Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Marina De Paula Silva"'
Autor:
Silvana Sandri, Cristina Bichels Hebeda, Milena Fronza Broering, Marina de Paula Silva, Luciana Facure Moredo, Milton José de Barros e Silva, André Sapata Molina, Clóvis Antônio Lopes Pinto, João Pedreira Duprat Neto, Chris P. Reutelingsperger, Cristiane Damas Gil, Sandra Helena Poliselli Farsky
Publikováno v:
Cells, Vol 12, Iss 3, p 425 (2023)
Annexin A1 (AnxA1) is highly secreted by neutrophils and binds to formyl peptide receptors (FPRs) to trigger anti-inflammatory effects and efferocytosis. AnxA1 is also expressed in the tumor microenvironment, being mainly attributed to cancer cells.
Externí odkaz:
https://doaj.org/article/8c0fc4ca602d42638af809e85a9cfa23
Autor:
Cristina Bichels Hebeda, Anna Carolina Savioli, Pablo Scharf, Marina de Paula-Silva, Cristiane Damas Gil, Sandra Helena Poliselli Farsky, Silvana Sandri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Maternal neutrophils cells are players in gestational tolerance and fetus delivery. Nonetheless, their actions in each phase of the pregnancy are unknown. We here investigated the role of maternal neutrophil depletion before the blastocyst implantati
Externí odkaz:
https://doaj.org/article/661d09eaa11f45ca905c2675da0dd902
Autor:
Marina de Paula-Silva, Gustavo Henrique Oliveira da Rocha, Milena Fronza Broering, Maria Luíza Queiroz, Silvana Sandri, Rodrigo Azevedo Loiola, Sonia Maria Oliani, Andrea Vieira, Mauro Perretti, Sandra Helena Poliselli Farsky
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Non-responsiveness to anti-TNF-α therapies presents relevant rates in inflammatory bowel disease patients, presenting the need to find biomarkers involved in therapeutic efficacy. Herein, we demonstrate that higher levels of colonic formyl peptide r
Externí odkaz:
https://doaj.org/article/c70005d39fa940c9a3d21cd717ae0035
Autor:
Gustavo Henrique Oliveira da Rocha, Marina de Paula-Silva, Milena Fronza Broering, Pablo Rhasan dos Santos Scharf, Larissa Satiko Alcântara Sekimoto Matsuyama, Silvya Stuchi Maria-Engler, Sandra Helena Poliselli Farsky
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Ulcerative colitis and Crohn’s disease are chronic inflammatory bowel diseases (IBDs) which burden health systems worldwide; available pharmacological therapies are limited and cost-intensive. Use of peroxisome proliferator activated-receptor γ (P
Externí odkaz:
https://doaj.org/article/b0b7383894b545aa80a7b09c26faf4b2
Autor:
Alessandra Vidotto, Giovana M. Polachini, Marina de Paula-Silva, Sonia M. Oliani, Tiago Henrique, Rossana V. M. López, Patrícia M. Cury, Fabio D. Nunes, José F. Góis-Filho, Marcos B. de Carvalho, Andréia M. Leopoldino, Eloiza H. Tajara
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-16 (2018)
Abstract Background Lymph node metastasis is one of the most important prognostic factors in head and neck squamous cell carcinomas (HNSCCs) and critical for delineating their treatment. However, clinical and histological criteria for the diagnosis o
Externí odkaz:
https://doaj.org/article/f824340606ce44dd9b6d107a0a40ed79
Autor:
Cristina B. Hebeda, Silvana Sandri, Cláudia M. Benis, Marina de Paula-Silva, Rodrigo A. Loiola, Chris Reutelingsperger, Mauro Perretti, Sandra H. P. Farsky
Publikováno v:
Cells, Vol 9, Iss 5, p 1188 (2020)
Embryo implantation into the uterine wall is a highly modulated, complex process. We previously demonstrated that Annexin A1 (AnxA1), which is a protein secreted by epithelial and inflammatory cells in the uterine microenvironment, controls embryo im
Externí odkaz:
https://doaj.org/article/7aaf098a691d4cf4bb407e22d197d61d
Autor:
Gustavo Henrique Oliveira da Rocha, Rodrigo Azevedo Loiola, Marina de Paula-Silva, Fumitaka Shimizu, Takashi Kanda, Andrea Vieira, Fabien Gosselet, Sandra Helena Poliselli Farsky
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12781
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biological mediators secreted during peripheral chronic inflammation reach the bloodstream and may damage the blood–brain barrier (BBB), triggering central nervous system (CNS) disorders. Full-fledged human BBB models are efficient tools to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce96ff43ce21def1e3231f33655aeb61
Autor:
Chris P. M. Reutelingsperger, Jianmin Chen, Dianne Cooper, Mauro Perretti, Jose Garrido Mesa, Lucy V. Norling, Marina De Paula Silva, Sophie E. Burton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118(38):e2020385118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Patients with rheumatoid arthritis (RA) are susceptible to heart failure accompanied by diastolic dysfunction. It is unknown what causes diastolic dysfunction in RA, and current therapies do not reduce the risk of heart problems. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa88bd0f0fb57ebd84d7588ecd61f2d
https://doi.org/10.1073/pnas.2020385118
https://doi.org/10.1073/pnas.2020385118
Autor:
Bruna Stuqui, Marina de Paula-Silva, Carla Patrícia Carlos, Anwar Ullah, Raghuvir Krishnaswamy Arni, Cristiane Damas Gil, Sonia Maria Oliani
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0130803 (2015)
Annexin A1 (AnxA1) is an endogenous glucocorticoid regulated protein that modulates anti-inflammatory process and its therapeutic potential has recently been recognized in a range of systemic inflammatory disorders. The effect of the N-terminal pepti
Externí odkaz:
https://doaj.org/article/c30097791b654de79b446dfd946bd1a0
Autor:
Sérgio Hiroshi Toma, Koiti Araki, Roberta Cardoso, Mariana Romano, Cristina Bichels Hebeda, Silvana Sandri, Sandra Helena Poliselli Farsky, Mayara Klimuk Uchiyama, Marina de Paula-Silva
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Aim: The low solubility and consequent poor bioavailability of ibuprofen (IBU) is a major drawback that can be overcome by anchoring IBU on ultrasmall superparamagnetic iron oxide nanoparticles (USPIONs) as effective multifunctional carriers for drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f797ba5489d49f1f360a98205a89695
