Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marina Galchenkova"'
Autor:
Andreas Prester, Markus Perbandt, Marina Galchenkova, Dominik Oberthuer, Nadine Werner, Alessandra Henkel, Julia Maracke, Oleksandr Yefanov, Johanna Hakanpää, Guillaume Pompidor, Jan Meyer, Henry Chapman, Martin Aepfelbacher, Winfried Hinrichs, Holger Rohde, Christian Betzel
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The emergence and spread of antibiotic resistance represent a growing threat to public health. Of particular concern is the appearance of β-lactamases, which are capable to hydrolyze and inactivate the most important class of antibiotics, t
Externí odkaz:
https://doaj.org/article/8df6755d143d4e47afcdc923e679304e
Autor:
Patrick Y. A. Reinke, Robin Schubert, Dominik Oberthür, Marina Galchenkova, Aida Rahmani Mashhour, Sebastian Günther, Anaïs Chretien, Adam Round, Brandon Charles Seychell, Brenna Norton-Baker, Chan Kim, Christina Schmidt, Faisal H. M. Koua, Alexandra Tolstikova, Wiebke Ewert, Gisel Esperanza Peña Murillo, Grant Mills, Henry Kirkwood, Hévila Brognaro, Huijong Han, Jayanath Koliyadu, Joachim Schulz, Johan Bielecki, Julia Lieske, Julia Maracke, Juraj Knoska, Kristina Lorenzen, Lea Brings, Marcin Sikorski, Marco Kloos, Mohammad Vakili, Patrik Vagovic, Philipp Middendorf, Raphael de Wijn, Richard Bean, Romain Letrun, Seonghyun Han, Sven Falke, Tian Geng, Tokushi Sato, Vasundara Srinivasan, Yoonhee Kim, Oleksandr M. Yefanov, Luca Gelisio, Tobias Beck, Andrew S. Doré, Adrian P. Mancuso, Christian Betzel, Saša Bajt, Lars Redecke, Henry N. Chapman, Alke Meents, Dušan Turk, Winfried Hinrichs, Thomas J. Lane
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The main protease (Mpro) of SARS-CoV-2 is critical for viral function and a key drug target. Mpro is only active when reduced; turnover ceases upon oxidation but is restored by re-reduction. This suggests the system has evolved to survive pe
Externí odkaz:
https://doaj.org/article/7a737b71ae764265a7f11a3df650ea0b
Autor:
Marina Galchenkova, Alexandra Tolstikova, Bjarne Klopprogge, Janina Sprenger, Dominik Oberthuer, Wolfgang Brehm, Thomas A. White, Anton Barty, Henry N. Chapman, Oleksandr Yefanov
Publikováno v:
IUCrJ, Vol 11, Iss 2, Pp 190-201 (2024)
Serial crystallography (SX) has become an established technique for protein structure determination, especially when dealing with small or radiation-sensitive crystals and investigating fast or irreversible protein dynamics. The advent of newly devel
Externí odkaz:
https://doaj.org/article/7172b08f189341d2b6450e8be4c657b5
Autor:
Alessandra Henkel, Marina Galchenkova, Julia Maracke, Oleksandr Yefanov, Bjarne Klopprogge, Johanna Hakanpää, Jeroen R. Mesters, Henry N. Chapman, Dominik Oberthuer
Publikováno v:
IUCrJ, Vol 10, Iss 3, Pp 253-260 (2023)
Macromolecular crystallography is a well established method in the field of structural biology and has led to the majority of known protein structures to date. After focusing on static structures, the method is now under development towards the inves
Externí odkaz:
https://doaj.org/article/362557cc99dc439c826696ac2d78e16b
Autor:
Yaroslav Gevorkov, Marina Galchenkova, Valerio Mariani, Anton Barty, Thomas A. White, Henry N. Chapman, Oleksandr Yefanov
Publikováno v:
Crystals, Vol 14, Iss 2, p 164 (2024)
Serial crystallography (SX) is a cutting-edge technique in structural biology, involving the systematic collection of X-ray diffraction data from numerous randomly oriented microcrystals. To extract comprehensive three-dimensional information about t
Externí odkaz:
https://doaj.org/article/454c66b102d04065b6b252a7f1bd06fa
Autor:
Vasundara Srinivasan, Hévila Brognaro, Prince R. Prabhu, Edmarcia Elisa de Souza, Sebastian Günther, Patrick Y. A. Reinke, Thomas J. Lane, Helen Ginn, Huijong Han, Wiebke Ewert, Janina Sprenger, Faisal H. M. Koua, Sven Falke, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Bruno Alves Franca, Mengying Wang, Angélica Luana C. Barra, Markus Perbandt, Martin Schwinzer, Christina Schmidt, Lea Brings, Kristina Lorenzen, Robin Schubert, Rafael Rahal Guaragna Machado, Erika Donizette Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Stephan Niebling, Angelica Struve Garcia, Oleksandr Yefanov, Julia Lieske, Luca Gelisio, Martin Domaracky, Philipp Middendorf, Michael Groessler, Fabian Trost, Marina Galchenkova, Aida Rahmani Mashhour, Sofiane Saouane, Johanna Hakanpää, Markus Wolf, Maria Garcia Alai, Dusan Turk, Arwen R. Pearson, Henry N. Chapman, Winfried Hinrichs, Carsten Wrenger, Alke Meents, Christian Betzel
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Three natural phenolic compounds are found to bind to an allosteric site in SARS-CoV-2 papain-like protease and exhibit antiviral activity in vitro, showing potential as starting scaffolds for drug design.
Externí odkaz:
https://doaj.org/article/94a6b8437953446b80663a578e6c235a
Autor:
Marina Galchenkova, Aida Rahmani Mashhour, Patrick Y. A. Reinke, Sebastian Günther, Jan Meyer, Henry N. Chapman, Oleksandr M. Yefanov
Publikováno v:
Crystals, Vol 13, Iss 8, p 1225 (2023)
Serial crystallography is a rapidly developing method for the determination of the structure of biomolecules at room temperature at near-atomic resolution from an ensemble of small crystals. Numerous advances in detectors, data analysis pipelines, sa
Externí odkaz:
https://doaj.org/article/2b30a77376ea4aebb957d461e536d4df
Autor:
Alessandra Henkel, Marina Galchenkova, Julia Maracke, Oleksandr Yefanov, Bjarne Klopprogge, Johanna Hakanpää, Jeroen R. Mesters, Henry N. Chapman, Dominik Oberthuer
Publikováno v:
IUCrJ 10(3), 253-260 (2023). doi:10.1107/S2052252523001653
IUCrJ 10(3), 253 - 260 (2023). doi:10.1107/S2052252523001653
Macromolecular crystallography is a well-established method in the field of structure biology and has led to the majority of known protein structures to date. After focusing on static
Macromolecular crystallography is a well-established method in the field of structure biology and has led to the majority of known protein structures to date. After focusing on static
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a4bfbf1d212827757854a9b3611901
https://doi.org/10.1101/2022.10.26.513656
https://doi.org/10.1101/2022.10.26.513656
Autor:
Alireza Sadri, Marjan Hadian-Jazi, Oleksandr Yefanov, Marina Galchenkova, Henry Kirkwood, Grant Mills, Marcin Sikorski, Romain Letrun, Raphael de Wijn, Mohammad Vakili, Dominik Oberthuer, Dana Komadina, Wolfgang Brehm, Adrian P. Mancuso, Jerome Carnis, Luca Gelisio, Henry N. Chapman
Publikováno v:
Journal of applied crystallography 55, 1549-1561 (2022). doi:10.1107/S1600576722009815
Journal of applied crystallography 55, 1549 - 1561 (2022). doi:10.1107/S1600576722009815
X-ray crystallography has witnessed a massive development over the past decade, driven by large increases in the intensity and brightness of X-ray sources a
X-ray crystallography has witnessed a massive development over the past decade, driven by large increases in the intensity and brightness of X-ray sources a
Autor:
Lainey J. Williamson, Marina Galchenkova, Hannah L. Best, Richard J. Bean, Anna Munke, Salah Awel, Gisel Pena, Juraj Knoska, Robin Schubert, Katerina Doerner, Hyun-Woo Park, Dennis K. Bideshi, Alessandra Henkel, Viviane Kremling, Bjarne Klopprogge, Emyr Lloyd-Evans, Mark Young, Joana Valerio, Marco Kloos, Marcin Sikorski, Grant Mills, Johan Bielecki, Henry Kirkwood, Chan Kim, Raphael de Wijn, Kristina Lorenzen, P. Lourdu Xavier, Aida Rahmani, Luca Gelisio, Oleksandr Yefanov, Adrian P. Mancuso, Brian Federici, Henry N. Chapman, Neil Crickmore, Pierre J. Rizkallah, Colin Berry, Dominik Oberthür
Tpp49Aa1 fromLysinibacillus sphaericusis a Toxin_10 family protein that – in combination with Cry48Aa1, a 3-domain crystal protein - has potent mosquitocidal activity, specifically againstCulex quinquefasciatusmosquitoes. MHz serial femtosecond cry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46fb447bc0ed67262e42b24808246b41
https://doi.org/10.1101/2022.01.14.476343
https://doi.org/10.1101/2022.01.14.476343