel, Mónica A, Costas, María Fernanda, Rubio
Publikováno v:
Medicina. 71(3)
Autophagy and senescence are both processes that firstly avoid tumor development through the inhibition of proliferation of damaged cells. However, autophagy does not imply cell death, because it is also a mechanism of cell survival under stress cond
Autor:
Laura Carolina Panelo, Sabrina Mariel Micenmacher, Pablo N. Larrosa Fernandez, Maria Fernanda Rubio, Cecilia Viviana Alvarado, Marina Ruiz Grecco, Monica Alejandra Costas, Georgina Pamela Colo, Giselle M. A. Martínez-Noël
Publikováno v:
Biochimica et biophysica acta. 1823(6)
NF-κB regulates the expression of Cyclin D1 (CD1), while RAC3 is an NF-κB coactivator that enhances its transcriptional activity. In this work, we investigated the regulatory role of CD1 on NF-κB activity. We found that CD1 inhibits NF-κB transcr
Autor:
Cecilia V, Alvarado, Sabrina, Micenmacher, Marina, Ruiz Grecco, Maria F, Rubio, Nicolas, Fernandez Larrosa, Monica A, Costas
Publikováno v:
Medicina. 71(1)
RAC3 has been firstly characterized as a nuclear receptor coactivator that is found in limited amounts in normal cells, but is over-expressed in tumors and is also an NF-kB coactivator. Although the mechanisms involved in its over-expression are not
Autor:
Cecilia Viviana Alvarado, Marina Ruiz Grecco, Pablo Nicolas Fernandez Larrosa, Monica Alejandra Costas, Laura Carolina Panelo, Maria Fernanda Rubio, Giselle M. A. Martínez-Noël, Pablo Javier Azurmendi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
Highlights • The inflammatory response increases the expression of RAC3 in vitro and in vivo. • TNF induces the increase of RAC3 at transcriptional level through NF-κB activation. • Glucocorticoids also induce the increase of RAC3 expression l