Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marina N. Torrero"'
Autor:
Cecilia B. Korol, Shamira J. Shallom, Kriti Arora, Helena I. Boshoff, Alexandra F. Freeman, Alejandra King, Sonia Agrawal, Sean C. Daugherty, Timothy Jancel, Juraj Kabat, Sundar Ganesan, Marina N. Torrero, Elizabeth P. Sampaio, Clifton Barry, Steve M Holland, Hervé Tettelin, Sergio D Rosenzweig, Adrian M. Zelazny
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1656-1673 (2020)
Summary: We characterized Mycobacterium bovis BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency. The isolates collected displayed distinct genomic and phenotypic features consistent with host ad
Externí odkaz:
https://doaj.org/article/c389e6b7ad754220ad0f5defb0a60810
Autor:
Adrian M. Zelazny, Kriti Arora, Elizabeth P. Sampaio, Timothy Jancel, Cecilia B. Korol, Alexandra F. Freeman, Shamira J. Shallom, Sean C. Daugherty, Marina N. Torrero, Sergio D. Rosenzweig, Hervé Tettelin, Sundar Ganesan, Sonia Agrawal, Clifton E. Barry, Alejandra King, Helena I. Boshoff, Steve M. Holland, Juraj Kabat
Publikováno v:
Virulence
article-version (VoR) Version of Record
Virulence, Vol 11, Iss 1, Pp 1656-1673 (2020)
article-version (VoR) Version of Record
Virulence, Vol 11, Iss 1, Pp 1656-1673 (2020)
Summary: We characterized Mycobacterium bovis BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency. The isolates collected displayed distinct genomic and phenotypic features consistent with host ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a060816f79b0b4e7d3e40b74fabb979
http://europepmc.org/articles/PMC7781554
http://europepmc.org/articles/PMC7781554
Autor:
Belinda M. Jackson-Thompson, Blima K. Mitre, Mathanraj Packiam, James Long, Marina N. Torrero, Edward Mitre
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss, Pp 100065-(2020)
Journal of Translational Autoimmunity
Journal of Translational Autoimmunity
Studies in humans and animals have demonstrated that infection with helminths (parasitic worms) is protective against a range of hyperinflammatory diseases. A number of factors limit translation into clinical use, including: potential contamination o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a21b4837d1c5c5331c36d007c724344
http://www.sciencedirect.com/science/article/pii/S2589909020300320
http://www.sciencedirect.com/science/article/pii/S2589909020300320
Autor:
Edward Mitre, Holly Evans, Rachel T. Cox, David Larson, C. Paul Morris, Marina N. Torrero, Yinghui Shi
Publikováno v:
Experimental Parasitology. 135:87-95
Antigens obtained from the intestinal tract of filarial nematodes have been proposed as potential safe and effective vaccine candidates. Because they may be ‘hidden’ from the immune response during natural infection, yet accessible by antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737e3b59872cabb7b9ad6074db5f6eb9
https://doi.org/10.1016/j.exppara.2013.05.018
https://doi.org/10.1016/j.exppara.2013.05.018
Autor:
Stephen Davies, Edward Mitre, Marc P. Hübner, David Larson, Amy Brankin, Marina N. Torrero, Becky M. Vonakis, Brett E. Swierczewski, Christopher P. Morris
Publikováno v:
The Journal of Immunology. 188:4188-4199
Basophils play a key role in the development and effector phases of type 2 immune responses in both allergic diseases and helminth infections. This study shows that basophils become less responsive to IgE-mediated stimulation when mice are chronicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e97aca968e6caa869b3ffbab34fce9
https://doi.org/10.4049/jimmunol.1101859
https://doi.org/10.4049/jimmunol.1101859
Autor:
Edward Mitre, David Larson, Marina N. Torrero, Kristin E. Killoran, Yinghui Shi, Ellen Mueller, Marc P. Hübner
Publikováno v:
Clinical Immunology. 141:205-217
Mounting evidence suggests that helminth infections protect against autoimmune diseases. As helminths cause chronic IgE-mediated activation of basophils and mast cells we hypothesized that continuous activation of these cells could prevent diabetes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::464bb855f420d7fda19dc962aae82a7c
https://doi.org/10.1016/j.clim.2011.08.004
https://doi.org/10.1016/j.clim.2011.08.004
Publikováno v:
The Journal of Immunology. 185:7426-7434
Chronic helminth infections induce a type 2 immune response characterized by eosinophilia, high levels of IgE, and increased T cell production of type 2 cytokines. Because basophils have been shown to be substantial contributors of IL-4 in helminth i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e7f177f7c4cad95b2a28f93bf60b27
https://doi.org/10.4049/jimmunol.0903864
https://doi.org/10.4049/jimmunol.0903864
Publikováno v:
The Journal of allergy and clinical immunology. 135(5)
Background Allergen-specific immunotherapy (ASIT) is used to treat the symptoms of immediate type I hypersensitivity. The mechanisms driving establishment of allergen tolerance are not yet fully understood. Objective The goal of this study was to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eadc0579db6ed83b37b23f87c3c855e
https://pubmed.ncbi.nlm.nih.gov/25282017
https://pubmed.ncbi.nlm.nih.gov/25282017
Basophils help establish protective immunity induced by irradiated larval vaccination for filariasis
Autor:
Marina N. Torrero, Edward Mitre, C. Paul Morris, Hajime Karasuyama, Ellen Mueller Fox, Blima K. Mitre, Marc P. Hübner
Basophils are increasingly recognized as playing important roles in the immune response toward helminths. In this study, we evaluated the role of basophils in vaccine-mediated protection against filariae, tissue-invasive parasitic nematodes responsib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c5fe89d24a28f0055d46f855444c5b
https://europepmc.org/articles/PMC3733094/
https://europepmc.org/articles/PMC3733094/
Autor:
Michael Rajnik, Christopher P. Morris, Marc P. Hübner, Edward Mitre, Kristin E. Killoran, Jorge C. G. Blanco, Val G. Hemming, Boris Nikonenko, Marina N. Torrero, Kevin C. Yim, Samuel R. Wilson
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1970 (2012)
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1970 (2012)
Background Chronic helminth infections induce a Th2 immune shift and establish an immunoregulatory milieu. As both of these responses can suppress Th1 immunity, which is necessary for control of Mycobacterium tuberculosis (MTB) infection, we hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90e17943674ea4b4353bfb0386e413a
http://europepmc.org/articles/PMC3529511
http://europepmc.org/articles/PMC3529511