Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marina A, Afanasyeva"'
Publikováno v:
Journal of obstetrics and women's diseases. 71:85-94
One of the major issues in modern midwifery is premature birth, which is often the result of premature rupture of membranes. Currently known methods for predicting premature rupture of membranes do not have sufficient predictive value in preterm preg
Autor:
Marina A Afanasyeva, Lidia V Putlyaeva, Denis E Demin, Ivan V Kulakovskiy, Ilya E Vorontsov, Marina V Fridman, Vsevolod J Makeev, Dmitry V Kuprash, Anton M Schwartz
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172681 (2017)
We studied functional effect of rs12722489 single nucleotide polymorphism located in the first intron of human IL2RA gene on transcriptional regulation. This polymorphism is associated with multiple autoimmune conditions (rheumatoid arthritis, multip
Externí odkaz:
https://doaj.org/article/1b53b0d793e748d19e0ebb55e673d7eb
Autor:
Alina S. Ustiugova, Ekaterina M. Dvorianinova, Nataliya V. Melnikova, Alexey A. Dmitriev, Dmitry V. Kuprash, Marina A. Afanasyeva
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1869:166649
Publikováno v:
Молекулярная биология. 54:826-836
Currently only a small fraction of the proteins encoded in the human genome serve as pharmaceutical targets. Genome-wide association studies are a powerful tool to uncover new genetic loci responsible for predisposition to complex diseases, such as a
Autor:
Marina A. Afanasyeva, Dmitry V. Kuprash, D E Demin, A. V. Bogolyubova, Lidia V. Putlyaeva, Alina S. Ustiugova, A. M. Schwartz, Andrew R. Zaretsky, Vladimir E. Vanushko, M M Prokofjeva, Arthur T. Kopylov, P. V. Belousov, Natalya V. Severskaia, Nina Y. Dvinskikh, Kirill V. Lanshchakov, A N Uvarova, K. A. Tatosyan, Ekaterina O. Gubernatorova, Alexander Y. Abrosimov, Egle-Marija Ramanauskaite
Publikováno v:
Cancer Letters. 467:96-106
Tumor-associated antigen (TAA)-specific autoantibodies have been widely implicated in cancer diagnosis. However, cancer cell lines that are typically exploited as candidate TAA sources in immunoproteomic studies may fail to accurately represent the a
Autor:
Anna V. Klepikova, Marina A. Afanasyeva, L V Putlyaeva, A N Uvarova, A M Gorbachova, Alina S. Ustiugova, K. A. Tatosyan, A. M. Schwartz, P. V. Belousov, D E Demin, M M Prokofjeva
Publikováno v:
Biochemistry (Moscow). 84:416-425
The Q61R mutation of the NRAS gene is one of the most frequent driver mutations of thyroid cancer. Tumors with this mutation are characterized by invasion into blood vessels and formation of distant metastases. To study the role of this mutation in t
Autor:
Marina A Afanasyeva, Liudmila V Britanova, Kirill V Korneev, Nikita A Mitkin, Anna A Kuchmiy, Dmitry V Kuprash
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98349 (2014)
Clusterin is a multifunctional protein that participates in tissue remodeling, apoptosis, lipid transport, complement-mediated cell lysis and serves as an extracellular chaperone. The role of clusterin in cancer and neurodegeneration has been extensi
Externí odkaz:
https://doaj.org/article/70e6d2a414c248a6845bf69298348a81
Autor:
Marina A. Afanasyeva, Dmitry V. Kuprash, Vsevolod V. Pavshintsev, Konstantin A. Rumyantsev, A N Uvarova, A. M. Schwartz, Nikita A. Mitkin, Kirill V. Korneev, Murad Vagida, Alisa M. Muratova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3211-3220
CD58 is expressed on the surface of antigen-presenting cells, including B-cells, and provides co-stimulation to regulatory T-cells (Treg) through CD2 receptor binding. Tregs appear to be essential suppressors of tissue-specific autoimmune responses.
Autor:
A. D. Beniaminov, Marina A. Afanasyeva, Khava S. Vishnyakova, Alexei A. Adzhubei, E. B. Dashinimaev, G. A. Puzanov, Yegor E. Yegorov, Tatiana T. Kondratieva, George S. Krasnov, V. N. Senchenko
Publikováno v:
Bioscience Reports
Non-Small Cell Lung Cancer (NSCLC) is responsible for the majority of deaths caused by cancer. Small C-terminal domain (CTD) phosphatases (SCP), CTDSP1, CTDSP2 and CTDSPL (CTDSPs) belong to SCP/CTDSP subfamily and are involved in many vital cellular
Autor:
A. M. Schwartz, Nikita A. Mitkin, Marina A. Afanasyeva, Dmitry V. Kuprash, Alisa M. Gorbacheva, Ivan V. Kulakovskiy, Ekaterina N. Sviriaeva, A N Uvarova, O. L. Polanovsky, Kirill V. Korneev, Alina S. Ustiugova
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1866(3)
Toll-like receptor 4 (TLR4) is an innate immunity receptor predominantly expressed on myeloid cells and involved in the development of various diseases, many of them with complex genetics. Here we present data on functionality of single nucleotide po