Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marina Kolbanovskiy"'
Autor:
Ana H. Sales, Marina Kolbanovskiy, Nicholas E. Geacintov, Kun-Ming Chen, Yuan-Wan Sun, Karam El-Bayoumy
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2110 (2022)
As demonstrated by us earlier and by other researchers, a diet containing freeze-dried black raspberries (BRB) inhibits DNA damage and carcinogenesis in animal models. We tested the hypothesis that the inhibition of DNA damage by BRB is due, in part,
Externí odkaz:
https://doaj.org/article/6affea84318e48c6a9ff316d2ca9194b
Autor:
Abraham Aharonoff, Nicholas E. Geacintov, Marina Kolbanovskiy, Ana Helena Sales, Vladimir Shafirovich
Publikováno v:
Biochemistry
The excision of DNA lesions by human Nucleotide Excision Repair (NER) has been extensively studied in human cell extracts. Employing DNA duplexes less than 200 base pairs (bp) in lengths containing single bulky, benzo[a]pyrene-derived guanine lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ccaa255ecf12fc31d2961e00721bd8d
https://doi.org/10.1021/acs.biochem.0c00441
https://doi.org/10.1021/acs.biochem.0c00441
Autor:
Nicholas E. Geacintov, Marina Kolbanovskiy, Vladimir Shafirovich, Abraham Aharonoff, Ana Helena Sales
Publikováno v:
Biochem J
The oxidatively generated genotoxic spiroiminodihydantoin (Sp) lesions are well-known substrates of the base excision repair (BER) pathway initiated by the bifunctional DNA glycosylase NEIL1. In this work, we reported that the excision kinetics of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e4f440f0294407e27ce48546a28a80
https://europepmc.org/articles/PMC8411440/
https://europepmc.org/articles/PMC8411440/
Autor:
Nicholas E. Geacintov, Suse Broyde, Shaofei Ji, Marina Kolbanovskiy, Natalia Y. Tretyakova, Maram M. Essawy, Konstantin Kropachev, Iwen Fu, Daeyoon Park
Publikováno v:
J Biol Chem
5-Formylcytosine (5fC) is an endogenous epigenetic DNA mark introduced via enzymatic oxidation of 5-methyl-dC in DNA. We and others recently reported that 5fC can form reversible DNA–protein conjugates with histone proteins, likely contributing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439e5ae2b0469a325e3a53e6650d4359
https://doi.org/10.1074/jbc.ra119.009834
https://doi.org/10.1074/jbc.ra119.009834
Autor:
Marina Kolbanovskiy, Abraham Aharonoff, Nicholas E. Geacintov, Vladimir Shafirovich, Ana Helena Sales
Publikováno v:
Chem Res Toxicol
The base and nucleotide excision repair (BER and NER, respectively) pathways are two major mechanisms that remove DNA lesions formed by the reactions of genotoxic intermediates with cellular DNA. We have demonstrated earlier that the oxidatively gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1264c2f87d6dc38eda63eb4bade4b7a1
https://europepmc.org/articles/PMC7883559/
https://europepmc.org/articles/PMC7883559/
Publikováno v:
Chemical research in toxicology. 32(4)
The interchange between different repair mechanisms in human cells has long been a subject of interest. Here, we provide a direct demonstration that the oxidatively generated guanine lesions spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh) em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3bfa59f031ccce8462c977a759e7d0
https://pubmed.ncbi.nlm.nih.gov/30688445
https://pubmed.ncbi.nlm.nih.gov/30688445
Autor:
Marina Kolbanovskiy, Alexander Dadali, Vladimir Shafirovich, Nicholas E. Geacintov, Konstantin Kropachev, Shantu Amin, Annalisa Masi, Chryssostomos Chatgilialoglu, Zhi Liu, Yuquin Cai, Michael A. Terzidis, Suse Broyde
Publikováno v:
Biochemistry (Easton) 58 (2019): 561–574. doi:10.1021/acs.biochem.8b01066
info:cnr-pdr/source/autori:Shafirovich, Vladimir; Kolbanovskiy, Marina; Kropachev, Konstantin; Liu, Zhi; Cai, Yuquin; Terzidis, Michael A.; Masi, Annalisa; Chatgilialoglu, Chryssostomos; Amin, Shantu; Dadali, Alexander; Broyde, Suse; Geacintov, Nicholas E./titolo:Nucleotide Excision Repair and Impact of Site-Specific 5 ',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes/doi:10.1021%2Facs.biochem.8b01066/rivista:Biochemistry (Easton)/anno:2019/pagina_da:561/pagina_a:574/intervallo_pagine:561–574/volume:58
info:cnr-pdr/source/autori:Shafirovich, Vladimir; Kolbanovskiy, Marina; Kropachev, Konstantin; Liu, Zhi; Cai, Yuquin; Terzidis, Michael A.; Masi, Annalisa; Chatgilialoglu, Chryssostomos; Amin, Shantu; Dadali, Alexander; Broyde, Suse; Geacintov, Nicholas E./titolo:Nucleotide Excision Repair and Impact of Site-Specific 5 ',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes/doi:10.1021%2Facs.biochem.8b01066/rivista:Biochemistry (Easton)/anno:2019/pagina_da:561/pagina_a:574/intervallo_pagine:561–574/volume:58
The non-bulky 5’,8-cyclopurine DNA lesions (cP) and the bulky, benzo[a]pyrene diol epoxide-derived stereoisomeric cis and trans-N(2)-guanine adducts (BPDE-dG) are good substrates of the human nucleotide excision repair (NER) mechanism. These DNA le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c3d7b0bc3beeb8b3eb3420c3161b6f
https://pubmed.ncbi.nlm.nih.gov/30570250
https://pubmed.ncbi.nlm.nih.gov/30570250
Autor:
Konstantin Kropachev, Yuqin Cai, Annalisa Masi, Nicholas E. Geacintov, Marina Kolbanovskiy, Vladimir Shafirovich, Shuang Ding, Zhi Liu, Chryssostomos Chatgilialoglu, Michael A. Terzidis, Suse Broyde
Publikováno v:
Nucleic Acids Research
Nucleic acids research 42 (2014): 5020–5032. doi:10.1093/nar/gku162
info:cnr-pdr/source/autori:Kropachev K.; Ding S.; Terzidis M.A.; Masi A.; Liu Z.; Cai Y.; Kolbanovskiy M.; Chatgilialoglu C.; Broyde S.; Geacintov N.E.; Shafirovich V./titolo:Structural basis for the recognition of diastereomeric 5',8-cyclo-2'-deoxypurine lesions by the human nucleotide excision repair system/doi:10.1093%2Fnar%2Fgku162/rivista:Nucleic acids research/anno:2014/pagina_da:5020/pagina_a:5032/intervallo_pagine:5020–5032/volume:42
Nucleic acids research 42 (2014): 5020–5032. doi:10.1093/nar/gku162
info:cnr-pdr/source/autori:Kropachev K.; Ding S.; Terzidis M.A.; Masi A.; Liu Z.; Cai Y.; Kolbanovskiy M.; Chatgilialoglu C.; Broyde S.; Geacintov N.E.; Shafirovich V./titolo:Structural basis for the recognition of diastereomeric 5',8-cyclo-2'-deoxypurine lesions by the human nucleotide excision repair system/doi:10.1093%2Fnar%2Fgku162/rivista:Nucleic acids research/anno:2014/pagina_da:5020/pagina_a:5032/intervallo_pagine:5020–5032/volume:42
The hydroxyl radical is a powerful oxidant that generates DNA lesions including the stereoisomeric R and S 5?,8-cyclo-2?-deoxyadenosine (cdA) and 5?,8-cyclo-2?-deoxyguanosine (cdG) pairs that have been detected in cellular DNA. Unlike some other oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7357b659ca644f8496a3d0386ea1a551
http://europepmc.org/articles/PMC4041128
http://europepmc.org/articles/PMC4041128
Autor:
Lu Zhang, Konstantin Kropachev, Nicholas E. Geacintov, Marina Kolbanovskiy, Shuang Ding, Yuqin Cai, Alexander Kolbanovskiy, Suse Broyde, Shantu Amin, Adam G. Schwaid, Zhi Liu
Publikováno v:
Chemical Research in Toxicology. 26:783-793
The structural origins of differences in susceptibilities of various DNA lesions to nucleotide excision repair (NER) are poorly understood. Here we compared, in the same sequence context, the relative NER dual incision efficiencies elicited by two st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5602541415d92555a7275e1aefe43dcf
https://doi.org/10.1021/tx400080k
https://doi.org/10.1021/tx400080k
Autor:
Nicholas E. Geacintov, Kent D. Sugden, Marina Kolbanovskiy, Brooke D. Martin, Jung Hyun Min, Zhi Liu, Konstantin Kropachev, Vladimir Shafirovich, Thomas Anderson, Yoonjung Shim, Xuejing Chen
The well known biomarker of oxidative stress, 8-oxo-7,8-dihydroguanine, is more susceptible to further oxidation than the parent guanine base and can be oxidatively transformed to the genotoxic spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2583bbaeeb9fccfc6ca2f2f994263
https://europepmc.org/articles/PMC4777862/
https://europepmc.org/articles/PMC4777862/