Výsledky vyhledávání - "Marina Lomazzi"

Calcium and Calmodulin Are Essential for Ras-GRF1-Mediated Activation of the Ras Pathway by Lysophosphatidic Acid

Autor: Emmapaola Sturani, Renata Zippel, Monica Balestrini, Marina Lomazzi

Publikováno v: Experimental Cell Research. 258:403-408

The exchange factor Ras-GRF1, also called CDC25Mm, couples calcium signaling and G-protein-coupled receptors to Ras and downstream effectors. Here we show that when expressed in different cell lines Ras-GRF1 strongly enhances the level of active Ras

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2df5d79265b3f8d92aa5e809f8bbedb
https://doi.org/10.1006/excr.2000.4937

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Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry

Autor: Michael Rugaard Jensen, Emanuela Frittoli, Marina Lomazzi, M. Cristina Moroni, Kristian Helin

Publikováno v: Nature genetics. 31(2)

Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of cancer. In the absence of other genetic alterations, this deregulation results in lack of differentiation, hyperproliferation and apoptosis. The pRB protein acts as a transcrip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c1a841df7c68c0952715971b23d2c5
https://pubmed.ncbi.nlm.nih.gov/11992123

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