Efficacy and Safety of Durvalumab Combined with Daratumumab in Daratumumab-Refractory Multiple Myeloma Patients

Autor: Frerichs, Kristine A Verkleij, Christie PM Dimopoulos, Meletios A Marin Soto, Jhon A Zweegman, Sonja Young, Mary H Newhall, Kathryn J Mutis, Tuna van de Donk, Niels WCJ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::12b520d5c4c1a31f8a65b8e4d41b8cb8
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2955223

Preclinical Activity of JNJ-7957, a Novel BCMA ×CD3 Bispecific Antibody for the Treatment of Multiple Myeloma, Is Potentiated by Daratumumab

Autor: Frerichs, Kristine A., Broekmans, Marloes E. C., Marin Soto, Jhon A., van Kessel, Berris, Heymans, Martijn W., Holthof, Lisa C., Verkleij, Christie P. M., Boominathan, Rengasamy, Vaidya, Bhavesh, Sendecki, Jocelyn, Axel, Amy, Gaudet, Francois, Pillarisetti, Kodandaram, Zweegman, Sonja, Adams, Homer C., Mutis, Tuna, van de Donk, Niels W. C. J.

Publikováno v: Frerichs, K A, Broekmans, M E C, Marin Soto, J A, van Kessel, B, Heymans, M W, Holthof, L C, Verkleij, C P M, Boominathan, R, Vaidya, B, Sendecki, J, Axel, A, Gaudet, F, Pillarisetti, K, Zweegman, S, Adams, H C, Mutis, T, van de Donk, N W C J & van de Donk, N W C J 2020, ' Preclinical Activity of JNJ-7957, a Novel BCMA ×CD3 Bispecific Antibody for the Treatment of Multiple Myeloma, Is Potentiated by Daratumumab ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 26, no. 9, pp. 2203-2215 . https://doi.org/10.1158/1078-0432.CCR-19-2299
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(9), 2203-2215. American Association for Cancer Research Inc.

Purpose: Multiple myeloma (MM) patients with disease refractory to all available drugs have a poor outcome, indicating the need for new agents with novel mechanisms of action. Experimental Design: We evaluated the anti-MM activity of the fully human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd3605d40cad97423f9f92a8c5a45ad
https://research.vumc.nl/en/publications/d2edb5dc-7418-4f69-bbde-eb3b619ae851

CD38-targeting antibodies in multiple myeloma: mechanisms of action and clinical experience.

Autor: Frerichs, Kristine A., Nagy, Noemi Anna, Lindenbergh, Pieter L., Bosman, Patty, Marin Soto, Jhon, Broekmans, Marloes, Groen, Richard W. J., Themeli, Maria, Nieuwenhuis, Louise, Stege, Claudia, Nijhof, Inger S., Mutis, Tuna, Zweegman, Sonja, Lokhorst, Henk M., van de Donk, Niels W. C. J.

Publikováno v: Expert Review of Clinical Immunology; Mar2018, Vol. 14 Issue 3, p197-206, 10p