Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marina Kirkitadze"'
Autor:
Jessica Duprez, Kristen Kalbfleisch, Sasmit Deshmukh, Jessie Payne, Manjit Haer, Wayne Williams, Ibrahim Durowoju, Marina Kirkitadze
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 439-447 (2021)
Purpose: The goal of this study was to characterize an acellular pertussis vaccine (Tdap) containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH adjuvant. Methods: Several analytical tools including nanoDSF, FTIR, an
Externí odkaz:
https://doaj.org/article/66d02d0a692647a7818df298c6e5436d
Autor:
Jessie Payne, James Cronin, Manjit Haer, Jason Krouse, William Prosperi, Katherine Drolet-Vives, Matthew Lieve, Michael Soika, Matthew Balmer, Marina Kirkitadze
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1829-1837 (2021)
Purpose: The goal of this study is to examine the suitability of in-line infrared measurements to monitor, in real-time, surfactant concentration in the viral vaccine drug substance during a 50KDa tangential flow filtration (TFF) process. Methods: A
Externí odkaz:
https://doaj.org/article/bbb27a524ee64b8e91d402490b4aad81
Autor:
Kristen Kalbfleisch, Sasmit Deshmukh, Carmen Mei, Moriam Ore, Wayne Williams, Ibrahim Durowoju, Jessica Duprez, Sylvie Morin, Bruce Carpick, Marina Kirkitadze
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 14-20 (2019)
Purpose: The goal of this study is to set an empirical baseline to map the structure-function relation of the antigens from the commercialized vaccine products. Methods: To study the structural changes of protein antigens after adsorption several ana
Externí odkaz:
https://doaj.org/article/59cb11c9209845ce934473361a9087cc
Autor:
Carmen Mei, Sasmit Deshmukh, James Cronin, Shuxin Cong, Daniel Chapman, Nicole Lazaris, Liliana Sampaleanu, Ulrich Schacht, Katherine Drolet-Vives, Moriam Ore, Sylvie Morin, Bruce Carpick, Matthew Balmer, Marina Kirkitadze
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1184-1194 (2019)
Purpose: Aluminum-based adjuvants including aluminum phosphate (AlPO4) are commonly used in many human vaccines to enhance immune response. The interaction between the antigen and adjuvant, including the physical adsorption of antigen, may play a rol
Externí odkaz:
https://doaj.org/article/027dd679e94c405880b32f10cfecb4ac
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 15, Iss , Pp 14-20 (2017)
This study describes the NMR-based method to determine the limit of quantitation (LOQ) and limit of detection (LOD) of cholesterol, a process-related impurity in the replication-deficient Herpes Simplex Virus (HSV) type 2 candidate vaccine HSV529. Th
Externí odkaz:
https://doaj.org/article/757898d02ea544e994b1949ecf3712a1
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 154-160 (2016)
Bacille Calmette–Guerin, BCG, is a live attenuated bovine tubercle bacillus used for the treatment of non-muscle invasive bladder cancer. In this study, an Electrical Sensing Zone (ESZ) method was developed to measure the particle count and the siz
Externí odkaz:
https://doaj.org/article/b0f5a06327d5468ab762b76acadc07c9
Autor:
Marc B. Taraban, Teresia Ndung’u, Pratima Karki, Kira Li, Ginny Fung, Marina Kirkitadze, Y. Bruce Yu
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75d56d5ac6e1f47313d0ad51d3d32fbe
https://doi.org/10.1007/s11095-023-03528-7
https://doi.org/10.1007/s11095-023-03528-7
Autor:
Sasmit S. Deshmukh, Wayne Williams, Jessie Rose Payne, Manjit Haer, Kristen Kalbfleisch, Ibrahim Durowoju, Marina Kirkitadze, Jessica Duprez
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 439-447 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Purpose The goal of this study was to characterize an acellular pertussis vaccine (Tdap) containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH adjuvant. Methods Several analytical tools inclu
Purpose The goal of this study was to characterize an acellular pertussis vaccine (Tdap) containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH adjuvant. Methods Several analytical tools inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735e6521a035760843cac5af0c24fbbe
http://www.sciencedirect.com/science/article/pii/S2001037020305481
http://www.sciencedirect.com/science/article/pii/S2001037020305481
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 207
Process Analytical Technology (PAT) instruments include analyzers capable of measuring physical and chemical process parameters and key attributes with the goal of optimizing process controls. PAT in the form of a probe or sensor is designed to integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bad64b6adb7c1ee8696aced1c3c2ac
https://pubmed.ncbi.nlm.nih.gov/34607168
https://pubmed.ncbi.nlm.nih.gov/34607168
Autor:
Ulrich Schacht, Carmen Mei, Liliana M. Sampaleanu, Nicole Lazaris, Marina Kirkitadze, Shuxin Cong, James Cronin, Matthew Balmer, Sylvie Morin, Daniel Chapman, Sasmit S. Deshmukh, Katherine Drolet-Vives, Moriam O. Ore, Bruce Carpick
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1184-1194 (2019)
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1184-1194 (2019)
Purpose Aluminum-based adjuvants including aluminum phosphate (AlPO4) are commonly used in many human vaccines to enhance immune response. The interaction between the antigen and adjuvant, including the physical adsorption of antigen, may play a role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a91b17231a1a8e219974b19a3d4b8a
https://doi.org/10.1016/j.csbj.2019.08.003
https://doi.org/10.1016/j.csbj.2019.08.003