Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Marina R, Picciotto"'
Autor:
Prithviraj Rajebhosale, Mala R Ananth, Ronald Kim, Richard Crouse, Li Jiang, Gretchen López-Hernández, Chongbo Zhong, Christian Arty, Shaohua Wang, Alice Jone, Niraj S Desai, Yulong Li, Marina R Picciotto, Lorna W Role, David A Talmage
Publikováno v:
eLife, Vol 13 (2024)
Neurons of the basal forebrain nucleus basalis and posterior substantia innominata (NBM/SIp) comprise the major source of cholinergic input to the basolateral amygdala (BLA). Using a genetically encoded acetylcholine (ACh) sensor in mice, we demonstr
Externí odkaz:
https://doaj.org/article/933517eea9704773a9ceaadd7c9dff9a
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106745- (2023)
Human epidemiological studies have identified links between nicotine intake and stress disorders, including anxiety, depression and PTSD. Here we review the clinical evidence for activation and desensitization of nicotinic acetylcholine receptors (nA
Externí odkaz:
https://doaj.org/article/445ddf87ca26496686d98dfc121af820
Autor:
Takahiro Horie, Tetsushi Nakao, Yui Miyasaka, Tomohiro Nishino, Shigenobu Matsumura, Fumiko Nakazeki, Yuya Ide, Masahiro Kimura, Shuhei Tsuji, Randolph Ruiz Rodriguez, Toshimitsu Watanabe, Tomohiro Yamasaki, Sijia Xu, Chiharu Otani, Sawa Miyagawa, Kazuki Matsushita, Naoya Sowa, Aoi Omori, Jin Tanaka, Chika Nishimura, Masataka Nishiga, Yasuhide Kuwabara, Osamu Baba, Shin Watanabe, Hitoo Nishi, Yasuhiro Nakashima, Marina R. Picciotto, Haruhisa Inoue, Dai Watanabe, Kazuhiro Nakamura, Tsutomu Sasaki, Takeshi Kimura, Koh Ono
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Adaptive thermogenesis is regulated by central neuronal circuits. Here, the authors show that microRNA-33 in the brain contributes to the maintenance of brown adipose tissue thermogenesis and whole-body energy balance via enhanced sympathetic nerve t
Externí odkaz:
https://doaj.org/article/8523a0051c014923987d8a460a8d8a1f
Autor:
Angela M. Lee, Mohammad Shahid Mansuri, Rashaun S. Wilson, TuKiet T. Lam, Angus C. Nairn, Marina R. Picciotto
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Sex differences in behaviors relevant to nicotine addiction have been observed in rodent models and human subjects. Behavioral, imaging, and epidemiological studies also suggest underlying sex differences in mesolimbic dopamine signaling pathways. In
Externí odkaz:
https://doaj.org/article/651d3f1b6b1a4afc8a961a24277a5ab7
Autor:
Richard B Crouse, Kristen Kim, Hannah M Batchelor, Eric M Girardi, Rufina Kamaletdinova, Justin Chan, Prithviraj Rajebhosale, Steven T Pittenger, Lorna W Role, David A Talmage, Miao Jing, Yulong Li, Xiao-Bing Gao, Yann S Mineur, Marina R Picciotto
Publikováno v:
eLife, Vol 9 (2020)
The basolateral amygdala (BLA) is critical for associating initially neutral cues with appetitive and aversive stimuli and receives dense neuromodulatory acetylcholine (ACh) projections. We measured BLA ACh signaling and activity of neurons expressin
Externí odkaz:
https://doaj.org/article/223c36eed54e48cfb39c272f2a9258c7
Autor:
Yann S. Mineur, Tenna N. Mose, Kathrine Lefoli Maibom, Steven T. Pittenger, Alexa R. Soares, Hao Wu, Seth R. Taylor, Yaqing Huang, Marina R. Picciotto
Publikováno v:
Molecular Psychiatry. 27:4918-4927
Publikováno v:
Neuropsychopharmacology.
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract While exposure to nicotine during developmental periods can significantly affect brain development, studies examining the association between maternal smoking and autism spectrum disorder (ASD) in offspring have produced conflicting findings
Externí odkaz:
https://doaj.org/article/9c60e775136245069ec4c695fbdd24f0
Autor:
MacKenzie R. Peltier, Terril L. Verplaetse, Yann S. Mineur, Ismene L. Petrakis, Kelly P. Cosgrove, Marina R. Picciotto, Sherry A. McKee
Publikováno v:
Neurobiology of Stress, Vol 10, Iss , Pp - (2019)
Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten years relative to a 35% increase in men. This substantive increase in female drinking is alarming given that women experience greater alcohol-related health conseque
Externí odkaz:
https://doaj.org/article/f2117bafe92f459189027754e39fb12c
Autor:
Boyoung Lee, Santosh Pothula, Min Wu, Hyeyeon Kang, Matthew J. Girgenti, Marina R. Picciotto, Ralph J. DiLeone, Jane R. Taylor, Ronald S. Duman
Publikováno v:
Molecular Psychiatry. 27:2580-2589
N-methyl-D-aspartate receptor (NMDAR) modulators have recently received increased attention as potential therapeutics for posttraumatic stress disorder (PTSD). Here, we tested a novel NMDAR-positive modulator, NYX-783, in the following two rodent mod