Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Marina Harvie"'
Publikováno v:
International Journal of Infectious Diseases, Vol 66, Iss C, Pp 26-32 (2018)
Objective: The aim of this study was to develop a vaccine against schistosomiasis, which is a major challenge due to the complex lifecycle of the causative schistosome parasite. Methods: SmKI-1 is a 16-kDa Kunitz-type protease inhibitor present in th
Externí odkaz:
https://doaj.org/article/9ecf20d34d4f444b8fef9d01f2d36cec
Autor:
Gail M. Williams, Yue-Sheng Li, Darren J. Gray, Zheng-Yuan Zhao, Donald A. Harn, Lisa M. Shollenberger, Sheng-Ming Li, Xinglin Yu, Zeng Feng, Jia-Gang Guo, Jie Zhou, Yu-Lan Dong, Yuan Li, Biao Guo, Patrick Driguez, Marina Harvie, Hong You, Allen G. Ross, Donald P. McManus
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Despite significant progress, China faces the challenge of re-emerging schistosomiasis transmission in currently controlled areas due, in part, to the presence of a range of animal reservoirs, notably water buffalo and cattle, which can harbor Schist
Externí odkaz:
https://doaj.org/article/885a26bae6b44aaa83f13cdd773bbd46
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003760 (2015)
BACKGROUND:We report the use of an ex vivo precision cut liver slice (PCLS) mouse model for studying hepatic schistosomiasis. In this system, liver tissue is unfixed, unfrozen, and alive for maintenance in culture and subsequent molecular analysis. M
Externí odkaz:
https://doaj.org/article/74dc4f1ecaef408486e2f2675cde8090
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 99, Pp 33-36 (2004)
The incidences of schistosomiasis and multiple sclerosis (MS) are mutually exclusive worldwide suggesting that schistosomiasis may offer protection against the induction of the immune-mediated disease, MS. Recent studies using the mouse model of MS,
Externí odkaz:
https://doaj.org/article/8548ed6786384598bcb8964c7411e511
Autor:
Connor P. O'Meara, Jesse Peet, Marina Harvie, Charles W. Armitage, Kenneth W. Beagley, Peter Timms, Zachary N. Phillips, Alison J. Carey
Publikováno v:
Immunology & Cell Biology. 97:865-876
Chlamydia infection remains the leading sexually-transmitted bacterial infection worldwide, causing damaging sequelae such as tubal scarring, infertility and ectopic pregnancy. As infection is often asymptomatic, prevention via vaccination is the opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4479bad19aea17c5db000821b223008e
https://doi.org/10.1111/imcb.12285
https://doi.org/10.1111/imcb.12285
Autor:
Lisa M. Shollenberger, Jia-Gang Guo, Sheng-Ming Li, Donald A. Harn, Hong You, Patrick Driguez, Donald P. McManus, Yu-Lan Dong, Zeng Feng, Zheng-Yuan Zhao, Gail M. Williams, Allen G. Ross, Yuan Li, Biao Guo, Jie Zhou, Marina Harvie, Xinglin Yu, Yuesheng Li, Darren J. Gray
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Despite significant progress, China faces the challenge of re-emerging schistosomiasis transmission in currently controlled areas due, in part, to the presence of a range of animal reservoirs, notably water buffalo and cattle, which can harbor Schist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112c77fc128234bac1fa7d9c8647bf64
http://europepmc.org/articles/PMC6456715
http://europepmc.org/articles/PMC6456715
Publikováno v:
Experimental parasitology. 204
Characterisation of the cellular immune response to schistosomiasis is well established for Schistosoma mansoni but a comprehensive description of T cell-mediated immune responses against S. japonicum infection is lacking. Accordingly, 20 CBA mice we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82f94b41e5d72867665febc8d8efa9e
https://pubmed.ncbi.nlm.nih.gov/31306646
https://pubmed.ncbi.nlm.nih.gov/31306646
Autor:
Malcolm K. Jones, Carolina De Marco Verissimo, Kieran V. Aland, Donald P. McManus, Helen Owen, Simon Reid, Rebecca J. Traub, Mahdis Aghazadeh, James S. McCarthy, Marina Harvie
Publikováno v:
Parasitology. 143:1243-1251
SUMMARYThis study investigated comparatively the pathogenicity of experimental infection of mice and guinea pigs, with Angiostrongylus mackerrasae and the closely related species A. cantonensis. Time course analyses showed that A. mackerrasae causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c06403ddc13641286948270fd4eb818
https://doi.org/10.1017/s003118201600069x
https://doi.org/10.1017/s003118201600069x
Publikováno v:
International Journal of Molecular Sciences
There is a pressing need to develop vaccines for schistosomiasis given the current heavy dependency on praziquantel as the only available drug for treatment. We previously showed the ligand domain of the Schistosoma japonicum insulin receptor 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c355b42bd3c060f97bcb03e193a59b2
https://pubmed.ncbi.nlm.nih.gov/30304851
https://pubmed.ncbi.nlm.nih.gov/30304851
Autor:
Hong, You, Chang, Liu, Xiaofeng, Du, Sujeevi, Nawaratna, Vanessa, Rivera, Marina, Harvie, Malcolm, Jones, Donald P, McManus
Publikováno v:
International Journal of Molecular Sciences
To further investigate the importance of Schistosoma japonicum acetylcholinesterase (SjAChE) in cholinergic signaling for parasite growth and development, we used RNA interference (RNAi) to knock-down its expression in adults and eggs in vitro. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1aa44288b2322cbce7d0123905c282a
https://pubmed.ncbi.nlm.nih.gov/30115897
https://pubmed.ncbi.nlm.nih.gov/30115897