Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Marin van Heel"'
Autor:
Pavel Afanasyev, Charlotte Seer-Linnemayr, Raimond B. G. Ravelli, Rishi Matadeen, Sacha De Carlo, Bart Alewijnse, Rodrigo V. Portugal, Navraj S. Pannu, Michael Schatz, Marin van Heel
Publikováno v:
IUCrJ, Vol 4, Iss 5, Pp 678-694 (2017)
Single-particle cryogenic electron microscopy (cryo-EM) can now yield near-atomic resolution structures of biological complexes. However, the reference-based alignment algorithms commonly used in cryo-EM suffer from reference bias, limiting their app
Externí odkaz:
https://doaj.org/article/84b5977dcdf0496880072bec08d4db4e
Autor:
Ester Vázquez-Fernández, Matthijn R Vos, Pavel Afanasyev, Lino Cebey, Alejandro M Sevillano, Enric Vidal, Isaac Rosa, Ludovic Renault, Adriana Ramos, Peter J Peters, José Jesús Fernández, Marin van Heel, Howard S Young, Jesús R Requena, Holger Wille
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005835 (2016)
The structure of the infectious prion protein (PrPSc), which is responsible for Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy, has escaped all attempts at elucidation due to its insolubility and propensity to aggregate. PrP
Externí odkaz:
https://doaj.org/article/4b7287383b1e4cef8460e63c196b4ad4
Autor:
Rosa L. Cordeiro, Camila R. Santos, Mariane N. Domingues, Tatiani B. Lima, Renan A. S. Pirolla, Mariana A. B. Morais, Felippe M. Colombari, Renan Y. Miyamoto, Gabriela F. Persinoti, Antonio C. Borges, Marcelo A. de Farias, Fabiane Stoffel, Chao Li, Fabio C. Gozzo, Marin van Heel, Marcelo E. Guerin, Eric J. Sundberg, Lai-Xi Wang, Rodrigo V. Portugal, Priscila O. Giuseppe, Mario T. Murakami
Publikováno v:
Nature Chemical Biology. 19:218-229
Bifidobacteria are early colonizers of the human gut and play central roles in human health and metabolism. To thrive in this competitive niche, these bacteria evolved the capacity to use complex carbohydrates, including mammalian N-glycans. Herein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82367075aa941797d3b70c7c3248d91e
https://doi.org/10.1038/s41589-022-01202-4
https://doi.org/10.1038/s41589-022-01202-4
Autor:
Marin van Heel
Publikováno v:
Proceedings of the European Microscopy Congress 2020.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::201484391551bd3766f76c631935d0bd
https://doi.org/10.22443/rms.emc2020.330
https://doi.org/10.22443/rms.emc2020.330
Autor:
Andressa A Pinto, Ana Paula Ulian de Araújo, Richard Charles Garratt, Samuel Leite Guimarães, Humberto D'Muniz Pereira, Rodrigo Villares Portugal, D. C. Mendonça, Andre S. Godoy, Marin van Heel, Marcelo Alexandre de Farias
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
In order to form functional filaments, human septins must assemble into hetero-oligomeric rod-like particles which polymerize end-to-end. The rules governing the assembly of these particles and the subsequent filaments are incompletely understood. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901c85167124053e3fa70d7470c23bc3
Autor:
Marcelo Alexandre de Farias, Rodrigo Villares Portugal, Edson R. Leite, Gabriel R. Schleder, João B. Souza Junior, Felippe M. Colombari, Jefferson Bettini, Marin van Heel, Adalberto Fazzio
Publikováno v:
The journal of physical chemistry letters. 11(4)
In recent years, cryogenic electron microscopy (Cryo-EM) has revolutionized the structure determination of wet samples and especially that of biological macromolecules. The glassy-water medium in which the molecules are embedded is considered an almo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cfb46de6c2bd78ed90e52b2d4e986b
https://pubmed.ncbi.nlm.nih.gov/32023063
https://pubmed.ncbi.nlm.nih.gov/32023063
Publikováno v:
Open Journal of Statistics. :701-739
Biology is a challenging and complicated mess. Understanding this challenging complexity is the realm of the biological sciences: Trying to make sense of the massive, messy data in terms of discovering patterns and revealing its underlying general ru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc37c0499c37e5afed7737a3a45ab4f8
https://doi.org/10.4236/ojs.2016.64059
https://doi.org/10.4236/ojs.2016.64059
Autor:
Mariana Fioramonte, Cristiano L. P. Oliveira, Rodrigo Villares Portugal, Fabio Cezar Gozzo, Marin van Heel
Publikováno v:
Introduction to Biomolecular Structure and Biophysics ISBN: 9789811049675
Solution studies permit a direct investigation of the particles on a well-defined environment. A number of thermodynamic and spectroscopic methods can be used directly in solution providing important structural information. In this work, hydrogen deu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd5875dbf5ba7ce11ce6a2e3d8e1bab0
https://doi.org/10.1007/978-981-10-4968-2_9
https://doi.org/10.1007/978-981-10-4968-2_9
Publikováno v:
Acta Crystallographica Section D Structural Biology, 69, 852-859
Flash-cooled three-dimensional crystals of the small protein lysozyme with a thickness of the order of 100 nm were imaged by 300 kV cryo-EM on a Falcon direct electron detector. The images were taken close to focus and to the eye appeared devoid of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41adc20f3d55f21f42468af4d816ea3c
https://doi.org/10.1107/s0907444913002734
https://doi.org/10.1107/s0907444913002734