Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marina C Calixto"'
Autor:
Luiz O Leiria, Carolina Sollon, Marina C Calixto, Letícia Lintomen, Fabíola Z Mónica, Gabriel F Anhê, Gilberto De Nucci, Angelina Zanesco, Andrew D Grant, Edson Antunes
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48507 (2012)
Obesity/metabolic syndrome are common risk factors for overactive bladder. This study aimed to investigate the functional and molecular changes of detrusor smooth muscle (DSM) in high-fat insulin resistant obese mice, focusing on the role of protein
Externí odkaz:
https://doaj.org/article/3fd31b1e20ca40359c22230386b9b370
Autor:
Luiz O.S. Leiria, Fernanda M. Arantes-Costa, Marina C. Calixto, Eduardo C. Alexandre, Rodrigo F. Moura, Franco Folli, Carla M. Prado, Marco Antonio Prado, Vania F. Prado, Licio A. Velloso, José Donato Jr., Edson Antunes, Milton A. Martins, Mario J.A. Saad
Publikováno v:
Cell Reports, Vol 11, Iss 6, Pp 934-943 (2015)
Obesity is a major risk factor for asthma, which is characterized by airway hyperreactivity (AHR). In obesity-associated asthma, AHR may be regulated by non-TH2 mechanisms. We hypothesized that airway reactivity is regulated by insulin in the CNS, an
Externí odkaz:
https://doaj.org/article/e62ac39151124fa3ae3ee0ce36d19a1f
Autor:
André L. Rennó, Ana P. Lima-Barbosa, Antonio Condino-Neto, Lineu Baldissera, Dalize M. Squebola-Cola, Marina C. Calixto, Gilberto De Nucci, Edson Antunes, Gabriel Forato Anhê
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 41:86-95
Objectives Activators of soluble guanylyl cyclase (sGC) act preferentially in conditions of enzyme oxidation or haem group removal. This study was designed to investigate the effects of the sGC activator BAY 60-2770 in murine airways inflammation and
Autor:
Diana Majolli André, Luiz O. Leiria, Natalia Tobar, Carolina Sollon, Edson Antunes, Marina C. Calixto, Gabriel Forato Anhê, Eduardo C. Alexandre
Publikováno v:
International Immunopharmacology. 38:298-305
Obesity and insulin resistance have been associated with deterioration in asthma outcomes. High oxidative stress and deficient activation of AMP-activated protein kinase (AMPK) have emerged as important regulators linking insulin resistance and infla
Autor:
Diana Majolli André, Cristina Maki Horimoto, Eduardo C. Alexandre, Marina C. Calixto, Edson Antunes
Publikováno v:
International immunopharmacology. 62
Obesity is linked to worse asthma symptoms. Epigallocatechin-3-gallate (EGCG) reduces airway inflammation, but no study investigated the effects of EGCG on obesity-associated asthma. We aimed here to evaluate the effects of EGCG on allergen-induced a
Autor:
Eduardo C. Alexandre, Edson Antunes, Gabriel Forato Anhê, Marina C. Calixto, Ana C. Antunes Naime, Carolina Sollon, Edith B G Tavares, Diana M. André
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Insulin resistance plays an important role in obesity-associated asthma exacerbations. Using a murine model of allergic airway inflammation, we evaluated the insulin signaling transmission in lungs of obese compared with lean mice. We further evaluat
Autor:
Mario J.A. Saad, Eduardo C. Alexandre, Marco A. M. Prado, Licio A. Velloso, Luiz O. Leiria, Fernanda Magalhães Arantes-Costa, Edson Antunes, Carla Máximo Prado, Franco Folli, Vania F. Prado, Rodrigo Ferreira de Moura, Jose Donato, Milton A. Martins, Marina C. Calixto
Publikováno v:
Cell Reports, Vol 11, Iss 6, Pp 934-943 (2015)
Anatomy and Cell Biology Publications
Anatomy and Cell Biology Publications
SummaryObesity is a major risk factor for asthma, which is characterized by airway hyperreactivity (AHR). In obesity-associated asthma, AHR may be regulated by non-TH2 mechanisms. We hypothesized that airway reactivity is regulated by insulin in the
Autor:
Marina C. Calixto, Fábio H. Silva, André Almeida Schenka, Letícia Lintomen, Haroldo A. Toque, Angelina Zanesco, Edson Antunes, Mario J.A. Saad
Publikováno v:
BJU International. 107:1628-1634
Study Type – Aetiology (case control) Level of Evidence 3b What’s known on the subject? and What does the study add? Erectile dysfunction (ED) is defined as the persistent inability to achieve and/or maintain an erection sufficient for satisfacto
Autor:
Angelina Zanesco, Mario J.A. Saad, Edson Antunes, Letícia Lintomen, André Almeida Schenka, Marina C. Calixto
Publikováno v:
British Journal of Pharmacology. 159:617-625
Background and purpose: Obesity is associated with deterioration in asthma outcomes. Although airways eosinophil accumulation is characteristic of lung allergic diseases, little is known about the influence of obesity on the allergic eosinophil traff
Publikováno v:
Urology. 86(2)
To evaluate the effects of treatment with metformin on a murine model of obesity-associated erectile dysfunction.C57BL/6 male mice were fed for 10 weeks with standard chow or high-fat diet. Lean and obese mice were treated with the insulin sensitizer