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pro vyhledávání: '"Marilyn Lemmon"'
Autor:
Larry Boyle, Leisa Johnson, Frank McCormick, Annie Shen, John Kunich, Ali Fattaey, Terry Hermiston, Marilyn Lemmon, Marty Giedlin, Kusum Pandey
Publikováno v:
Cancer Cell. 1:325-337
We have engineered a human adenovirus, ONYX-411, that selectively replicates in human tumor cells, but not normal cells, depending upon the status of their retinoblastoma tumor suppressor protein (pRB) pathway. Early and late viral gene expression as
Autor:
Hilde, Stubdal, Noah, Perin, Marilyn, Lemmon, Patricia, Holman, Maxine, Bauzon, Philip M, Potter, Mary K, Danks, Ali, Fattaey, Thomas, Dubensky, Leisa, Johnson
Publikováno v:
Cancer research. 63(20)
ONYX-015 has been used successfully in the clinic as a cancer therapeutic in combination with chemotherapy. The combination of ONYX-015 and chemotherapy appears to be more efficacious than either regimen alone. In this study, we try to enhance this c