Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Marilyn Mathew"'
1
Akademický článek
Induction of Oxidative Stress and Ferroptosis in Triple-Negative Breast Cancer Cells by Niclosamide via Blockade of the Function and Expression of SLC38A5 and SLC7A11
Autor: Marilyn Mathew, Sathish Sivaprakasam, Gunadharini Dharmalingam-Nandagopal, Souad R. Sennoune, Nhi T. Nguyen, Valeria Jaramillo-Martinez, Yangzom D. Bhutia, Vadivel Ganapathy
Publikováno v: Antioxidants, Vol 13, Iss 3, p 291 (2024)
The amino acid transporters SLC38A5 and SLC7A11 are upregulated in triple-negative breast cancer (TNBC). SLC38A5 transports glutamine, methionine, glycine and serine, and therefore activates mTOR signaling and induces epigenetic modifications. SLC7A1
Externí odkaz: https://doaj.org/article/3daedfbc71a246f0a273bad44bddad1d
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2
Akademický článek
Unconventional Functions of Amino Acid Transporters: Role in Macropinocytosis (SLC38A5/SLC38A3) and Diet-Induced Obesity/Metabolic Syndrome (SLC6A19/SLC6A14/SLC6A6)
Autor: Yangzom D. Bhutia, Marilyn Mathew, Sathish Sivaprakasam, Sabarish Ramachandran, Vadivel Ganapathy
Publikováno v: Biomolecules, Vol 12, Iss 2, p 235 (2022)
Amino acid transporters are expressed in mammalian cells not only in the plasma membrane but also in intracellular membranes. The conventional function of these transporters is to transfer their amino acid substrates across the lipid bilayer; the dir
Externí odkaz: https://doaj.org/article/1fa84197984d4a1e9bd2729c89550a0f
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3
Potent Inhibition of Macropinocytosis by Niclosamide in Cancer Cells: A Novel Mechanism for the Anticancer Efficacy for the Antihelminthic
Autor: Souad R. Sennoune, Gunadharini Dharmalingam Nandagopal, Sabarish Ramachandran, Marilyn Mathew, Sathish Sivaprakasam, Valeria Jaramillo-Martinez, Yangzom D. Bhutia, Vadivel Ganapathy
Publikováno v: Cancers
Volume 15
Issue 3
Pages: 759
Niclosamide, a drug used to treat tapeworm infection, possesses anticancer effects by interfering with multiple signaling pathways. Niclosamide also causes intracellular acidification. We have recently discovered that the amino acid transporter SLC38
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b5fd1e6d7dda56d300857478299ab4
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4
Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues
Autor: Marilyn Mathew, Sathish Sivaprakasam, Jennifer L. Phy, Yangzom D. Bhutia, Vadivel Ganapathy
Publikováno v: Bioscience Reports. 43
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder in women with components of significant genetic predisposition and possibly multiple, but not yet clearly defined, triggers. This disorder shares several clinical features with h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab4020de31c878f9e189a7d6fdaf9e7
https://doi.org/10.1042/bsr20212234
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5
Together – apart: in touch in a time of separation
Autor: Marilyn Mathew
Publikováno v: Journal of Analytical Psychology. 66:463-483
This paper explores the experience of working as a Jungian analyst through the various phases of the global COVID-19 pandemic, examining the importance of the physical containing space alongside the analyst's internal mind and how technology can both
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28af65134e7f6077d48e77c0bcb6a96
https://doi.org/10.1111/1468-5922.12679
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8
Aqua vitae, aqua permanens: dreaming, drowning, swimming and surfing in analysis
Autor: Marilyn Mathew
Publikováno v: Journal of Analytical Psychology. 63:295-304
In response to the question 'Who is My Jung?', this paper describes the profound personal impact of Jung's creative / artistic approach to the unconscious, beginning with my discovery of The Red Book at the age of twelve. Echoing the flow of my own d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d49b98fdeaedebb3eaa4a62b3883d1e
https://doi.org/10.1111/1468-5922.12410
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10
Reverie: between thought and prayer
Autor: Marilyn Mathew
Publikováno v: Journal of Analytical Psychology. 50:383-393
Taking inspiration from a quotation by Lao Tzu, this paper considers ‘reverie’ as a dynamic process of containment as well as a state of mind. Reverie as a quality of thought akin to prayer is explored in the relationship between self and other.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f499981a57cc1b98aa179f0c4aa73abe
https://doi.org/10.1111/j.0021-8774.2005.00539.x
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