Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marilyn L. Keeler"'
Autor:
Suresh K. Jain, Marilyn L. Keeler, Nadia Carlesso, Lyuba Varticovski, Brian Druker, Mira Susa
Publikováno v:
Scopus-Elsevier
BCR/abl is a chimeric oncogene implicated in the pathogenesis of human chronic myelogenous leukemia. Expression of the BCR/abl gene induces hematologic malignancies in transgenic mice and transformation of interleukin-3-dependent hematopoietic cells.
Publikováno v:
Cellular Immunology. 156:378-388
The intracellular portion of the IL-2 receptor (IL-2R) signal transducing beta-chain contains a distinct region, designated "serine-rich," which encompasses sequences required for IL-2-mediated cell growth. Although the receptor does not possess intr
Publikováno v:
Oncogene. 24(53)
The Mdm2 and Mdm4 genes are amplified and overexpressed in a variety of human cancers and encode structurally related oncoproteins that bind to the p53 tumor suppressor protein and inhibit p53 activity. Mice deleted for either Mdm2 or Mdm4 die during
Autor:
James W. Horner, Robert W. Finberg, Roderick T. Bronson, Anna M. Cerny, Ronald A. DePinho, Damon R. Asher, Marilyn L. Keeler, Stephen N. Jones, Mychell A. Neptune, Sarah R. Weiler
Publikováno v:
Genesis (New York, N.Y. : 2000). 42(2)
The coxsackievirus and adenovirus receptor (CAR) is a transmembrane protein that is known to be a site of viral attachment and entry, but its physiologic functions are undefined. CAR expression is maximal in neonates and wanes rapidly after birth in
Publikováno v:
Biochimica et biophysica acta. 1226(1)
Autor:
Damon R. Asher, Anna M. Cerny, Sarah R. Weiler, James W. Horner, Marilyn L. Keeler, Mychell A. Neptune, Stephen N. Jones, Roderick T. Bronson, Ronald A. DePinho, Robert W. Finberg
Publikováno v:
Genesis: The Journal of Genetics & Development; Jun2005, Vol. 42 Issue 2, p77-85, 9p
Autor:
Phillip J. Robinson, Suniti Misra, Marilyn L. Keeler, Kate A. Powell, Duygu Harrison-Findik, Suresh K. Jain, Chandra S. Malladi, Lyuba Varticovski
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (1):10-19
Phosphatidylinositol 3-kinase (PI 3-kinase) plays a role in late stages of endocytosis as well as in cellular proliferation and transformation. The SH3 domain of its regulatory p85 subunit stimulates the GTPase activity of dynamin in vitro. Dynamin i
Publikováno v:
Scopus-Elsevier
Phosphatidylinositol 3-kinase (PI 3-kinase) activity has been detected in immune complexes with active protein tyrosine kinases, and its products have been measured in intact cells in response to growth stimuli. Both methods do not directly evaluate
Externí odkaz:
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http://www.scopus.com/inward/record.url?eid=2-s2.0-0026482524&partnerID=MN8TOARS