Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marina Nura Raie"'
Autor:
Jai Woong Seo, Javier Ajenjo, Bo Wu, Elise Robinson, Marina Nura Raie, James Wang, Spencer K. Tumbale, Pablo Buccino, David Alexander Anders, Bin Shen, Frezghi G. Habte, Corinne Beinat, Michelle L. James, Samantha Taylor Reyes, Sripriya Ravindra Kumar, Timothy F. Miles, Jason T. Lee, Viviana Gradinaru, Katherine W. Ferrara
Publikováno v:
Biomaterials. 288
The development of gene delivery vehicles with high organ specificity when administered systemically is a critical goal for gene therapy. We combine optical and positron emission tomography (PET) imaging of 1) reporter genes and 2) capsid tags to ass
Autor:
Spencer K. Tumbale, R. Holland Cheng, Elizabeth S. Ingham, Wei-Lun Tang, Sarah M. Tam, Bo Wu, Alexander D. Borowsky, Katherine W. Ferrara, Mo Baikoghli, Marina Nura Raie, Brett Z. Fite, Josquin Foiret, Azadeh Kheirolomoom, Lisa M. Mahakian, Hua Zhang, Kenneth Lau
Publikováno v:
J Control Release
Resiquimod (R848) is a toll-like receptor 7 and 8 (TLR7/8) agonist with potent antitumor and immunostimulatory activity. However, systemic delivery of R848 is poorly tolerated because of its poor solubility in water and systemic immune activation. In
Autor:
Pei Liu, Azadeh Kheirolomoom, Spencer K. Tumbale, Marina Nura Raie, Katherine W. Ferrara, Bo Wu, Zhifei Dai, Nisi Zhang, James Wang, Yi Feng, Brett Z. Fite, Josquin Foiret
Publikováno v:
Adv Ther (Weinh)
Immunotherapy is an important cancer treatment strategy; nevertheless, the lack of robust immune cell infiltration in the tumor microenvironment remains a factor in limiting patient response rates. In vivo gene delivery protocols can amplify immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c55a85af038a7643eaffe5e04a0930
https://europepmc.org/articles/PMC8494128/
https://europepmc.org/articles/PMC8494128/
Autor:
Elizabeth S. Ingham, Marina Nura-Raie, Katherine W. Ferrara, Sarah M. Tam, Azadeh Kheirolomoom, Jamal S. Lewis, Hamilton Kakwere, Asaf Ilovitsh, Riley Allen, Brett Z. Fite, Spencer K. Tumbale, Bo Wu, Hua Zhang, Cheng Liu
Publikováno v:
Adv Healthc Mater
Advanced healthcare materials, vol 10, iss 10
Advanced healthcare materials, vol 10, iss 10
Resiquimod is an immunopotent toll-like receptor 7/8 agonist with antitumor activity. Despite being potent against skin cancers, it is poorly tolerated systemically due to toxicity. Integrating resiquimod into nanoparticles presents an avenue to circ
Autor:
Bo Wu, Aris J Kare, Marina Nura Raie, Spencer K. Tumbale, Katherine W. Ferrara, Sadaf Aghevlian, Jai Woong Seo
Publikováno v:
Nucl Med Biol
BACKGROUND: A novel [(64)Cu]Cu-NOTA-aCD40 immunoPET tracer was developed to image a CD40(+) pancreatic tumor model in C57BL/6 mice and to study the biodistribution profile of the agonist CD40 (aCD40) monoclonal antibody (mAb) alone or combined with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1b389417f290dfb04d55ec942f11b7
https://europepmc.org/articles/PMC8486004/
https://europepmc.org/articles/PMC8486004/
Autor:
Josquin Foiret, Spencer K. Tumbale, Lei S. Qi, Nisi Zhang, Ophir Vermesh, Elizabeth S. Ingham, Katherine W. Ferrara, Bo Wu, Michael Chavez, Asaf Ilovitsh, Marina Nura Raie, Dan Gazit, Aris J Kare, Gadi Pelled, Tali Ilovitsh, Yi Feng, Brett Z. Fite, Hua Zhang, Idan Steinberg, Azadeh Kheirolomoom, Sanjiv S. Gambhir
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 23
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Robust cytotoxic T cell infiltration has proven to be difficult to achieve in solid tumors. We set out to develop a flexible protocol to efficiently transfect tumor and stromal cells to produce immune-activating cytokines, and thus enhance T cell inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152eb4da5828ae719e6f2a66e4f5f6f6
https://escholarship.org/uc/item/7wn5813b
https://escholarship.org/uc/item/7wn5813b
Autor:
Spencer K. Tumbale, James Wang, Josquin Foiret, Pei Liu, Katherine W. Ferrara, Nisi Zhang, Yi Feng, Azadeh Kheirolomoom, Bo Wu, Brett Z. Fite, Marina Nura Raie, Zhifei Dai
Publikováno v:
Advanced Therapeutics. 4:2170020