Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Marina Concli Leite"'
Autor:
Jéssica Taday, Fernanda Telles Fróes, Marina Seady, Carlos Alberto Gonçalves, Marina Concli Leite
Publikováno v:
Metabolites, Vol 14, Iss 3, p 151 (2024)
Astrocytes play fundamental roles in the maintenance of brain homeostasis. The dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers GFAP and S100B, in addit
Externí odkaz:
https://doaj.org/article/74c4f9a7c51f4857b23599194b101956
Autor:
Adriana Fernanda K. Vizuete, Fernanda Hansen, Elisa Negri, Marina Concli Leite, Diogo Losch de Oliveira, Carlos-Alberto Gonçalves
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract Background Temporal lobe epilepsy (TLE) is the most common form of partial epilepsy and is accompanied, in one third of cases, by resistance to antiepileptic drugs (AED). Most AED target neuronal activity modulated by ionic channels, and the
Externí odkaz:
https://doaj.org/article/18ec9be05c014d7e8fc0e7bd20cd649e
Autor:
Cristiane Batassini, Núbia Broetto, Lucas Silva Tortorelli, Milene Borsoi, Caroline Zanotto, Fabiana Galland, Tadeu Mello Souza, Marina Concli Leite, Carlos-Alberto Gonçalves
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Both glial fibrillary acidic protein (GFAP) and S100B have been used as markers of astroglial plasticity, particularly in brain injury; however, they do not necessarily change in the same time frame or direction. Herein, we induced a Parkinson’s di
Externí odkaz:
https://doaj.org/article/912aaef15d7b4f3bafc193344905ec9b
Autor:
Larissa Daniele Bobermin, André Quincozes-Santos, Maria Cristina Guerra, Marina Concli Leite, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Carmem Gottfried
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52164 (2012)
Ammonia is implicated as a neurotoxin in brain metabolic disorders associated with hyperammonemia. Acute ammonia toxicity can be mediated by an excitotoxic mechanism, oxidative stress and nitric oxide (NO) production. Astrocytes interact with neurons
Externí odkaz:
https://doaj.org/article/0aed4e5bc8b442099703dcd1981c7503
Autor:
Marina Concli Leite, Jéssica Taday, Carlos Alberto Gonçalves, Leonardo Menezes, Anderson Cigerce, Bruna Schultz
Publikováno v:
Journal of Alzheimer's Disease. 84:1415-1430
One of the changes found in the brain in Alzheimer’s disease (AD) is increased calpain, derived from calcium dysregulation, oxidative stress, and/or neuroinflammation, which are all assumed to be basic pillars in neurodegenerative diseases. The rol
Autor:
Miriara Borges Leal, Marina Concli Leite, Carollina Da Ré, Fabiana Galland, Carlos Alberto Gonçalves, Adriana Fernanda Kuckartz Vizuete, Fernanda Hansen
Publikováno v:
Neurochemical Research. 44:301-311
Astrocytes are the major glial cells in brain tissue and are involved, among many functions, ionic and metabolic homeostasis maintenance of synapses. These cells express receptors and transporters for neurotransmitters, including GABA. GABA signaling
Autor:
Roberto Farina de Almeida, Carine Lampert, Juliana Bender Hoppe, Rachel Krolow, D. Aristimunha, Fabrício do Couto Nicola, Eduardo Farias Sanches, Caroline Peres Klein, Carla Dalmaz, Carlos Alexandre Netto, Natividade de Sá Couto-Pereira, Rafael Oliveira Moraes, Ana Caroline Silva Silveira, Fernanda Carolina Telles da Silva Fróes, Laura Bem Olivo, Giovana Duzzo Gamaro, Ana Paula Toniazzo, Denise Maria Zancan, Danusa Mar Arcego, Fernanda Urruth Fontella, Emily dos Santos Garcia, Marina Concli Leite
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.).
Objective Exposure to artificial sweeteners, such as aspartame, during childhood and adolescence has been increasing in recent years. However, the safe use of aspartame has been questioned owing to its potentially harmful effects on the developing br
Autor:
Cristiane Batassini, Marina Concli Leite, Carlos Alberto Gonçalves, Fabiana Galland, Caroline Zanotto, Bárbara Carolina Federhen, Fernanda Hansen, Patrícia Nardin, Vanessa Fernanda da Silva
Publikováno v:
Molecular Neurobiology. 56:3538-3551
Diabetes mellitus is a metabolic disorder that results in glucotoxicity and the formation of advanced glycated end products (AGEs), which mediate several systemic adverse effects, particularly in the brain tissue. Alterations in glutamatergic neurotr
Autor:
Paulo Alexandre de Oliveira, Nestor Cubas Wendt, Carla Elise Heinz Rieg, Eduardo Benedetti Parisotto, Danilo Wilhelm Filho, Marina Concli Leite, Daiane Cattani, Ariane Zamoner, Rui Daniel Prediger, Guilherme Razzera, Mauren K. Tavares, Patrícia Acordi Cesconetto
Publikováno v:
Toxicology. 387:67-80
We have previously demonstrated that maternal exposure to glyphosate-based herbicide (GBH) leads to glutamate excitotoxicity in 15-day-old rat hippocampus. The present study was conducted in order to investigate the effects of subchronic exposure to
Autor:
João Paulo dos Santos, Marina Concli Leite, Carollina Da Ré, Patrícia Sesterheim, Jéssica Taday, Letícia Rodrigues, Jéssica Maria Souza, Fernanda Carolina Telles da Silva Fróes, Carlos Alberto Gonçalves
Publikováno v:
Behavioural brain research. 379
Peripheral inflammation promotes immune-to-brain communication, mediated by cytokines that affect brain activity. Lipopolysaccharide (LPS) has been widely used to mimic systemic inflammation, and the adipokine leptin, released in this condition, modu