Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Marina Breuhaus"'
Autor:
Nicole Barucci, Herbert Ogutu, Laurel Sweet, Ronda Ott-Morgan, Louis-David Cantin, Yaxin Li, James N. Livingston, Philip Wickens, Lei Zhu, Sidney X. Liang, Jennifer Burke, Timothy B. Lowinger, Zhonghua Zhang, Bullock William H, Michelle Daly, Robert Schoenleber, Lynn Decarr, Steven Magnuson, Adrian Tersteegen, Ann Gore-Willse, Ellalahewage Kumarasinghe, Alan Olague, Jian Zhu, Marina Breuhaus, David E. Gunn, Margit L. MacDougall, Thomas H. Claus, Helana Hoover-Litty
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2869-2873
Modulation of cAMP levels has been linked to insulin secretion in preclinical animal models and in humans. The high expression of PDE-10A in pancreatic islets suggested that inhibition of this enzyme may provide the necessary modulation to elicit inc