Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Marina Naval Sanchez"'
Autor:
Marta Gòdia, Yu Lian, Marina Naval-Sanchez, Inma Ponte, Joan Enric Rodríguez-Gil, Armand Sanchez, Alex Clop
Publikováno v:
PeerJ, Vol 11, p e15520 (2023)
The mammalian spermatozoon has a unique chromatin structure in which the majority of histones are replaced by protamines during spermatogenesis and a small fraction of nucleosomes are retained at specific locations of the genome. The sperm’s chroma
Externí odkaz:
https://doaj.org/article/f390a4b1d46d4d62bff1292baab7c855
Autor:
Amin R. Mohamed, Marina Naval-Sanchez, Moira Menzies, Bradley Evans, Harry King, Antonio Reverter, James W. Kijas
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background Despite sexual development being ubiquitous to vertebrates, the molecular mechanisms underpinning this fundamental transition remain largely undocumented in many organisms. We designed a time course experiment that successfully sa
Externí odkaz:
https://doaj.org/article/5ec06f41079e4c07a192802de3d83efb
Autor:
Marina Naval-Sanchez, Nikita Deshpande, Minh Tran, Jingyu Zhang, Majid Alhomrani, Walaa Alsanie, Quan Nguyen, Christian M. Nefzger
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: Chromatin falls into one of two major subtypes: closed heterochromatin and euchromatin which is accessible, transcriptionally active, and occupied by transcription factors (TFs). The most widely used approach to interrogate differences in
Externí odkaz:
https://doaj.org/article/b58a43b3a3fd4314aa6a92be97d9c497
Autor:
Xuan Sun, Benjamin Cao, Marina Naval-Sanchez, Tony Pham, Yu Bo Yang Sun, Brenda Williams, Shen Y. Heazlewood, Nikita Deshpande, Jinhua Li, Felix Kraus, James Rae, Quan Nguyen, Hamed Yari, Jan Schröder, Chad K. Heazlewood, Madeline Fulton, Jessica Hatwell-Humble, Kaustav Das Gupta, Ronan Kapetanovic, Xiaoli Chen, Matthew J. Sweet, Robert G. Parton, Michael T. Ryan, Jose M. Polo, Christian M. Nefzger, Susan K. Nilsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Aged hematopoietic stem cells (HSC) are characterised by reduced regenerative potential and a loss of quiescence. Here, the authors show nicotinamide riboside treatment shrinks the age-enlarged stem cell pool and shifts aged HSC functionally, metabol
Externí odkaz:
https://doaj.org/article/a2cd09ff347c4623848c6acc6789d348
Autor:
Enakshi Sinniah, Zhixuan Wu, Sophie Shen, Marina Naval-Sanchez, Xiaoli Chen, Junxian Lim, Abbigail Helfer, Abishek Iyer, Jiahui Tng, Andrew J. Lucke, Robert C. Reid, Meredith A. Redd, Christian M. Nefzger, David P. Fairlie, Nathan J. Palpant
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110818- (2022)
Summary: Histone deacetylases (HDACs) are a class of enzymes that control chromatin state and influence cell fate. We evaluated the chromatin accessibility and transcriptome dynamics of zinc-containing HDACs during cell differentiation in vitro coupl
Externí odkaz:
https://doaj.org/article/ff2fec34f59f427e9e6f8bfee429eada
Autor:
Li Yieng Lau, Antonio Reverter, Nicholas J. Hudson, Marina Naval-Sanchez, Marina R. S. Fortes, Pâmela A. Alexandre
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Co-expression networks tightly coordinate the spatiotemporal patterns of gene expression unfolding during development. Due to the dynamic nature of developmental processes simply overlaying gene expression patterns onto static representations of co-e
Externí odkaz:
https://doaj.org/article/9596bfd5a7554ca4a070b813e4ad8d59
Autor:
Marina Naval-Sanchez, Sean McWilliam, Bradley Evans, José M. Yáñez, Ross D. Houston, James W. Kijas
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The introduction of wild Atlantic salmon into captivity, and their subsequent artificial selection for production traits, has caused phenotypic differences between domesticated fish and their wild counterparts. Identification of regions of the genome
Externí odkaz:
https://doaj.org/article/91ca0998a904433cab5b1d9cc007523b
Autor:
Marina Naval-Sanchez, Quan Nguyen, Sean McWilliam, Laercio R. Porto-Neto, Ross Tellam, Tony Vuocolo, Antonio Reverter, Miguel Perez-Enciso, Rudiger Brauning, Shannon Clarke, Alan McCulloch, Wahid Zamani, Saeid Naderi, Hamid Reza Rezaei, Francois Pompanon, Pierre Taberlet, Kim C. Worley, Richard A. Gibbs, Donna M. Muzny, Shalini N. Jhangiani, Noelle Cockett, Hans Daetwyler, James Kijas
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The domestication of plants and animals causes genomic changes underlying various morphologic, physiologic and behavioral changes. Here, Naval-Sanchez et al. provide a ChIP-Seq validated comparative functional annotation of the sheep genome, and show
Externí odkaz:
https://doaj.org/article/0d6d48e8263e4548bb656a5c037cedee
Autor:
Pâmela A. Alexandre, Marina Naval-Sanchez, Laercio R. Porto-Neto, José Bento S. Ferraz, Antonio Reverter, Heidge Fukumasu
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Systems biology approaches are used as strategy to uncover tissue-specific perturbations and regulatory genes related to complex phenotypes. We applied this approach to study feed efficiency (FE) in beef cattle, an important trait both economically a
Externí odkaz:
https://doaj.org/article/452e228981374add929db7f5385d85f9
Autor:
Delphine Potier, Kristofer Davie, Gert Hulselmans, Marina Naval Sanchez, Lotte Haagen, Vân Anh Huynh-Thu, Duygu Koldere, Arzu Celik, Pierre Geurts, Valerie Christiaens, Stein Aerts
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2290-2303 (2014)
Genome control is operated by transcription factors (TFs) controlling their target genes by binding to promoters and enhancers. Conceptually, the interactions between TFs, their binding sites, and their functional targets are represented by gene regu
Externí odkaz:
https://doaj.org/article/8692b193e7d141399ca4c856f3f95f0c