Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marin Ming"'
Autor:
Bing Li, Irina V. Ustyugova, Lisa Szymkowicz, Shaolong Zhu, Marin Ming, Karen Y. Y. Fung, Guadalupe Cortés, D. Andrew James, Michael Hrynyk, Nausheen Rahman, Roger H. Brookes, Salvador F. Ausar
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTCurrent influenza vaccines could be augmented by including recombinant neuraminidase (rNA) protein antigen to broaden protective immunity and improve efficacy. Toward this goal, we investigated formulation conditions to optimize rNA physicoch
Externí odkaz:
https://doaj.org/article/b9a83ae88c824934944cdcb2de84a9be
Autor:
Jason Szeto, Aruun Beharry, Tricia Chen, Eric Zholumbetov, Emilie Daigneault, Marin Ming, Iain Lounsbury, Nelson Eng, Nemika Thangavadivel, Robbie Jin, Aurélie Denis-Jacquot, Bahram Behnam Azad, Meili Li, Diana Keizner, Marcus Liu, Sophia S. F. Lee, Kai He, Beata Gajewska
Publikováno v:
Vaccines, Vol 11, Iss 2, p 275 (2023)
There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present ethical concerns. The development of relevant in vitro assays is part of the solution. Using
Externí odkaz:
https://doaj.org/article/947b209ed417416e82d89ff044c1a03a
Autor:
Camille Houy, Marin Ming, Luciano Ettorre, Robbie Jin, Nemika Thangavadivel, Tricia Chen, Jin Su, Beata Gajewska
Publikováno v:
Vaccines, Vol 10, Iss 5, p 775 (2022)
In the vaccine industry, multiple physicochemical, immunological, in vitro and in vivo analytical methods are applied throughout the manufacturing process to characterize and monitor the quality of vaccines. Presented here is the Single Epitope Antig
Externí odkaz:
https://doaj.org/article/8fb2450be57c4a3ea250d6e45148c860
Autor:
Marin Ming, Judy Caterini, Luciano Ettorre, Mei Tang, Martha Schreiber, Danielle Salha, Lucy Gisonni-Lex
Publikováno v:
Biologicals. 80:53
Autor:
Danielle Salha, Marin Ming, Nidhi Kapoor, Kimberley Williams, Pappachan E. Kolattukudy, Beata Gajewska, Lidice Bernardo, Fabienne Piras, Leslie G. Chan, Anke Pagnon, Jin Su, Lucy Gisonni-Lex
Publikováno v:
Vaccine. 37:2960-2966
Potency assays for vaccine products are an important regulatory requirement, and are used to assess product quality and consistency prior to lot release for clinical testing. Ideally they measure an established correlate of efficacy or protection. In
Autor:
Danielle Salha, Martha Schreiber, Judy Caterini, Mei Tang, Luciano Ettorre, Lucy Gisonni-Lex, Marin Ming
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 68
Replacement of the potency tests for diphtheria vaccines is a high priority for the international initiative to reduce, refine, and replace animal use in vaccine testing. Diphtheria toxoid containing vaccine products marketed in the US currently requ
Autor:
Scott Gallichan, Robert Hopfer, Roger H. Brookes, Martina Ochs, Kimberley Williams, Sanjay Gurunathan, Mei Tang, Marin Ming
Publikováno v:
Human Vaccines & Immunotherapeutics
Currently marketed Streptococcus pneumoniae vaccines are based on polysaccharide capsular antigens from the most common strains. Pneumococcal histidine triad protein D (PhtD) is a conserved surface protein that is being evaluated as a candidate for a
Publikováno v:
Journal of immunological methods. 452
We have developed an accurate, precise and stability-indicating flow cytometry (FC) based assay to directly measure antigenicity of H4 protein (also known as HyVac4) in a vaccine formulation of H4-IC31, without desorbing the H4 protein from the IC31
Autor:
Robert Hopfer, Jason Szeto, Karen Ogilvie, Carol L. Claus, Germie P. J. M. van den Dobbelsteen, Marin Ming, Scott Gallichan, Danielle Salha, Mei Tang, Belma Ljutic, David Hanwell, Lisa E. Myers, Benjamin Messham, Martina Ochs, Anthony Sheung
Publikováno v:
Infection and Immunity. 80:2212-2220
Streptococcus pneumoniae pneumolysin (PLY) is a virulence factor that causes toxic effects contributing to pneumococcal pneumonia. To date, deriving a PLY candidate vaccine with the appropriate detoxification and immune profile has been challenging.
Autor:
Benjamin Messham, Martina Ochs, Belma Ljutic, Marin Ming, Kevin Harper, Annie Dookie, Salvador F. Ausar
Publikováno v:
Vaccine. 30(19)
We investigated the immunogenicity, stability and adsorption properties of an experimental pneumococcal vaccine composed of three protein vaccine antigens; Pneumococcal histidine triad protein D, (PhtD), Pneumococcal choline-binding protein A (PcpA)