Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marina Roy Luzarraga"'
Autor:
Francesca R. Delvecchio, Rachel E.A. Fincham, Sarah Spear, Andrew Clear, Marina Roy-Luzarraga, Frances R. Balkwill, John G. Gribben, Michele Bombardieri, Kairbaan Hodivala-Dilke, Melania Capasso, Hemant M. Kocher
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)
Background and aims: The presence of tertiary lymphoid structures (TLSs) may confer survival benefit to patients with pancreatic ductal adenocarcinoma (PDAC), in an otherwise immunologically inert malignancy. Yet, the precise role in PDAC has not bee
Externí odkaz:
https://doaj.org/article/b635dee8c698441ab3175efcb13b1c08
Autor:
Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S. H. Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E. Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie Baker, Marina Roy-Luzarraga, Trevor A. Graham, Julie Foster, Yu Wang, James J. Campbell, Rajinder Singh, Penglie Zhang, Thomas J. Schall, Frances R. Balkwill, Jane Sosabowski, Pedro R. Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Cancer associated fibroblasts (CAFs) have been suggested to regulate cancer cell metabolism, but the mechanisms are not completely elucidated. Here, the authors show that low FAK expression in stromal cells correlates with poor prognosis in breast an
Externí odkaz:
https://doaj.org/article/514da35f7c834a7f879f285d226a9e53
Autor:
Marina Roy-Luzarraga, Louise E. Reynolds, Beatriz de Luxán-Delgado, Oscar Maiques, Laura Wisniewski, Emma Newport, Vinothini Rajeeve, Rebecca J.G. Drake, Jesús Gómez-Escudero, Frances M. Richards, Céline Weller, Christof Dormann, Ya-Ming Meng, Peter B. Vermeulen, Dieter Saur, Victoria Sanz-Moreno, Ping-Pui Wong, Cyrill Géraud, Pedro R. Cutillas, Kairbaan Hodivala-Dilke
Publikováno v:
Cancer Research. 82:1909-1925
Despite substantial advances in the treatment of solid cancers, resistance to therapy remains a major obstacle to prolonged progression-free survival. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with a high level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae75c56f3ed1498303615cd01969fa15
https://doi.org/10.1158/0008-5472.can-20-3807
https://doi.org/10.1158/0008-5472.can-20-3807
Autor:
Kairbaan Hodivala-Dilke, Pedro R. Cutillas, Cyrill Géraud, Ping-Pui Wong, Victoria Sanz-Moreno, Dieter Saur, Peter B. Vermeulen, Ya-Ming Meng, Christof Dormann, Céline Weller, Frances M. Richards, Jesús Gómez-Escudero, Rebecca J.G. Drake, Vinothini Rajeeve, Emma Newport, Laura Wisniewski, Oscar Maiques, Beatriz de Luxán-Delgado, Louise E. Reynolds, Marina Roy-Luzarraga
Supplementary Data from Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6fbefb5bd893c63c43ec853b8f0ac9
https://doi.org/10.1158/0008-5472.22430214.v1
https://doi.org/10.1158/0008-5472.22430214.v1
Autor:
Kairbaan Hodivala-Dilke, Pedro R. Cutillas, Cyrill Géraud, Ping-Pui Wong, Victoria Sanz-Moreno, Dieter Saur, Peter B. Vermeulen, Ya-Ming Meng, Christof Dormann, Céline Weller, Frances M. Richards, Jesús Gómez-Escudero, Rebecca J.G. Drake, Vinothini Rajeeve, Emma Newport, Laura Wisniewski, Oscar Maiques, Beatriz de Luxán-Delgado, Louise E. Reynolds, Marina Roy-Luzarraga
Despite substantial advances in the treatment of solid cancers, resistance to therapy remains a major obstacle to prolonged progression-free survival. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with a high level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda4b98719c7b41db9c381a53b02befb
https://doi.org/10.1158/0008-5472.c.6513567.v1
https://doi.org/10.1158/0008-5472.c.6513567.v1
Autor:
Kairbaan Hodivala-Dilke, Pedro R. Cutillas, Cyrill Géraud, Ping-Pui Wong, Victoria Sanz-Moreno, Dieter Saur, Peter B. Vermeulen, Ya-Ming Meng, Christof Dormann, Céline Weller, Frances M. Richards, Jesús Gómez-Escudero, Rebecca J.G. Drake, Vinothini Rajeeve, Emma Newport, Laura Wisniewski, Oscar Maiques, Beatriz de Luxán-Delgado, Louise E. Reynolds, Marina Roy-Luzarraga
Supplementary Figure from Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175e0f6375823c8293a0ca1880258164
https://doi.org/10.1158/0008-5472.22430202.v1
https://doi.org/10.1158/0008-5472.22430202.v1
Autor:
Delphine M. Lees, Louise E. Reynolds, Kairbaan Hodivala-Dilke, Ana Rita Pedrosa, Marina Roy-Luzarraga
Publikováno v:
Angiogenesis. 24:483-487
A correction to this paper has been published: https://doi.org/10.1007/s10456-021-09802-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d1987b883b3dad8590ab0b6b9eac686
https://doi.org/10.1007/s10456-021-09802-9
https://doi.org/10.1007/s10456-021-09802-9
Autor:
Kairbaan Hodivala-Dilke, Melania Capasso, Frances R. Balkwill, Hemant M. Kocher, Michele Bombardieri, Sarah Spear, Francesca R. Delvecchio, Andrew Clear, Rachel Elizabeth Ann Fincham, Marina Roy-Luzarraga, John G. Gribben
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology 12(5), 1543-1565 (2021). doi:10.1016/j.jcmgh.2021.06.023
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)
Cellular and Molecular Gastroenterology and Hepatology 12(5), 1543-1565 (2021). doi:10.1016/j.jcmgh.2021.06.023
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)
Background and aims The presence of tertiary lymphoid structures (TLSs) may confer survival benefit to patients with pancreatic ductal adenocarcinoma (PDAC), in an otherwise immunologically inert malignancy. Yet, the precise role in PDAC has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbca100680dfb1efb8c0cbafa14981d0
http://europepmc.org/articles/PMC8529396
http://europepmc.org/articles/PMC8529396
Autor:
Louise E. Reynolds, Ana Rita Pedrosa, Kairbaan Hodivala-Dilke, Marina Roy-Luzarraga, Delphine M. Lees
Publikováno v:
Angiogenesis
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that is overexpressed in many cancer types and in vivo studies have shown that vascular endothelial cell FAK expression and FAK-phosphorylation at tyrosine (Y) 397, and subsequently FAK-Y8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f0fd193a8c2712f909ca0fd8455efb
http://europepmc.org/articles/PMC8292267
http://europepmc.org/articles/PMC8292267
Autor:
Manish Patel, Kathleen N. Moore, Desiree Piscitello, Jayesh Majithiya, Marina Roy Luzarraga, Helen Millward, Sarah V. Holt, Melissa Johnson
Publikováno v:
Cancer Research. 82:LB520-LB520
Inhibition of ataxia telangiectasia and Rad-3 related (ATR) kinase offers therapeutic promise for DNA damage response deficient tumors. In addition, ATR inhibitors may offer even broader clinical utility when combined with PARPi’s, chemo, immune or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8339b39988ac45f52409a44d9375f61f
https://doi.org/10.1158/1538-7445.am2022-lb520
https://doi.org/10.1158/1538-7445.am2022-lb520