Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Marina Bayeva"'
Autor:
Marina Bayeva, Edwin H. Cook
Early in psychiatric genetic research, the field was drawn into the ‘nature versus nurture’ controversy in which the contribution of heritable factors was argued to be negligible to sufficient. This debate was fuelled by divergent conceptualizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::184dfba886a45670245f9d33d9f8200a
https://doi.org/10.1093/med/9780198836506.003.0004
https://doi.org/10.1093/med/9780198836506.003.0004
Autor:
Jason S. Shapiro, Brian N. Finck, Marina Bayeva, Hsiang-Chun Chang, Jason A. Wertheim, Perry J. Blackshear, Adam De Jesus, Konrad T Sawicki, Hossein Ardehali
The role of posttranscriptional metabolic gene regulatory programs in diabetes is not well understood. Here, we show that the RNA-binding protein tristetraprolin (TTP) is reduced in the livers of diabetic mice and humans and is transcriptionally indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a143b9bebe81ff36abff64082d2f1006
https://europepmc.org/articles/PMC6124529/
https://europepmc.org/articles/PMC6124529/
Autor:
Issam Ben-Sahra, Deborah J. Stumpo, Paul T. Schumacker, Ting Liu, Hsiang-Chun Chang, Hossein Ardehali, Lucía Ramos-Alonso, Konrad T Sawicki, Xinghang Jiang, Sergi Puig, Marina Bayeva, Hidemichi Kouzu, María Teresa Martínez-Pastor, Perry J. Blackshear, Chunlei Chen, Sumeyye Yar, Jason S. Shapiro, Tatsuya Sato
Cells respond to iron deficiency by activating iron-regulatory proteins to increase cellular iron uptake and availability. However, it is not clear how cells adapt to conditions when cellular iron uptake does not fully match iron demand. Here, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbea03d0f6fbccf02abbaf22acc7f923
https://europepmc.org/articles/PMC6142244/
https://europepmc.org/articles/PMC6142244/
Publikováno v:
Journal of the American College of Cardiology. 61(18):1884-1893
Objectives The goal of this study was to characterize the regulation of heme and non-heme iron in human failing hearts. Background Iron is an essential molecule for cellular physiology, but in excess it facilitates oxidative stress. Mitochondria are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f5ad59c3087acb5781da7ee3da5bc4
Autor:
Hossein Ardehali, Hsiang-Chun Chang, Sergi Puig, Marina Bayeva, Perry J. Blackshear, Sonika Patial, Arineh Khechaduri
Publikováno v:
Cell Metabolism. 16(5):645-657
SummaryIron is an essential cofactor with unique redox properties. Iron-regulatory proteins 1 and 2 (IRP1/2) have been established as important regulators of cellular iron homeostasis, but little is known about the role of other pathways in this proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823569244f79def805ebab8f62e9df83
Autor:
Rongxue Wu, Hsiang Chun Chang, Minh Tran, Kusum Chawla, Arineh Khechaduri, Xiaomeng Chai, Mohsen Ghanefar, Marina Bayeva, Cory Wagg, Frank Gonzalez, Gary Lopaschuk, Hossein Ardehali
Publikováno v:
Circulation. 130
Background: Metabolic changes decrease cardiac efficiency and energetics in diabetes. Impaired hypoxia inducible factor (HIF) signaling may contribute to cardiac metabolic abnormalities. ARNT, also known as HIF1β, is a transcription factor that regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e761da4a9e8692b7e05a82706c2c1911
https://doi.org/10.1161/circ.130.suppl_2.15414
https://doi.org/10.1161/circ.130.suppl_2.15414
Autor:
Cory S. Wagg, Kusum Chawla, Xiaomeng Chai, Hsiang-Chun Chang, Hossein Ardehali, Rongxue Wu, Minh Tran, Xinghang Jiang, Marina Bayeva, Mohsen Ghanefar, Frank J. Gonzalez, Arineh Khechaduri, Gary D. Lopaschuk
Patients with type 2 diabetes often present with cardiovascular complications; however, it is not clear how diabetes promotes cardiac dysfunction. In murine models, deletion of the gene encoding aryl hydrocarbon nuclear translocator (ARNT, also known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff200ca90dece3b3cae9534f6374f919
https://europepmc.org/articles/PMC4347233/
https://europepmc.org/articles/PMC4347233/
Publikováno v:
Circulation. Heart failure. 7(4)
Heart failure is a leading cause of healthcare expenditures, hospitalization, and mortality in developed countries, and its burden is growing globally.1 With the aging of the population and increasing prevalence of chronic diseases, including hyperte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35668595d982d5782905b0447eb5853
https://pubmed.ncbi.nlm.nih.gov/25028350
https://pubmed.ncbi.nlm.nih.gov/25028350
Autor:
Hossein Ardehali, Marina Bayeva
Publikováno v:
Manual of Research Techniques in Cardiovascular Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b0a41a6c883a13dffdebea45864795
https://doi.org/10.1002/9781118495148.ch47
https://doi.org/10.1002/9781118495148.ch47
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Heart disease is the leading cause of death in patients with diabetes.[1][1] Although advances in medical management and lifestyle interventions have reduced cardiovascular mortality in diabetic patients by as much as 40% over the last decade, the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b16f44ca09b99d0fdc54679a6f132d
https://doi.org/10.1161/jaha.113.000433
https://doi.org/10.1161/jaha.113.000433