Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Marina, Scardigli"'
Autor:
Curzio Checcucci, Bridget Wicinski, Giacomo Mazzamuto, Marina Scardigli, Josephine Ramazzotti, Niamh Brady, Francesco S. Pavone, Patrick R. Hof, Irene Costantini, Paolo Frasconi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract 3D reconstruction of human brain volumes at high resolution is now possible thanks to advancements in tissue clearing methods and fluorescence microscopy techniques. Analyzing the massive data produced with these approaches requires automati
Externí odkaz:
https://doaj.org/article/7a03e70b94084892bc125093f3c41c3b
Autor:
Luca Pesce, Marina Scardigli, Vladislav Gavryusev, Annunziatina Laurino, Giacomo Mazzamuto, Niamh Brady, Giuseppe Sancataldo, Ludovico Silvestri, Christophe Destrieux, Patrick R. Hof, Irene Costantini, Francesco S. Pavone
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
An optimized clearing approach, named SHORT, applied to thick sections of human cortical tissue allows reconstruction of large portions of the tissues using light-sheet fluorescence microscopy, by performing multicolor immunostaining and multirounds.
Externí odkaz:
https://doaj.org/article/e482466fc9d14136bc40195885614206
Autor:
Marina Scardigli, Luca Pesce, Niamh Brady, Giacomo Mazzamuto, Vladislav Gavryusev, Ludovico Silvestri, Patrick R. Hof, Christophe Destrieux, Irene Costantini, Francesco S. Pavone
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
The combination of tissue clearing techniques with advanced optical microscopy facilitates the achievement of three-dimensional (3D) reconstruction of macroscopic specimens at high resolution. Whole mouse organs or even bodies have been analyzed, whi
Externí odkaz:
https://doaj.org/article/7792613291ca417ab4f5bdea08653169
Autor:
Raffaele Coppini, MD, PhD, Cecilia Ferrantini, MD, PhD, Josè Manuel Pioner, PhD, Lorenzo Santini, MS, Zhinuo J. Wang, PhD, Chiara Palandri, MS, Marina Scardigli, PhD, Giulia Vitale, MS, Leonardo Sacconi, PhD, Pierluigi Stefàno, MD, Laura Flink, MD, Katherine Riedy, MD, Francesco Saverio Pavone, PhD, Elisabetta Cerbai, PhD, Corrado Poggesi, MD, Alessandro Mugelli, MD, Alfonso Bueno-Orovio, PhD, Iacopo Olivotto, MD, Mark V. Sherrid, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 795-813 (2019)
Summary: Disopyramide is effective and safe in patients with obstructive hypertrophic cardiomyopathy. However, its cellular and molecular mechanisms of action are unknown. We tested disopyramide in cardiomyocytes from the septum of surgical myectomy
Externí odkaz:
https://doaj.org/article/383410aaa4f04130b18b186ad5f7d1d6
Autor:
Giacomo Mazzamuto, Ludovico Silvestri, Giuseppe Sancataldo, Vladislav Gavryusev, Marina Scardigli, Irene Costantini, Francesco S. Pavone
Publikováno v:
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXX.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::934994d314f4bac4ce3df513f28dfd98
https://doi.org/10.1117/12.2650374
https://doi.org/10.1117/12.2650374
Autor:
Irene Costantini, Marina Scardigli, Josephine Ramazzotti, Niamh Brady, Franco Cheli, Giacomo Mazzamuto, Filippo Castelli, Curzio Checcucci, Ludovico Silvestri, Paolo Frasconi, Francesco S. Pavone
Publikováno v:
Neural Imaging and Sensing 2023.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5997cfab0d88753ad06e826badb066
https://doi.org/10.1117/12.2649323
https://doi.org/10.1117/12.2649323
Autor:
Sören Brandenburg, Jan Pawlowitz, Vanessa Steckmeister, Hariharan Subramanian, Dennis Uhlenkamp, Marina Scardigli, Mufassra Mushtaq, Saskia I. Amlaz, Tobias Kohl, Jörg W. Wegener, Demetrios A. Arvanitis, Despina Sanoudou, Leonardo Sacconi, Gerd Hasenfuß, Niels Voigt, Viacheslav O. Nikolaev, Stephan E. Lehnart
Publikováno v:
Journal of Molecular and Cellular Cardiology. 165:141-157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::facbdf1c192e2b5047b1770eb61b2bd1
https://doi.org/10.1016/j.yjmcc.2022.01.003
https://doi.org/10.1016/j.yjmcc.2022.01.003
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Asynchronous Ca2+ release promotes non-homogeneous myofilament activation, leading to mechanical dysfunction, as well as initiation of propagated calcium waves and arrhythmias. Recent advances in microscopy techniques have allowed for optical recordi
Externí odkaz:
https://doaj.org/article/db474991e8f14f528cf82ce2906f5b3e
Autor:
Sören Brandenburg, Jan Pawlowitz, Funsho E. Fakuade, Daniel Kownatzki-Danger, Tobias Kohl, Gyuzel Y. Mitronova, Marina Scardigli, Jakob Neef, Constanze Schmidt, Felix Wiedmann, Francesco S. Pavone, Leonardo Sacconi, Ingo Kutschka, Samuel Sossalla, Tobias Moser, Niels Voigt, Stephan E. Lehnart
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Rationale: Recently, abundant axial tubule (AT) membrane structures were identified deep inside atrial myocytes (AMs). Upon excitation, ATs rapidly activate intracellular Ca2+ release and sarcomeric contraction through extensive AT junctions, a cell-
Externí odkaz:
https://doaj.org/article/a7e5511ae07e47db91b405f3d2b0cd8e
Autor:
Francesco Giardini, Valentina Biasci, Marina Scardigli, Francesco S. Pavone, Gil Bub, Leonardo Sacconi
Publikováno v:
Methods and Protocols, Vol 2, Iss 1, p 7 (2019)
Optogenetics is an emerging method that uses light to manipulate electrical activity in excitable cells exploiting the interaction between light and light-sensitive depolarizing ion channels, such as channelrhodopsin-2 (ChR2). Initially used in the n
Externí odkaz:
https://doaj.org/article/e9c10b46ee9443e5abf7ab9183dd9add