Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marina, Gorbatyuk"'
Autor:
Trong Thuan Ung, Christopher R. Starr, Assylbek Zhylkibayev, Irina Saltykova, Marina Gorbatyuk
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4716 (2024)
Inherited retinal degeneration (RD) constitutes a heterogeneous group of genetic retinal degenerative disorders. The molecular mechanisms underlying RD encompass a diverse spectrum of cellular signaling, with the unfolded protein response (UPR) ident
Externí odkaz:
https://doaj.org/article/d793b338fed6434a8e3af551465f7702
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Activation of the endoplasmic reticulum (ER) stress and ER stress response, also known as the unfolded protein response (UPR), is common to various degenerative disorders. Therefore, signaling components of the UPR are currently emerging as potential
Externí odkaz:
https://doaj.org/article/68f68e9cce6f4522acaa724002e29ee4
Autor:
Yogesh Bhootada, Pravallika Kotla, Sergei Zolotukhin, Oleg Gorbatyuk, Zsuzsanna Bebok, Mohammad Athar, Marina Gorbatyuk
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154779 (2016)
T17M rhodopsin expression in rod photoreceptors leads to severe retinal degeneration and is associated with the activation of ER stress related Unfolded Protein Response (UPR) signaling. Here, we show a novel role of a UPR transcription factor, ATF4,
Externí odkaz:
https://doaj.org/article/83a236745f18415f9c9945e49c49177a
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e63205 (2013)
Despite the proposed link between ablation of the CHOP protein and delay of the onset of ER stress-mediated disorders including diabetes, Alzheimer Disease, and cardiac hypertrophy, the role of CHOP protein in photoreceptor cell death associated with
Externí odkaz:
https://doaj.org/article/4efc6c92b274469d9fff35f72cf18931
Publikováno v:
Journal of cellular physiology. 232(3)
Neuronatin (NNAT) was first identified as a brain-specific gene crucial for brain development. Over the years, NNAT has been studied in different developing and post-developed tissues and organs. While NNAT manifests functional and structural similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fef2683b76eb036594565ffbc82ced3
https://pubmed.ncbi.nlm.nih.gov/27442611
https://pubmed.ncbi.nlm.nih.gov/27442611
Autor:
Noman Kadhom, Jan-Willem Taanman, Pierre Rustin, Marina Gorbatyuk, Antoni Barrientos, Patrick Niaudet, Anne Lombès, Isabelle Valnot, Hélène Ogier de Baulny, Alexander Tzagoloff, Agnès Rötig, Pascale de Lonlay, Dominique Chretien, Arnold Munnich, Emmanuel Benayoun
Publikováno v:
Nature Genetics. 29:57-60
Complex III (CIII; ubiquinol cytochrome c reductase of the mitochondrial respiratory chain) catalyzes electron transfer from succinate and nicotinamide adenine dinucleotide-linked dehydrogenases to cytochrome c. CIII is made up of 11 subunits, of whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc1e36e5008c3294f1d1681b62afec7
https://doi.org/10.1038/ng706
https://doi.org/10.1038/ng706
Autor:
Alexander Tzagoloff, Agnès Rötig, Antonio Barrientos, Jan-Willem Taanman, Blandine Mehaye, Jürgen Christoph Von Kleist-Retzow, Pierre Rustin, Marina Gorbatyuk, Isabelle Valnot, Arnold Munnich
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
Cytochrome c oxidase (COX) defects are found in a clinically and genetically heterogeneous group of mitochondrial disorders. To date, mutations in only two nuclear genes causing COX deficiency have been described. We report here a genetic linkage stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2bdf06252e82994a4b003d25c377e2
https://doi.org/10.1093/hmg/9.8.1245
https://doi.org/10.1093/hmg/9.8.1245
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 252
Hammerhead ribozymes are small, catalytic RNAs that can be designed to effectively inhibit gene expression in an allele-specific manner. It is the high level of sequence discrimination, coupled with the minimal cleavage-site requirements of hammerhea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a593905543b6168256f345f394453fae
https://pubmed.ncbi.nlm.nih.gov/15017052
https://pubmed.ncbi.nlm.nih.gov/15017052
Autor:
Marina Gorbatyuk, Gorbatyuk, O.
Publikováno v:
Scopus-Elsevier
Molecular Vision
Molecular Vision
Recently published literature has provided evidence that the unfolded protein response (UPR) is involved in the development of retinal degeneration. The scope of these studies encompassed diabetic retinopathy, retinopathy of prematurity, glaucoma, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28f0cf622eaa62429361132e2c3bb96f
http://www.scopus.com/inward/record.url?eid=2-s2.0-84884388881&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-84884388881&partnerID=MN8TOARS
