Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Marina Naval Sanchez"'
Autor:
Delphine Potier, Kristofer Davie, Gert Hulselmans, Marina Naval Sanchez, Lotte Haagen, Vân Anh Huynh-Thu, Duygu Koldere, Arzu Celik, Pierre Geurts, Valerie Christiaens, Stein Aerts
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2290-2303 (2014)
Genome control is operated by transcription factors (TFs) controlling their target genes by binding to promoters and enhancers. Conceptually, the interactions between TFs, their binding sites, and their functional targets are represented by gene regu
Externí odkaz:
https://doaj.org/article/8692b193e7d141399ca4c856f3f95f0c
Autor:
Rekin's Janky, Annelien Verfaillie, Hana Imrichová, Bram Van de Sande, Laura Standaert, Valerie Christiaens, Gert Hulselmans, Koen Herten, Marina Naval Sanchez, Delphine Potier, Dmitry Svetlichnyy, Zeynep Kalender Atak, Mark Fiers, Jean-Christophe Marine, Stein Aerts
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 7, p e1003731 (2014)
Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. We developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network u
Externí odkaz:
https://doaj.org/article/709d0c14a614436cbd7be589f1fbc7a4
Autor:
Stein Aerts, Xiao-Jiang Quan, Annelies Claeys, Marina Naval Sanchez, Phillip Tate, Jiekun Yan, Bassem A Hassan
Publikováno v:
PLoS Biology, Vol 8, Iss 7, p e1000435 (2010)
A comprehensive systems-level understanding of developmental programs requires the mapping of the underlying gene regulatory networks. While significant progress has been made in mapping a few such networks, almost all gene regulatory networks underl
Externí odkaz:
https://doaj.org/article/cd19c781272241a2850d6f85798250d6
Autor:
Marta Gòdia, Yu Lian, Marina Naval-Sanchez, Inma Ponte, Joan Enric Rodríguez-Gil, Armand Sanchez, Alex Clop
Publikováno v:
PeerJ, Vol 11, p e15520 (2023)
The mammalian spermatozoon has a unique chromatin structure in which the majority of histones are replaced by protamines during spermatogenesis and a small fraction of nucleosomes are retained at specific locations of the genome. The sperm’s chroma
Externí odkaz:
https://doaj.org/article/f390a4b1d46d4d62bff1292baab7c855
Autor:
Marina Naval-Sanchez, Nikita Deshpande, Minh Tran, Jingyu Zhang, Majid Alhomrani, Walaa Alsanie, Quan Nguyen, Christian M. Nefzger
Publikováno v:
Frontiers in Molecular Biosciences. 9
Background: Chromatin falls into one of two major subtypes: closed heterochromatin and euchromatin which is accessible, transcriptionally active, and occupied by transcription factors (TFs). The most widely used approach to interrogate differences in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594a42c0244d2859fdda5f107ec38529
https://doi.org/10.3389/fmolb.2022.900323
https://doi.org/10.3389/fmolb.2022.900323
Autor:
Amin R, Mohamed, Marina, Naval-Sanchez, Moira, Menzies, Bradley, Evans, Harry, King, Antonio, Reverter, James W, Kijas
Publikováno v:
BMC Genomics. 23
Background Despite sexual development being ubiquitous to vertebrates, the molecular mechanisms underpinning this fundamental transition remain largely undocumented in many organisms. We designed a time course experiment that successfully sampled the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13211efa8d612eda9280b130b470eff
https://doi.org/10.1186/s12864-022-08514-8
https://doi.org/10.1186/s12864-022-08514-8
Autor:
Russell E. Lyons, Nicholas J. Hudson, Marina Naval-Sanchez, Antonio Reverter, Laercio R. Porto-Neto
Publikováno v:
Animal Genetics. 52:275-283
The Wagyu breed of taurine cattle possess favourable genetics for intramuscular fat (IMF) but genomic loci associated with the trait remain under characterised. Here, we report the identification of a previously unidentified genomic region possessing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3de602c734f086d82c95c9aed4e6c5e
https://doi.org/10.1111/age.13054
https://doi.org/10.1111/age.13054
Autor:
Dalia Mizikovsky, Marina Naval Sanchez, Christian M Nefzger, Gabriel Cuellar Partida, Nathan J Palpant
Publikováno v:
Nucleic acids research. 50(15)
Genome wide association studies provide statistical measures of gene–trait associations that reveal how genetic variation influences phenotypes. This study develops an unsupervised dimensionality reduction method called UnTANGLeD (Unsupervised Trai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647e0e375b1b080c11f1bb4184a553bc
https://pubmed.ncbi.nlm.nih.gov/35716123
https://pubmed.ncbi.nlm.nih.gov/35716123
Autor:
Moira Menzies, Antonio Reverter, Marina Naval-Sanchez, Pâmela A. Alexandre, Laercio R. Porto-Neto, Loan T. Nguyen, Marina R. S. Fortes
Publikováno v:
Genome Biology
Genome Biology, Vol 22, Iss 1, Pp 1-20 (2021)
Genome Biology, Vol 22, Iss 1, Pp 1-20 (2021)
BackgroundSpatiotemporal changes in the chromatin accessibility landscape are essential to cell differentiation, development, health, and disease. The quest of identifying regulatory elements in open chromatin regions across different tissues and dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2fdf74d45e5713ebfe9adf0849aec8
http://europepmc.org/articles/PMC8454054
http://europepmc.org/articles/PMC8454054
Autor:
Joan E. Rodríguez-Gil, Inma Ponte, Alex Clop, Marta Gòdia, Saher Sue Hammoud, Armand Sánchez, Marina Naval-Sanchez
BackgroundThe mammalian mature spermatozoon has a unique chromatin structure in which the vast majority of histones are replaced by protamines during spermatogenesis and a small fraction of nucleosomes are retained at specific locations of the genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655ca3cdba592568de78e15f202e6cc1
https://doi.org/10.1101/2021.03.30.437505
https://doi.org/10.1101/2021.03.30.437505
