Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Marina Guizzetti"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The role astrocytes play in brain development and function has garnered greater attention as the diversity of roles they are involved in has become apparent. We have previously shown that ethanol-exposed astrocytes alter neuronal neurite outgrowth in
Externí odkaz:
https://doaj.org/article/364cd692c40446228c5bf0be4291cde9
Autor:
Harish R. Krishnan, Gian Paolo Vallerini, Hannah E. Gavin, Marina Guizzetti, Hooriyah S. Rizavi, David P. Gavin, Rajiv P. Sharma
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
We report on the effects of ethanol (EtOH) and Poly (ADP-ribose) polymerase (PARP) inhibition on RNA ribosomal engagement, as a proxy for protein translation, in prefrontal cortical (PFC) pyramidal neurons. We hypothesized that EtOH induces a shift i
Externí odkaz:
https://doaj.org/article/e8c583c98e94474d810827584b3aeb76
Autor:
Ji-in Vivien Choi, Boriana K. Tchernookova, Wasan Kumar, Lech Kiedrowski, Calla Goeke, Marina Guizzetti, John Larson, Matthew A. Kreitzer, Robert Paul Malchow
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Small alterations in the level of extracellular H+ can profoundly alter neuronal activity throughout the nervous system. In this study, self-referencing H+-selective microelectrodes were used to examine extracellular H+ fluxes from individual astrocy
Externí odkaz:
https://doaj.org/article/4ed3395c6d284d03aa319593dc6ad6f2
Autor:
Carolyn E. Jones, Alex Q. Chau, Randall J. Olson, Cynthia Moore, Peyton T. Wickham, Niyati Puranik, Marina Guizzetti, Hung Cao, Charles K. Meshul, Miranda M. Lim
Publikováno v:
Current Research in Neurobiology, Vol 2, Iss , Pp 100020- (2021)
Early life experiences are crucial for proper organization of excitatory synapses within the brain, with outsized effects on late-maturing, experience-dependent regions such as the medial prefrontal cortex (mPFC). Previous work in our lab showed that
Externí odkaz:
https://doaj.org/article/efc17e643054440a936494df147d6f2e
Autor:
Dar’ya Y. Pozhidayeva, Sean P. Farris, Calla M. Goeke, Evan J. Firsick, Kayla G. Townsley, Marina Guizzetti, Angela R. Ozburn
Publikováno v:
Brain Sciences, Vol 10, Iss 2, p 109 (2020)
Binge drinking is a dangerous pattern of behavior. We tested whether chronically manipulating nucleus accumbens (NAc) activity (via clozapine-N-oxide (CNO) and Designer Receptors Exclusively Activated by Designer Drugs (DREADD)) could produce lasting
Externí odkaz:
https://doaj.org/article/f5d32ff5414c491eb46eb5350c88ef9f
Autor:
Deborah A. Finn, Joel G. Hashimoto, Debra K. Cozzoli, Melinda L. Helms, Michelle A. Nipper, Moriah N. Kaufman, Kristine M. Wiren, Marina Guizzetti
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
We previously determined that repeated binge ethanol drinking produced sex differences in the regulation of signaling downstream of Group 1 metabotropic glutamate receptors in the nucleus accumbens (NAc) of adult C57BL/6J mice. The purpose of the pre
Externí odkaz:
https://doaj.org/article/5d059925f3734e9a90a9cb3d464a9749
Autor:
David P. Gavin, Joel G. Hashimoto, Nathan H. Lazar, Lucia Carbone, John C. Crabbe, Marina Guizzetti
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Alcohol use disorder (AUD) is a chronic mental illness in which patients often achieve protracted periods of abstinence prior to relapse. Epigenetic mechanisms may provide an explanation for the persisting gene expression changes that can be observed
Externí odkaz:
https://doaj.org/article/f27f20705f744d7ab502164996bd65e9
Autor:
Joel G. Hashimoto, Mo L. Singer, Calla M. Goeke, Fuming Zhang, Yuefan Song, Ke Xia, Robert J. Linhardt, Marina Guizzetti
Publikováno v:
Experimental neurology.
In this study we investigated the effects of a neonatal handling protocol that mimics the handling of sham control pups in protocols of neonatal exposure to brain insults on dendritic arborization and glycosaminoglycan (GAG) levels in the developing
Autor:
Heather C. Aziz, Joel G. Hashimoto, Amanda Roberts, Marisa Roberto, Marina Guizzetti, Regina A. Mangieri
Publikováno v:
Alcohol. 109:93
Autor:
Miranda M. Lim, Niyati Puranik, Cynthia Moore, Alex Q. Chau, Marina Guizzetti, Randall Olson, Carolyn E. Jones, Hung Cao, Charles K. Meshul, Peyton Teutsch Wickham
Publikováno v:
Current Research in Neurobiology, Vol 2, Iss, Pp 100020-(2021)
Early life experiences are crucial for proper organization of excitatory synapses within the brain, with outsized effects on late-maturing, experience-dependent regions such as the medial prefrontal cortex (mPFC). Previous work in our lab showed that