Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Marina Danalache"'
Autor:
Julius Michael Wolfgart, Lea Cathrine Grötzner, Sascha Hemayatkar-Fink, Maik Schwitalle, Florian Christof Bonnaire, Martina Feierabend, Marina Danalache, Ulf Krister Hofmann
Publikováno v:
Journal of Orthopaedic Translation, Vol 48, Iss , Pp 232-243 (2024)
Background: In healthy articular cartilage, chondrocytes are found along arcades of collagen fibers as Single Strings. With onset of cartilage degeneration this pattern changes to Double Strings. In the course of osteoarthritis Small Clusters, and fi
Externí odkaz:
https://doaj.org/article/fb59ad23a07d4a80923f034b82799129
Autor:
Cyril Daniel, Frank Traub, Saskia Sachsenmaier, Rosa Riester, Moritz Mederake, Christian Konrads, Marina Danalache
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Cancer cells are characterized by changes in cell cytoskeletal architecture and stiffness. Despite advances in understanding the molecular mechanisms of musculoskeletal cancers, the corresponding cellular mechanical properties rem
Externí odkaz:
https://doaj.org/article/3a5291cebb2f440fa4c1a7569ca8ab98
Autor:
Anna Cykowska, Ulf Krister Hofmann, Aadhya Tiwari, Corinna Kosnopfel, Rosa Riester, Marina Danalache
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Malignant melanoma is the most lethal form of skin cancer. Y-box binding protein 1 (YB-1) plays a prominent role in mediating metastatic behavior by promoting epithelial-to-mesenchymal transition (EMT). Migratory melanoma cells exhibit two major migr
Externí odkaz:
https://doaj.org/article/ac787a203b6d446f89542f4083e40a4e
Autor:
Sebastian Höflsauer, Florian Christof Bonnaire, Charlotte Emma Bamberger, Marina Danalache, Martina Feierabend, Ulf Krister Hofmann
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Analogous to articular cartilage, changes in spatial chondrocyte organisation have been proposed to be a strong indicator for local tissue degeneration in the intervertebral disc (IVD). While a progressive structural and functional degradation of the
Externí odkaz:
https://doaj.org/article/068d8f0f4019495295f3f6cabdeab68e
Autor:
Felix Umrath, Achim Pfeifer, Wanjing Cen, Marina Danalache, Siegmar Reinert, Dorothea Alexander, Andreas Naros
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Dexamethasone (dexa) is commonly used to stimulate osteogenic differentiation of mesenchymal stem/stromal cells (MSCs) in vitro. However, it is paradoxical that glucocorticoids (GCs) such as dexa lead to bone loss and increased fracture risk in patie
Externí odkaz:
https://doaj.org/article/897076e259be43989ed37719e9b4ed84
Autor:
Marina Danalache, Kevin Ralf Beutler, Bernd Rolauffs, Julius Michael Wolfgart, Florian Christof Bonnaire, Stefan Fischer, Imke Greving, Ulf Krister Hofmann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Using two-dimensional top-down view microscopy, researchers have recently described chondrocytes as being spatially arranged in distinct patterns such as strings, double strings, and small and large clusters. Because of the seeming associati
Externí odkaz:
https://doaj.org/article/1639485ef297488cbcc2c013107d0660
Autor:
Lea Marocco, Felix Umrath, Saskia Sachsenmaier, Robert Rabiner, Nikolaus Wülker, Marina Danalache
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2900 (2022)
Ewing sarcomas (ES) are aggressive primary bone tumors that require radical therapy. Promising low toxicity, 5-aminolevulinic acid (5-ALA)-mediated photodynamic therapy (PDT) could enhance the effectiveness of conventional treatment modalities (e.g.,
Externí odkaz:
https://doaj.org/article/99c4a4d5a4794c8e8b9e927ba3b990a0
Autor:
Saskia Magdalen Sachsenmaier, Frank Traub, Anna Cykowska, Rosa Riester, Nikolaus Wülker, Christian Walter, Marina Danalache
Publikováno v:
Biology, Vol 10, Iss 10, p 1020 (2021)
Bone is a frequent site of metastases, being typically associated with a short-term prognosis in affected patients. Photodynamic therapy (PDT) emerges as a promising alternative treatment for controlling malignant disease that can directly target int
Externí odkaz:
https://doaj.org/article/544a9097e79a4db8a899a7ec0fe1122e
Akademický článek
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Publikováno v:
Journal of Visualized Experiments.
Without a doubt, atomic force microscopy (AFM) is currently one of the most powerful and useful techniques to assess micro and even nano-cues in the biological field. However, as with any other microscopic approach, methodological challenges can aris