Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins

Autor: Mathilde Romagnoli, Stéphanie Cagnet, Aurélie Chiche, Laura Bresson, Sylvain Baulande, Pierre de la Grange, Adèle De Arcangelis, Maaike Kreft, Elisabeth George-Labouesse, Arnoud Sonnenberg, Marie-Ange Deugnier, Karine Raymond, Marina A. Glukhova, Marisa M. Faraldo

Publikováno v: Stem Cell Reports, Vol 12, Iss 4, Pp 831-844 (2019)

Summary: Integrins, which bind laminin, a major component of the mammary basement membrane, are strongly expressed in basal stem cell-enriched populations, but their role in controlling mammary stem cell function remains unclear. We found that stem c

Externí odkaz: https://doaj.org/article/452bc3bcc42846a7b2184f343579abd9

Mammary Stem Cells

Autor: Marie-Ange Deugnier, Marisa M. Faraldo, Marina A. Glukhova

Publikováno v: Stem Cell Biology and Regenerative Medicine ISBN: 9781003339601

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad1616326cb3bbadf8c6014efe33d9d7
https://doi.org/10.1201/9781003339601-20

Orthotopic Transplantation of Mouse Mammary Epithelial Cells

Autor: Marisa M, Faraldo, Marina A, Glukhova, Marie-Ange, Deugnier

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2471

The orthotopic transplantation assay has provided important insights into mammary development, stem cell function, and tumorigenesis. Technically, it consists in grafting mammary tissue fragments, organoids, mammospheres, or isolated cells into the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb2b10b3ea852869819a599ab43dc594
https://pubmed.ncbi.nlm.nih.gov/35175594

Paracrine Met signaling triggers epithelial–mesenchymal transition in mammary luminal progenitors, affecting their fate

Autor: Amandine Di-Cicco, Valérie Petit, Aurélie Chiche, Laura Bresson, Mathilde Romagnoli, Véronique Orian-Rousseau, Maria dM Vivanco, Daniel Medina, Marisa M Faraldo, Marina A Glukhova, Marie-Ange Deugnier

Publikováno v: eLife, Vol 4 (2015)

HGF/Met signaling has recently been associated with basal-type breast cancers, which are thought to originate from progenitor cells residing in the luminal compartment of the mammary epithelium. We found that ICAM-1 efficiently marks mammary luminal

Externí odkaz: https://doaj.org/article/573fecdc0c5a4403bdebfb77400a900b

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling

Autor: Pierre de la Grange, Marie-Ange Deugnier, Marisa M. Faraldo, Marina A. Glukhova, Laura Sesma-Sanz, Aurélie Chiche, Amandine Di-Cicco, Laura Bresson

Publikováno v: Breast Cancer Research
Breast Cancer Research, BioMed Central, 2019, 21, pp.13. ⟨10.1186/s13058-019-1101-8⟩
Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Breast Cancer Research, 2019, 21, pp.13. ⟨10.1186/s13058-019-1101-8⟩

Background The adult mammary epithelium is composed of basal and luminal cells. The luminal lineage comprises two major cell populations, positive and negative for estrogen and progesterone receptors (ER and PR, respectively), both containing clonoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991fdea24bb99c05b4887f409f8069ad
https://hal.sorbonne-universite.fr/hal-01996712