Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Marin Veldic"'
Autor:
Alessandro Miola, Michele De Prisco, Marialaura Lussignoli, Nicola Meda, Elisa Dughiero, Riccardo Costa, Nicolas A. Nunez, Michele Fornaro, Marin Veldic, Mark A. Frye, Eduard Vieta, Marco Solmi, Joaquim Radua, Fabio Sambataro
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
ObjectiveBipolar Disorder (BD) is a severe mental illness associated with high rates of general medical comorbidity, reduced life expectancy, and premature mortality. Although BD has been associated with high medical hospitalization, the factors that
Externí odkaz:
https://doaj.org/article/9f028bd16d6b4b09aa0d26303d890946
Autor:
Nicolas A. Nuñez, Brandon J. Coombes, Lindsay Melhuish Beaupre, Aysegul Ozerdem, Manuel Gardea Resendez, Francisco Romo-Nava, David J. Bond, Marin Veldic, Balwinder Singh, Katherine M. Moore, Hannah K. Betcher, Simon Kung, Miguel L. Prieto, Manuel Fuentes, Mete Ercis, Alessandro Miola, Jorge A. Sanchez Ruiz, Gregory Jenkins, Anthony Batzler, Jonathan G. Leung, Alfredo Cuellar-Barboza, Susannah J. Tye, Susan L. McElroy, Joanna M. Biernacka, Mark A. Frye
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-5 (2024)
Abstract There is increasing interest in individualizing treatment selection for more than 25 regulatory approved treatments for major depressive disorder (MDD). Despite an inconclusive efficacy evidence base, antidepressants (ADs) are prescribed for
Externí odkaz:
https://doaj.org/article/30895815cfaa4cdd8a949170cc6615ae
Autor:
Nicolas A. Nuñez, Sofia Jezzini-Martinez, Ada Man-Choi Ho, Manuel Gardea-Resendez, Larry J. Prokop, Balwinder Singh, Paola Margarita Robledo-Atilano, Francisco Romo-Nava, Marin Veldic, Susan L. McElroy, Mark A. Frye, Alfredo B Cuellar-Barboza
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 10, Iss , Pp 100092- (2024)
Introduction: Psychostimulants are FDA-approved for treating attention deficit hyperactivity disorder (ADHD). They are often prescribed off-label for mood disorders (in the majority of cases for augmentation of major depressive disorder [MDD] or trea
Externí odkaz:
https://doaj.org/article/27003a88bd30469b85fa97d090be58d1
Autor:
Nicolas A. Nunez, Brandon J. Coombes, Francisco Romo-Nava, David J. Bond, Jennifer Vande Voort, Paul E. Croarkin, Nicole Leibman, Manuel Gardea Resendez, Marin Veldic, Hannah Betcher, Balwinder Singh, Colin Colby, Alfredo Cuellar-Barboza, Miguel Prieto, Katherine M. Moore, Aysegul Ozerdem, Susan L. McElroy, Mark A. Frye, Joanna M. Biernacka
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Background:Bipolar disorder (BD) with co-occurring attention deficit-hyperactivity disorder (ADHD) is associated with an unfavorable course of illness. We aimed to identify potential clinical and genetic correlates of BD with and without ADHD.Methods
Externí odkaz:
https://doaj.org/article/1eeb2279ff6440a9bb8be087b4191bc6
Autor:
Alfredo B. Cuéllar-Barboza, Susan L. McElroy, Marin Veldic, Balwinder Singh, Simon Kung, Francisco Romo-Nava, Nicolas A. Nunez, Alejandra Cabello-Arreola, Brandon J. Coombes, Miguel Prieto, Hannah K. Betcher, Katherine M. Moore, Stacey J. Winham, Joanna M. Biernacka, Mark A. Frye
Publikováno v:
International Journal of Bipolar Disorders, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Background Treatment in bipolar disorder (BD) is commonly applied as a multimodal therapy based on decision algorithms that lack an integrative understanding of molecular mechanisms or a biomarker associated clinical outcome measure. Pharmac
Externí odkaz:
https://doaj.org/article/8aad87cd6dc64ddbb96b43f45b49089a
Autor:
Henry Sershen, Alessandro Guidotti, James Auta, Jenny Drnevich, Dennis R. Grayson, Marin Veldic, Jordan Meyers, Mary Youseff, Adrian Zhubi, Keturah Faurot, Renrong Wu, Jingping Zhao, Hua Jin, Abel Lajtha, John M. Davis, Robert C. Smith
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 5, Iss , Pp 100038- (2021)
Some of the biochemical abnormalities underlying schizophrenia, involve differences in methylation and methylating enzymes, as well as other related target genes. We present results of a study of differences in mRNA expression in peripheral blood lym
Externí odkaz:
https://doaj.org/article/0bbbabdd6f1d471e9a975af204f3de47
Autor:
Ada Man-Choi Ho, Stacey J. Winham, Bryan M. McCauley, Marija Kundakovic, Keith D. Robertson, Zhifu Sun, Tamas Ordog, Lauren M. Webb, Mark A. Frye, Marin Veldic
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Rapid cycling (RC) burdens bipolar disorder (BD) patients further by causing more severe disability and increased suicidality. Because diagnosing RC can be challenging, RC patients are at risk of rapid decline due to delayed suitable treatment. Here,
Externí odkaz:
https://doaj.org/article/043abd74a9934f2b9b733de5c9728bc4
Autor:
Manuel Gardea-Resendez, Mehmet Utku Kucuker, Caren J. Blacker, Ada M.-C. Ho, Paul E. Croarkin, Mark A. Frye, Marin Veldic
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundEpimutations secondary to gene-environment interactions have a key role in the pathophysiology of major psychiatric disorders. In vivo and in vitro evidence suggest that mood stabilizers can potentially reverse epigenetic deregulations foun
Externí odkaz:
https://doaj.org/article/7763ff99fad54427aeff64bf8c3ef778
Autor:
Marin Veldic, Ahmed T. Ahmed, Caren J. Blacker, Jennifer R. Geske, Joanna M. Biernacka, Kristin L. Borreggine, Katherine M. Moore, Miguel L. Prieto, Jennifer L. Vande Voort, Paul E. Croarkin, Astrid A. Hoberg, Simon Kung, Renato D. Alarcon, Nicola Keeth, Balwinder Singh, William V. Bobo, Mark A. Frye
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Pharmacogenomic testing, specifically for pharmacokinetic (PK) and pharmacodynamic (PD) genetic variation, may contribute to a better understanding of baseline genetic differences in patients seeking treatment for depression, which may fu
Externí odkaz:
https://doaj.org/article/39bb551daf2f485885d47192dd557e52
Autor:
Yun-Fang Jia, YuBin Choi, Jennifer R. Ayers-Ringler, Joanna M. Biernacka, Jennifer R. Geske, Daniel R. Lindberg, Susan L. McElroy, Mark A. Frye, Doo-Sup Choi, Marin Veldic
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
While downregulation of excitatory amino acid transporter 2 (EAAT2), the main transporter removing glutamate from the synapse, has been recognized in bipolar disorder (BD), the underlying mechanisms of downregulation have not been elucidated. BD is i
Externí odkaz:
https://doaj.org/article/d7b36e43d4dd453b8cc1d7dc218479b1