Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Marina Amaral Alves"'
Autor:
Aline Cavalcanti de Queiroz, Gisele Barbosa, Victória Regina Thomaz de Oliveira, Hélio de Mattos Alves, Marina Amaral Alves, Vanessa Carregaro, João Santana da Silva, Eliezer Jesus Barreiro, Magna Suzana Alexandre-Moreira, Lidia Moreira Lima
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Leishmaniasis is a public health issue. It is among the top five parasitic illnesses worldwide and is one of the most neglected diseases. The current treatment disease includes limitations of toxicity, variable efficacy, high costs and inconvenient d
Externí odkaz:
https://doaj.org/article/7a9c0c6951494a1d9670fe9d11998b34
Autor:
Matilda Kråkström, Alex M. Dickens, Marina Amaral Alves, Sofia D. Forssten, Arthur C. Ouwehand, Tuulia Hyötyläinen, Matej Orešič, Santosh Lamichhane
Publikováno v:
Metabolites, Vol 13, Iss 3, p 355 (2023)
Current evidence suggests that gut microbiome-derived lipids play a crucial role in the regulation of host lipid metabolism. However, not much is known about the dynamics of gut microbial lipids within the distinct gut biogeographic. Here we applied
Externí odkaz:
https://doaj.org/article/b9072a4beacc4cd2bb0377f6183427e2
Autor:
Santosh Lamichhane, Partho Sen, Marina Amaral Alves, Henrique C. Ribeiro, Peppi Raunioniemi, Tuulia Hyötyläinen, Matej Orešič
Publikováno v:
Metabolites, Vol 11, Iss 1, p 55 (2021)
Various studies aiming to elucidate the role of the gut microbiome-metabolome co-axis in health and disease have primarily focused on water-soluble polar metabolites, whilst non-polar microbial lipids have received less attention. The concept of micr
Externí odkaz:
https://doaj.org/article/e90cf22ac41e4f888246ace1a00e9979
Autor:
Yolanda Karla Cupertino da Silva, Christian Tadeo Moreno Reyes, Gildardo Rivera, Marina Amaral Alves, Eliezer J. Barreiro, Magna Suzana Alexandre Moreira, Lídia Moreira Lima
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 8456-8471 (2014)
Different chemotypes are described as anti-inflammatory. Among them the N-acylhydrazones (NAH) are highlighted by their privileged structure nature, being present in several anti-inflammatory drug-candidates. In this paper a series of functionalized
Externí odkaz:
https://doaj.org/article/a8283f0c222d4e588cd66bc0c8dd39f7
Autor:
Matilda Kråkström, Alex M. Dickens, Marina Amaral Alves, Sofia D. Forssten, Arthur C. Ouwehand, Tuulia Hyötyläinen, Matej Orešič, Santosh Lamichhane
Current evidence suggests that gut microbiome derived lipids play crucial role in the regulation of host lipid metabolism. However, not much is known about the dynamics of gut microbial lipids within the distinct gut biogeographic. Here we employed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af1efa2262b63c805dddc9651a20c9eb
https://doi.org/10.1101/2022.12.13.520210
https://doi.org/10.1101/2022.12.13.520210
Autor:
Santosh Lamichhane, Partho Sen, Alex M. Dickens, Marina Amaral Alves, Taina Härkönen, Jarno Honkanen, Tommi Vatanen, Ramnik J. Xavier, Tuulia Hyötyläinen, Mikael Knip, Matej Orešič
The gut microbiota is crucial in the regulation of bile acid (BA) metabolism. However, not much is known about the regulation of BAs during progression to type 1 diabetes (T1D). Here, we analyzed serum and stool BAs in longitudinal samples collected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71d85eece36a20345563b13686734fa
http://hdl.handle.net/10138/351303
http://hdl.handle.net/10138/351303
Autor:
Eduardo Caio Torres-Santos, Débora de Souza Costa, Danyelle C. Santos, Valter Viana Andrade-Neto, Thaissa L. Silva, Marina Amaral Alves, Alan H. Fairlamb, Edézio Ferreira Cunha-Júnior, Paulo R. R. Costa, Marília O. F. Goulart, Ayres G. Dias, Susan Wyllie, Juliana da Silva Pacheco
Publikováno v:
ACS Med Chem Lett
[Image: see text] 5-Nitro-furan nitrones (1) and 5-nitro-thiophene nitrones (2) were synthesized in one step. Compounds 1a–c had the most potent leishmanicidal activity against intracellular amastigote forms of Leishmania amazonensis and L. infantu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36771859ab18b4684d9de6f221ab55bf
https://doi.org/10.1021/acsmedchemlett.1c00193
https://doi.org/10.1021/acsmedchemlett.1c00193
Autor:
Felipe Raposo Passos Mansoldo, Rafael Garrett, Veronica da Silva Cardoso, Marina Amaral Alves, Alane Beatriz Vermelho
Publikováno v:
Analytica chimica acta. 1232
Several areas such as microbiology, botany, and medicine use genetic information and computational tools to organize, classify and analyze data. However, only recently has it been possible to obtain the chemical ontology of metabolites computationall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c83da6f16fd7e811883b4d30a0a7bf2
https://pubmed.ncbi.nlm.nih.gov/36257759
https://pubmed.ncbi.nlm.nih.gov/36257759
Autor:
Lana Resende de ALMEIDA, Marina Amaral ALVES, Ana Maria Obino MASTELLA, Rafael GARRETT, Maria João Ramos PEREIRA
Publikováno v:
Integrative zoologyREFERENCES.
Chemical profiles of non-invasive biological material, such as feces, have great potential to study elusive animals or those with low population densities. Here, we use a metabolomic approach to evaluate Neotropical mustelids as a biological model to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189502118b6cc8341f1efaa1083f3e69
https://pubmed.ncbi.nlm.nih.gov/35275446
https://pubmed.ncbi.nlm.nih.gov/35275446
Autor:
Marina Amaral Alves, Carlos A. M. Fraga, Patricia Dias Fernandes, Pedro de Sena Murteira Pinheiro, Carlos Mauricio R. Sant'Anna, Fernanda S. Sagrillo, Daniel Alencar Rodrigues, Sreekanth Thota, Fabiana Sélos Guerra, Lorrane S. Chaves
Publikováno v:
ChemMedChem. 15:539-551
Targeting histone deacetylases (HDACs) and phosphatidylinositol 3-kinases (PI3Ks) is a very promising approach for cancer treatment. This manuscript describes the design, synthesis, in vitro pharmacological profile, and molecular modeling of a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaaf213aecc07520225239a0f628f6d3
https://doi.org/10.1002/cmdc.201900716
https://doi.org/10.1002/cmdc.201900716