The CaMKII/MLC1 Axis Confers Ca2+-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes

Autor: Maria Stefania Brignone, Angela Lanciotti, Antonio Michelucci, Cinzia Mallozzi, Serena Camerini, Luigi Catacuzzeno, Luigi Sforna, Martino Caramia, Maria Cristina D’Adamo, Marina Ceccarini, Paola Molinari, Pompeo Macioce, Gianfranco Macchia, Tamara Corinna Petrucci, Mauro Pessia, Sergio Visentin, Elena Ambrosini

Publikováno v: Cells, Vol 11, Iss 17, p 2656 (2022)

Astrocytes, the main glial cells of the central nervous system, play a key role in brain volume control due to their intimate contacts with cerebral blood vessels and the expression of a distinctive equipment of proteins involved in solute/water tran

Externí odkaz: https://doaj.org/article/9df8afeeb8104fff9e24465d1bdf7fdc

Advanced Raman Spectroscopy Detection of Oxidative Damage in Nucleic Acid Bases: Probing Chemical Changes and Intermolecular Interactions in Guanosine at Ultralow Concentration

Autor: Simonetta Palleschi, Filomena Mazzei, Enrico Bodo, Paolo Postorino, Chunchun Li, Margherita Bignami, Marina Ceccarini, Claudia Fasolato, Steven E. J. Bell, Francesca Ripanti, Flavia Mazzarda

Publikováno v: Analytical Chemistry
Ripanti, F, Fasolato, C, Mazzarda, F, Palleschi, S, Ceccarini, M, Li, C, Bignami, M, Bodo, E, Bell, S E J, Mazzei, F & Postorino, P 2021, ' Advanced Raman Spectroscopy Detection of Oxidative Damage in Nucleic Acid Bases: Probing Chemical Changes and Intermolecular Interactions in Guanosine at Ultralow Concentration ', Analytical chemistry, vol. 93, no. 31, pp. 10825-10833 . https://doi.org/10.1021/acs.analchem.1c01049

DNA/RNA synthesis precursors are especially vulnerable to damage induced by reactive oxygen species occurring following oxidative stress. Guanosine triphosphates are the prevalent oxidized nucleosites, which can be misincorporated during replication,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb1e183d26e1b1d9993ac96ce5ebd16
http://europepmc.org/articles/PMC8382216

Exploiting SERS sensitivity to monitor DNA aggregation properties

Autor: Paolo Postorino, Debora Caprara, Marina Ceccarini, Angela Capocefalo, Caterina Petrillo, Francesca Ripanti

Publikováno v: International journal of biological macromolecules 170 (2021): 88–93. doi:10.1016/j.ijbiomac.2020.12.039
info:cnr-pdr/source/autori:Caprara D.; Ripanti F.; Capocefalo A.; Ceccarini M.; Petrillo C.; Postorino P./titolo:Exploiting SERS sensitivity to monitor DNA aggregation properties/doi:10.1016%2Fj.ijbiomac.2020.12.039/rivista:International journal of biological macromolecules/anno:2021/pagina_da:88/pagina_a:93/intervallo_pagine:88–93/volume:170

In the last decades, DNA has been considered far more than the system carrying the essential genetic instructions. Indeed, because of the remarkable properties of the base-pairing specificity and thermoreversibility of the interactions, DNA plays a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e786cba4b02abf50a7d6c7a5ddb2b79
https://hdl.handle.net/11697/202824

The Interaction with HMG20a/b Proteins Suggests a Potential Role for β-Dystrobrevin in Neuronal Differentiation

Autor: Benedetta Artegiani, Catherine Labbaye, Pompeo Macioce, Maria Teresa Quaranta, Gianfranco Macchia, Tamara C. Petrucci, Paola Torreri, Antonella Sferra, Marina Ceccarini

Publikováno v: Journal of Biological Chemistry. 285:24740-24750

alpha and beta dystrobrevins are cytoplasmic components of the dystrophin-associated protein complex that are thought to play a role as scaffold proteins in signal transduction and intracellular transport. In the search of new insights into the funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb6c2afca433b43f8190e00d103fc4c
https://doi.org/10.1074/jbc.m109.090654

Expression of dystrophin-associated proteins during neuronal differentiation of P19 embryonal carcinoma cells

Autor: Pompeo Macioce, Tamara C. Petrucci, Barbara Panetta, Marina Ceccarini

Publikováno v: Neuromuscular Disorders. 12:36-48

The dystrophin gene that is defective in Duchenne muscular dystrophy shows a complex transcriptional control based on several promoters driving independent cell-type-specific expression of different isoforms. Dystrophin isoforms together with dystrog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b10ec82938e2be39d67e88af7ffe54f
https://doi.org/10.1016/s0960-8966(01)00230-9