Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Marilyn T. Marron"'
Autor:
Amanda F. Baker, Marilyn T. Marron, Linda L. Garland, Neale T. Hanke, Elliot Imler, Bruce Seligmann
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 144:1317-1327
We previously showed that carfilzomib (CFZ) has potent anti-proliferative and cytotoxic activity in a broad range of lung cancer cell lines. Here we investigate possible mechanisms of CFZ acquired resistance in lung cancer cell lines. CFZ-resistant n
Autor:
Jie Ding, Marilyn T. Marron, Maria I. Altbach, Chuan Huang, Yi Gao, Denise J. Roe, Betsy C. Wertheim, Alison Stopeck, Cynthia A. Thomson, Jean Philippe Galons, Patricia A. Thompson, Gertraud Maskarinec, Fang Wang
Publikováno v:
Journal of Magnetic Resonance Imaging. 48:971-981
BACKGROUND Increased breast density is a significant independent risk factor for breast cancer, and recent studies show that this risk is modifiable. Hence, breast density measures sensitive to small changes are desired. PURPOSE Utilizing fat-water d
Autor:
Maria I. Altbach, Denise J. Roe, Patricia A. Thompson, J-P Galons, F Wang, Betsy C. Wertheim, Jie Ding, Marilyn T. Marron, Alison Stopeck, Cynthia A. Thomson, Chuan Huang
Publikováno v:
Cancer Research. 77:P6-09
Objective: Tamoxifen (TAM) lowers breast cancer recurrence by 40-50% with evidence of individual variability in responsiveness. A ≥10% decrease in mammography-determined breast density (BD) after 12–18 months of TAM use has been associated with c
Autor:
Alison Stopeck, Denise J. Roe, Maria Iannone, Robert B. Livingston, Marilyn T. Marron, Pavani Chalasani, Kathryn Clarke, Joseph Shan
Publikováno v:
Cancer Medicine
Bavituximab is a chimeric monoclonal antibody that targets phosphatidylserine (PS). PS is externalized on cells in the tumor microenvironment when exposed to hypoxia and/or other physiological stressors. On attaching to PS, bavituximab is thought to
Autor:
Jie, Ding, Alison T, Stopeck, Yi, Gao, Marilyn T, Marron, Betsy C, Wertheim, Maria I, Altbach, Jean-Philippe, Galons, Denise J, Roe, Fang, Wang, Gertraud, Maskarinec, Cynthia A, Thomson, Patricia A, Thompson, Chuan, Huang
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 48(4)
BACKGROUND: Increased breast density is a significant independent risk factor for breast cancer, and recent studies show that this risk is modifiable. Hence, breast density measures sensitive to small changes are desired. PURPOSE: Utilizing fat-water
Autor:
Susan Lindquist, E. M. Kithsiri Wijeratne, Ruth Scherz-Shouval, Manping X. Liu, Letícia V. Costa-Lotufo, Sandro Santagata, Luke Whitesell, Ya Ming Xu, Marilyn T. Marron, Danilo D. Rocha, A. A. Leslie Gunatilaka
Publikováno v:
Journal of Medicinal Chemistry. 57:2851-2863
To understand the relationship between the structure and the remarkably diverse bioactivities reported for withanolides, we obtained withaferin A (WA; 1) and 36 analogues (2−37) and compared their cytotoxicity to cytoprotective heat-shock-inducing
Autor:
Maria Iannone, Pavani Chalasani, Alison Stopeck, Jennifer M. Specht, Robert B. Livingston, Ursa Brown-Glaberman, Marilyn T. Marron
Publikováno v:
Disease Markers
Disease Markers, Vol 2016 (2016)
Disease Markers, Vol 2016 (2016)
Introduction. Carbonic anhydrase IX (CAIX) is a hypoxia regulated metalloenzyme integral to maintaining cellular pH. Increased CAIX expression is associated with poor prognosis in breast cancer. To explore CAIX as a biomarker for breast cancer therap
Autor:
Ryan C. Scolnik, Long N. Trinh, Sage P. Vissering, A. A. Leslie Gunatilaka, Maria T. Williams, Vu K. Truong, Emily L. Goldberg, Cristina G. Contreras, Raina M. Maier, Rebecca L. Low, Alison L. Ange, Robert B. Bates, Adria A. Bodour, Kathryn M. Marlor, Malgorzata Strelczuk, Marilyn T. Marron, Bonnie L. Bell, Samiul M. Ahad, Bryan R. Bourne, Matthew J. Streeter, Albert K. Lee, Sheryl King, Megan C. Weick
Publikováno v:
Tetrahedron. 66:9107-9112
Syntheses of the bacterial surfactants 6S,6S-, 9S,9S-, and 9U,9U-flavolipids confirmed the structures proposed for them from spectroscopic analysis of a flavolipid mixture and made pure flavolipids available for the first time. All three synthetic fl
Autor:
Jennifer M. Specht, Marilyn T. Marron, Robert B. Livingston, Maria Iannone, Pavani Chalasani, Ursa Brown-Glaberman, Alison Stopeck
Publikováno v:
Cancer Research. 73:P1-03
Introduction: Carbonic anhydrase-IX (CAIX) facilitates the reversible hydration of carbon dioxide to bicarbonate and protons, a process integral to maintaining pH differences across the cancer cell plasma membrane. CAIX is regulated by hypoxia induci
Autor:
Dennis T. Ray, Luke Whitesell, A. A. Leslie Gunatilaka, Marilyn T. Marron, Steven P. McLaughlin, Emily Seddon, Ya Ming Xu
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:2210-2214
Preparations of the roots of the medicinal plant Withania somnifera (L.) Dunal commonly called ashwagandha have been used for millennia in the Ayurvedic medical tradition of India as a general tonic to relieve stress and enhance health, especially in