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pro vyhledávání: '"Marilyn V Zeman"'
Autor:
Marilyn V Zeman, Gideon M Hirschfield
Publikováno v:
Canadian Journal of Gastroenterology, Vol 24, Iss 4, Pp 225-231 (2010)
Confirming whether a patient has autoimmune liver disease is challenging, given its varied presentation and complex definitions. In the continued absence of pathognomonic serum markers, diagnosis requires evaluation of laboratory investigations and,
Externí odkaz:
https://doaj.org/article/8fd7faee03cc430ba57f4e4bc155afac
Autor:
Rachel F. Tyndale, Mohammad I. Zia, Laurent Bodin, Yushu Rao, Marilyn V. Zeman, Edward M. Sellers, Ewa Hoffmann
Publikováno v:
Molecular Pharmacology. 58:747-755
In humans, 80% of nicotine is metabolized to the inactive metabolite cotinine by the enzyme CYP2A6, which can also activate tobacco smoke procarcinogens (e.g., 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone). Previously, we demonstrated that individu
Autor:
Marilyn V. Zeman, Rachel F. Tyndale, Mirjana V. Djordjevic, Edward M. Sellers, Yamini Ramamoorthy
Publikováno v:
Nicotinetobacco research : official journal of the Society for Research on Nicotine and Tobacco. 5(6)
Nicotine is metabolized to the inactive metabolite cotinine by cytochrome P450 2A6. NNK, or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is a potent procarcinogen shown to be activated to a reactive mutagenic metabolite by the enzyme CYP2A6. We st
Publikováno v:
Journal of women's healthgender-based medicine. 11(2)
Men and women are thought to regulate their smoking differently and to differ in their susceptibility to nicotine addiction.Various measures of smoke exposure were compared between 400 current regular tobacco-dependent (DSM-IV) male and female light