Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Marina, Jerebtsova"'
Autor:
Namita Kumari, Asrar Ahmad, Clemilson Berto-Junior, Andrey Ivanov, Fayuan Wen, Xionghao Lin, Sharmin Diaz, Iheanyi Okpala, James G. Taylor, VI, Marina Jerebtsova, Sergei Nekhai
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108813- (2024)
Summary: Sickle cell disease (SCD) is characterized by hemolysis, vaso-occlusion, and ischemia. HIV-1 infection was previously shown to be suppressed in SCD PBMCs. Here, we report that HIV-1 suppression is attributed to the increased expression of ir
Externí odkaz:
https://doaj.org/article/4bbe06d506ad444d967a38da2597546b
Autor:
Nowah Afangbedji, Marina Jerebtsova
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Sickle cell disease (SCD) is a group of inherited blood disorders affecting the β-globin gene, resulting in the polymerization of hemoglobin and subsequent sickling of the red blood cell. Renal disease, the most common complication in SCD, begins in
Externí odkaz:
https://doaj.org/article/b305f6f889ea472091da6553695bf22b
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 7 (2021)
People of African ancestry living with the human immunodeficiency virus-1 (HIV-1) are at risk of developing HIV-associated nephropathy (HIVAN). Children with HIVAN frequently show high plasma fibroblast growth factor-2 (FGF-2) levels; however, the ro
Externí odkaz:
https://doaj.org/article/8c1e6fcf93e64708b592aee875841085
Autor:
Nowah Afangbedji, Namita Kumari, Sharmin Diaz, Fayuan Wen, James G. Taylor, Sergei Nekhai, Marina Jerebtsova
Publikováno v:
Blood Advances. 7:1854-1857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19269a6d15ef9193cff4b8c50eabef57
https://doi.org/10.1182/bloodadvances.2022008374
https://doi.org/10.1182/bloodadvances.2022008374
Publikováno v:
Physiology. 38
BACKGROUND: More than 50% of sickle cell anemia (SCA) patients develop chronic kidney disease (CKD). The mechanism of CKD is multifactorial and is not yet fully understood. SCA is a vasculopathy associated with multiple mechanisms driven by cell-free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d85041556a46372273615d0f3204ccd
https://doi.org/10.1152/physiol.2023.38.s1.5734971
https://doi.org/10.1152/physiol.2023.38.s1.5734971
Autor:
Namita Kumari, Tatiana Ammosova, Sharmin Diaz, Xionghao Lin, Xiaomei Niu, Andrey Ivanov, Marina Jerebtsova, Subhash Dhawan, Patricia Oneal, Sergei Nekhai
Publikováno v:
Blood Advances, Vol 1, Iss 3, Pp 170-183 (2016)
Abstract: The low incidence of HIV-1 infection in patients with sickle cell disease (SCD) and inhibition of HIV-1 replication in vitro under the conditions of low intracellular iron or heme treatment suggests a potential restriction of HIV-1 infectio
Externí odkaz:
https://doaj.org/article/2e2cc677196b44009c2cc815a6598f35
Publikováno v:
Viruses, Vol 12, Iss 3, p 277 (2020)
While antiretroviral therapy increases the longevity of people living with HIV (PLWH), about 30% of this population suffers from three or more concurrent comorbidities, whose mechanisms are not well understood. Chronic activation and dysfunction of t
Externí odkaz:
https://doaj.org/article/21553c25a6514d20be20f92ea9294516
Publikováno v:
Viruses, Vol 12, Iss 2, p 204 (2020)
Human immunodeficiency virus (HIV)-infected individuals treated with anti-retroviral therapy often develop chronic non-infectious lung disease. To determine the mechanism of HIV-1-associated lung disease we evaluated the dynamics of lung leukocytes i
Externí odkaz:
https://doaj.org/article/23a98883977248138eb2f36899adbfbe
Autor:
Alfia Khaibullina, Elena A. Adjei, Nowah Afangbedji, Andrey Ivanov, Namita Kumari, Luis E.F. Almeida, Zenaide M.N. Quezado, Sergei Nekhai, Marina Jerebtsova
Publikováno v:
Haematologica, Vol 103, Iss 5 (2018)
Sickle cell disease patients are at increased risk of developing a chronic kidney disease. Endothelial dysfunction and inflammation associated with hemolysis lead to vasculopathy and contribute to the development of renal disease. Here we used a Town
Externí odkaz:
https://doaj.org/article/9e5ea2f79f0b41c7b6fc46474f12e3f2
Publikováno v:
Blood Advances.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e1a07ec194eb7aaee40ee9721cdc2db
https://doi.org/10.1182/bloodadvances.2022008006
https://doi.org/10.1182/bloodadvances.2022008006